Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   EL140_RS00830 Genome accession   NZ_LR134336
Coordinates   153378..154394 (+) Length   338 a.a.
NCBI ID   WP_002875106.1    Uniprot ID   -
Organism   Streptococcus oralis ATCC 35037 strain NCTC 11427     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 148378..159394
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL140_RS00810 (NCTC11427_00155) - 148795..150612 (+) 1818 WP_001220886.1 acyltransferase family protein -
  EL140_RS00815 (NCTC11427_00156) nagA 150753..151904 (+) 1152 WP_001134442.1 N-acetylglucosamine-6-phosphate deacetylase -
  EL140_RS00820 (NCTC11427_00157) - 152062..152427 (+) 366 WP_000286399.1 DUF1033 family protein -
  EL140_RS00825 (NCTC11427_00158) comGA/cglA/cilD 152489..153430 (+) 942 WP_000249583.1 competence type IV pilus ATPase ComGA Machinery gene
  EL140_RS00830 (NCTC11427_00159) comGB/cglB 153378..154394 (+) 1017 WP_002875106.1 competence type IV pilus assembly protein ComGB Machinery gene
  EL140_RS00835 (NCTC11427_00160) comGC/cglC 154396..154719 (+) 324 WP_000735794.1 competence type IV pilus major pilin ComGC Machinery gene
  EL140_RS00840 (NCTC11427_00161) comGD/cglD 154682..155116 (+) 435 WP_001180060.1 competence type IV pilus minor pilin ComGD Machinery gene
  EL140_RS00845 (NCTC11427_00162) comGE/cglE 155079..155381 (+) 303 WP_000413369.1 competence type IV pilus minor pilin ComGE Machinery gene
  EL140_RS00850 (NCTC11427_00163) comGF/cglF 155344..155805 (+) 462 WP_002875275.1 competence type IV pilus minor pilin ComGF Machinery gene
  EL140_RS00855 (NCTC11427_00164) comGG/cglG 155783..156196 (+) 414 WP_000265647.1 competence type IV pilus minor pilin ComGG Machinery gene
  EL140_RS00860 (NCTC11427_00165) - 156229..156816 (+) 588 WP_000679790.1 class I SAM-dependent methyltransferase -
  EL140_RS00865 (NCTC11427_00166) comYH 156877..157830 (+) 954 WP_000345144.1 class I SAM-dependent methyltransferase Machinery gene
  EL140_RS00870 (NCTC11427_00167) - 157882..159072 (+) 1191 WP_000167789.1 acetate kinase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38657.80 Da        Isoelectric Point: 9.6790

>NTDB_id=1121813 EL140_RS00830 WP_002875106.1 153378..154394(+) (comGB/cglB) [Streptococcus oralis ATCC 35037 strain NCTC 11427]
MDISQVFRLKRKKLATAKQKKIITLFNNLFSSGFHLVEIISFLGRSALLEKDYVAQMHQGLSQGKSFSEMMESLGFSSAI
VTQLSLAEVHGNLHLSLRKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
LGLVLVCSLSLLLALTFYKRSSKMRVFSMLARVPFLGIFVQTYLTAYYAREWGNMISQGMELTQIFQIMQEQGSQLFKEI
GQDLAQALQNGREFSQTITTYPFFKKELSLIIEYGEVKSKLGSELEIYAEKTWESFFIRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=1121813 EL140_RS00830 WP_002875106.1 153378..154394(+) (comGB/cglB) [Streptococcus oralis ATCC 35037 strain NCTC 11427]
ATGGACATATCACAAGTCTTCAGGCTGAAACGGAAAAAATTAGCTACAGCTAAGCAGAAGAAAATCATCACTTTGTTTAA
CAACCTCTTCTCCAGTGGCTTTCATTTGGTGGAAATTATTTCTTTTTTGGGCAGAAGTGCCTTGCTGGAAAAGGACTATG
TGGCCCAGATGCACCAAGGATTGTCTCAGGGGAAATCCTTTTCAGAAATGATGGAAAGTTTGGGCTTTTCAAGTGCCATT
GTGACCCAATTATCTCTAGCTGAAGTACATGGAAATCTTCACCTGAGTCTGAGGAAGATAGAAGAATATCTGGATAATTT
GGCCAAGGTCAAGAAAAAGTTAATCGAAGTGGCGACTTATCCCCTGATTTTGCTGGGATTTCTCCTGCTAATCATGCTGG
GGTTGAGAAACTATCTACTTCCCCAACTGGACAGTAGCAATATTGCCACTCAAATCATCGGCAATCTGCCACAAATATTT
CTGGGACTAGTGCTGGTTTGCTCTCTATCTTTACTTTTAGCCCTCACTTTCTACAAAAGAAGTTCCAAGATGCGGGTTTT
CTCGATGTTGGCACGGGTTCCCTTTCTAGGAATCTTTGTCCAGACCTATCTGACGGCCTATTACGCGCGTGAATGGGGCA
ATATGATTTCACAGGGGATGGAGCTGACGCAAATTTTTCAGATCATGCAGGAACAAGGTTCTCAGCTCTTTAAAGAAATC
GGTCAAGATTTGGCTCAAGCCCTGCAAAATGGCCGCGAATTTTCTCAAACCATAACGACCTATCCTTTCTTTAAGAAGGA
GTTGAGTCTCATCATCGAGTATGGGGAAGTCAAGTCCAAGCTGGGGAGTGAGTTGGAAATCTACGCGGAAAAGACTTGGG
AATCCTTTTTTATCCGAGTCAACCGCACCATGAACTTAGTACAGCCACTGGTTTTTATCTTTGTGGCCCTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus mitis SK321

92.899

100

0.929
  comGB/cglB Streptococcus mitis NCTC 12261

92.308

100

0.923
  comGB/cglB Streptococcus pneumoniae Rx1

90.828

100

0.908
  comGB/cglB Streptococcus pneumoniae D39

90.828

100

0.908
  comGB/cglB Streptococcus pneumoniae R6

90.828

100

0.908
  comGB/cglB Streptococcus pneumoniae TIGR4

90.828

100

0.908
  comYB Streptococcus gordonii str. Challis substr. CH1

73.512

99.408

0.731
  comYB Streptococcus mutans UA140

59.248

94.379

0.559
  comYB Streptococcus mutans UA159

59.248

94.379

0.559
  comGB Lactococcus lactis subsp. cremoris KW2

52.663

100

0.527

Multiple sequence alignment