Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   EL147_RS06350 Genome accession   NZ_LR134341
Coordinates   1297421..1298680 (+) Length   419 a.a.
NCBI ID   WP_007893844.1    Uniprot ID   G5K7I4
Organism   Streptococcus pseudoporcinus strain NCTC13786     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1292421..1303680
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL147_RS06330 (NCTC13786_01266) mutL 1292948..1294915 (+) 1968 WP_007893835.1 DNA mismatch repair endonuclease MutL -
  EL147_RS06335 (NCTC13786_01267) - 1294926..1296149 (+) 1224 WP_007893804.1 MFS transporter -
  EL147_RS06340 (NCTC13786_01268) ruvA 1296151..1296744 (+) 594 WP_007893783.1 Holliday junction branch migration protein RuvA -
  EL147_RS06345 (NCTC13786_01269) - 1296751..1297305 (+) 555 WP_007893754.1 DNA-3-methyladenine glycosylase I -
  EL147_RS06350 (NCTC13786_01270) cinA 1297421..1298680 (+) 1260 WP_007893844.1 competence/damage-inducible protein A Machinery gene
  EL147_RS06355 (NCTC13786_01271) recA 1298770..1299912 (+) 1143 WP_007893872.1 recombinase RecA Machinery gene
  EL147_RS06360 (NCTC13786_01272) spx 1300318..1300716 (+) 399 WP_007893913.1 transcriptional regulator Spx -
  EL147_RS06365 (NCTC13786_01273) - 1300828..1301097 (+) 270 WP_003083367.1 IreB family regulatory phosphoprotein -
  EL147_RS06370 (NCTC13786_01274) ruvX 1301094..1301513 (+) 420 WP_007893744.1 Holliday junction resolvase RuvX -
  EL147_RS06375 (NCTC13786_01275) - 1301524..1301823 (+) 300 WP_007893854.1 DUF1292 domain-containing protein -
  EL147_RS06380 (NCTC13786_01276) - 1301951..1303513 (+) 1563 WP_007893784.1 hypothetical protein -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45675.37 Da        Isoelectric Point: 5.5749

>NTDB_id=1122013 EL147_RS06350 WP_007893844.1 1297421..1298680(+) (cinA) [Streptococcus pseudoporcinus strain NCTC13786]
MKAEIVTVGTEILTGQILNTNAQFLSEKMAEIGVDIYFQTAVGDNKDRLLEVLAIASKRSDLVILCGGLGPTEDDLTKQT
LASFLGRDLIFDKEARDKLDRFFASRPQGSRTTNNERQAQLIEGSRPIQNITGLAVGGLVESGGVSYVVLPGPPSELIPM
VNQQLLPMLTATQTRLYSRVLRFFGIGESQLVTVLANFISEQTDPTIAPYAKIGEVTLRLSTKALGLIEANQKLDKLEKA
ILDTPTMDSIPLRQFFYGYGEDNSLSREVVQLLKQKKKKLTAAESLTAGLFQSTLANYAGISEFFSGGFVTYSMLEKSRM
LNIPLSDLQANGVVSHYTAREMAEKARLLTESDIGISLTGVAGPDSLEGHEAGTVFIGISTEEKTDSIQIAIGGRTRSDI
RYIATLHAFNLVRKTLLKS

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=1122013 EL147_RS06350 WP_007893844.1 1297421..1298680(+) (cinA) [Streptococcus pseudoporcinus strain NCTC13786]
ATGAAAGCGGAGATTGTTACAGTAGGTACAGAGATCTTAACTGGTCAAATTCTCAATACGAATGCTCAGTTTTTATCCGA
AAAAATGGCTGAGATAGGAGTTGATATCTATTTTCAAACAGCCGTCGGGGACAACAAAGATCGTTTGCTGGAGGTTCTTG
CCATAGCAAGTAAACGTAGTGATCTTGTTATTCTGTGTGGAGGCCTTGGCCCAACAGAAGATGATTTAACCAAGCAAACA
TTAGCAAGTTTCTTGGGGCGTGATTTGATTTTCGACAAAGAGGCTAGGGATAAATTGGATCGCTTTTTTGCTTCTCGTCC
GCAAGGTTCGCGTACTACTAATAATGAGAGGCAGGCGCAGTTGATTGAAGGTTCAAGACCTATTCAAAATATTACGGGAC
TAGCGGTAGGAGGTTTGGTGGAGAGTGGCGGTGTTTCTTATGTTGTCTTACCTGGCCCTCCTTCTGAATTGATACCAATG
GTTAATCAACAGTTATTACCGATGCTGACTGCGACTCAGACTAGGCTTTATTCGCGTGTATTACGCTTTTTTGGTATTGG
TGAAAGTCAACTAGTCACTGTTCTAGCCAACTTCATATCTGAGCAGACTGATCCAACGATCGCGCCTTATGCCAAGATAG
GTGAAGTAACACTGCGTTTATCCACCAAGGCATTGGGGCTGATAGAGGCAAATCAAAAGCTAGATAAACTTGAAAAAGCT
ATTTTAGATACCCCAACGATGGACAGTATTCCCTTAAGGCAGTTCTTTTATGGTTATGGTGAAGATAATAGTTTATCAAG
GGAAGTTGTCCAGTTACTTAAGCAAAAGAAGAAAAAACTTACAGCAGCTGAGAGTCTAACAGCTGGACTTTTTCAGTCAA
CCTTAGCTAATTATGCAGGGATCTCTGAATTTTTTTCAGGCGGGTTTGTGACCTACAGTATGTTAGAAAAGTCAAGAATG
CTGAACATTCCTTTATCTGATTTACAAGCTAATGGGGTGGTTAGCCACTATACAGCCCGAGAAATGGCTGAGAAAGCGCG
GTTGTTAACTGAGTCAGATATAGGAATTAGTTTAACAGGTGTTGCAGGGCCAGATTCTCTAGAGGGACATGAGGCGGGAA
CTGTTTTTATCGGTATTTCGACAGAGGAAAAAACAGATTCTATCCAAATTGCAATTGGTGGACGGACTCGTTCTGATATT
CGTTATATAGCAACGCTACATGCTTTTAATTTGGTCCGAAAAACTTTATTAAAAAGTTGA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(263-416)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G5K7I4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

68.825

99.523

0.685
  cinA Streptococcus mitis SK321

68.345

99.523

0.68
  cinA Streptococcus pneumoniae TIGR4

68.345

99.523

0.68
  cinA Streptococcus pneumoniae Rx1

68.345

99.523

0.68
  cinA Streptococcus pneumoniae R6

68.345

99.523

0.68
  cinA Streptococcus pneumoniae D39

68.106

99.523

0.678
  cinA Streptococcus mitis NCTC 12261

67.626

99.523

0.673
  cinA Streptococcus suis isolate S10

52.644

99.284

0.523
  cinA Bacillus subtilis subsp. subtilis str. 168

45.933

99.761

0.458

Multiple sequence alignment