Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   EL140_RS08410 Genome accession   NZ_LR134336
Coordinates   1696031..1697287 (-) Length   418 a.a.
NCBI ID   WP_000642669.1    Uniprot ID   A0A0F2D2E5
Organism   Streptococcus oralis ATCC 35037 strain NCTC 11427     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1691031..1702287
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL140_RS08385 (NCTC11427_01654) - 1691486..1692202 (-) 717 WP_000532891.1 YebC/PmpR family DNA-binding transcriptional regulator -
  EL140_RS08390 (NCTC11427_01655) - 1692299..1693669 (-) 1371 WP_002874864.1 MATE family efflux transporter -
  EL140_RS08395 (NCTC11427_01656) - 1693779..1694333 (+) 555 WP_000060285.1 GNAT family N-acetyltransferase -
  EL140_RS08400 (NCTC11427_01657) - 1694464..1694658 (-) 195 WP_000415528.1 PspC domain-containing protein -
  EL140_RS08405 (NCTC11427_01658) recA 1694828..1695976 (-) 1149 WP_001085515.1 recombinase RecA Machinery gene
  EL140_RS08410 (NCTC11427_01659) cinA 1696031..1697287 (-) 1257 WP_000642669.1 competence/damage-inducible protein A Machinery gene
  EL140_RS08415 (NCTC11427_01660) brpA 1697360..1698400 (-) 1041 WP_000592174.1 biofilm formation/cell division transcriptional regulator BrpA -
  EL140_RS08420 (NCTC11427_01661) - 1698405..1698926 (-) 522 WP_000455521.1 GNAT family N-acetyltransferase -
  EL140_RS08425 (NCTC11427_01662) tsaE 1698916..1699359 (-) 444 WP_000556960.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  EL140_RS08430 (NCTC11427_01663) comM 1699443..1700066 (-) 624 WP_000240908.1 hypothetical protein Regulator
  EL140_RS08435 (NCTC11427_01664) ndk 1700201..1700620 (-) 420 WP_000438309.1 nucleoside-diphosphate kinase -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45247.63 Da        Isoelectric Point: 4.7813

>NTDB_id=1121866 EL140_RS08410 WP_000642669.1 1696031..1697287(-) (cinA) [Streptococcus oralis ATCC 35037 strain NCTC 11427]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEARLLSLLEIASQRSNLVILTGGLGPTEDDLTKQT
LAKFLGKDLVFDPQAQEKLDIFFAHRPDYARTPNNERQAQIVEGATPLPNETGLAVGGVLEVDGVTYVVLPGPPSELKPM
VLNQLLPMLMTGTKLYSRVLRFFGIGESQLVTILADLIDHQTDPTLAPYAKTGEVTLRLSTKAVSQEKADQALDILENQI
LDRQTFEGISLRDICYGYGEETSLASVVVEELKKRQKSITAAESLTAGLFQATLADFSGVSAIFNGGFVTYSLEEKSKML
DISEQELKEHGVVSEFTARKMAEQARLKTQSDYGVSLTGVAGPDSLEGHPAGTVFIGLAHAKGTEVIKANIAGRSRADVR
HIAVMHAFNLVRKTLLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=1121866 EL140_RS08410 WP_000642669.1 1696031..1697287(-) (cinA) [Streptococcus oralis ATCC 35037 strain NCTC 11427]
ATGAAAGCAGAAATTATTGCTGTCGGAACAGAAATTTTAACAGGGCAGATTGTCAATACCAATGCTCAGTTTTTATCAGA
GAAACTAGCCGAAATCGGGGTAGATGTCTACTTCCAAACTGCTGTTGGAGATAATGAAGCTCGTCTTTTGTCCTTGCTTG
AGATTGCGAGTCAACGTAGTAATCTTGTGATTTTGACAGGGGGCTTGGGACCAACTGAGGATGATTTGACCAAACAAACC
CTGGCAAAATTTTTAGGAAAAGATCTAGTGTTTGACCCTCAAGCGCAAGAGAAACTGGATATTTTCTTTGCTCATAGACC
TGACTATGCTCGGACACCGAATAATGAGCGCCAAGCCCAAATTGTAGAAGGGGCGACTCCACTGCCAAATGAGACAGGTT
TAGCAGTAGGAGGAGTATTGGAAGTGGATGGTGTAACCTACGTGGTCCTTCCAGGACCACCTAGTGAATTGAAACCTATG
GTATTAAATCAACTCTTGCCCATGCTGATGACAGGAACCAAACTGTACTCACGAGTGCTCCGTTTCTTTGGAATTGGGGA
GAGTCAGTTGGTGACCATTTTGGCGGATTTGATTGACCATCAAACCGATCCGACTTTGGCACCGTATGCCAAAACAGGAG
AAGTGACCTTGCGCTTGTCTACAAAAGCAGTTAGTCAAGAAAAGGCTGATCAAGCACTGGACATCTTAGAAAATCAAATC
TTGGATCGTCAAACTTTCGAGGGGATTTCTCTACGAGATATCTGTTATGGATATGGGGAAGAAACCAGCCTCGCAAGTGT
CGTTGTAGAAGAGCTAAAGAAGAGACAGAAAAGCATTACTGCGGCAGAAAGCTTGACGGCAGGTCTCTTTCAAGCGACAT
TAGCAGACTTTTCGGGCGTTTCAGCAATCTTTAATGGCGGTTTTGTCACTTACAGTTTAGAAGAAAAGTCTAAGATGTTG
GATATTTCCGAGCAAGAGCTAAAAGAACACGGGGTCGTTTCTGAGTTTACGGCTCGAAAAATGGCAGAGCAGGCACGGCT
CAAGACTCAGTCTGATTATGGAGTCAGTCTGACAGGTGTAGCTGGGCCAGATAGCCTAGAGGGGCATCCAGCTGGCACAG
TTTTTATTGGACTGGCACATGCAAAAGGGACAGAAGTGATCAAGGCTAATATCGCAGGACGGAGTCGAGCAGATGTACGT
CACATCGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGACTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(262-415)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F2D2E5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

89.952

100

0.9
  cinA Streptococcus pneumoniae TIGR4

89.713

100

0.897
  cinA Streptococcus pneumoniae Rx1

89.713

100

0.897
  cinA Streptococcus pneumoniae R6

89.713

100

0.897
  cinA Streptococcus pneumoniae D39

89.474

100

0.895
  cinA Streptococcus mitis NCTC 12261

88.995

100

0.89
  cinA Streptococcus mutans UA159

71.053

100

0.711
  cinA Streptococcus suis isolate S10

55.288

99.522

0.55
  cinA Bacillus subtilis subsp. subtilis str. 168

45.215

100

0.452

Multiple sequence alignment