Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   EL133_RS00250 Genome accession   NZ_LR134323
Coordinates   50348..51607 (+) Length   419 a.a.
NCBI ID   WP_006740047.1    Uniprot ID   -
Organism   Streptococcus urinalis strain NCTC13766     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 45348..56607
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL133_RS00230 (NCTC13766_00047) mutL 46646..48616 (+) 1971 WP_006739521.1 DNA mismatch repair endonuclease MutL -
  EL133_RS00235 (NCTC13766_00048) ruvA 49085..49678 (+) 594 WP_006739095.1 Holliday junction branch migration protein RuvA -
  EL133_RS00240 (NCTC13766_00049) - 49687..50251 (+) 565 Protein_46 DNA-3-methyladenine glycosylase I -
  EL133_RS00250 (NCTC13766_00050) cinA 50348..51607 (+) 1260 WP_006740047.1 competence/damage-inducible protein A Machinery gene
  EL133_RS00255 (NCTC13766_00051) recA 51677..52819 (+) 1143 WP_006739035.1 recombinase RecA Machinery gene
  EL133_RS00260 (NCTC13766_00052) spx 53028..53426 (+) 399 WP_006739023.1 transcriptional regulator Spx -
  EL133_RS00265 (NCTC13766_00053) - 53551..53820 (+) 270 WP_006738453.1 IreB family regulatory phosphoprotein -
  EL133_RS00270 (NCTC13766_00054) ruvX 53817..54236 (+) 420 WP_006740248.1 Holliday junction resolvase RuvX -
  EL133_RS00275 (NCTC13766_00055) - 54246..54557 (+) 312 WP_006739290.1 DUF1292 domain-containing protein -
  EL133_RS00280 (NCTC13766_00056) - 54785..56344 (+) 1560 WP_006739923.1 hypothetical protein -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 46009.81 Da        Isoelectric Point: 7.8598

>NTDB_id=1121501 EL133_RS00250 WP_006740047.1 50348..51607(+) (cinA) [Streptococcus urinalis strain NCTC13766]
MKAEIIAVGTEILTGQIVNTNAQFLSEKMAELGIDIYFQTVVGDNETRLLSVIELASKRSDLIILCGGLGPTEDDLTKQT
LAKYLNKQLVFDEEANQKLDAFFASRDQFSRTPNNERQAQLIEGSIPLQNRTGLAVGGIITSSDRQYVVLPGPPSELKPM
VNEQLIPHLSKSNTKLYSRVLRFFGIGESQLATILSDFIENQTDPTLAPYAKIGEVTLRMSTKAINQVEATKKLEALEGK
LLATKTLDNKYLSDFFYGYGENNSLPEVVFNLLKESHTTISVAESLTAGLFQSTLADFPGVSKLFFGGFITYSLKEKSKM
LSINKKELEKHGVVSAYTAEKMASQARLLTKTDIGVSLTGVAGPESLEGHKAGTVFIGIATKEKTVSYKVNVGNRTRSDI
RYIACLNAFNLVRKTLLNL

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=1121501 EL133_RS00250 WP_006740047.1 50348..51607(+) (cinA) [Streptococcus urinalis strain NCTC13766]
ATGAAAGCAGAAATTATTGCAGTTGGTACAGAGATTTTAACAGGACAAATTGTAAATACAAATGCTCAGTTTTTATCAGA
AAAGATGGCTGAACTAGGTATTGATATTTATTTTCAAACTGTTGTTGGTGACAATGAGACAAGATTACTGTCGGTTATTG
AACTAGCGAGCAAAAGGAGTGACCTCATTATACTATGTGGTGGCTTAGGCCCAACAGAAGATGACTTGACAAAACAAACA
CTAGCTAAATACTTAAATAAACAATTAGTTTTTGATGAAGAAGCTAATCAAAAATTGGATGCATTTTTCGCTAGTAGAGA
TCAGTTTAGCAGAACACCTAACAATGAAAGACAAGCTCAATTAATAGAAGGGTCAATTCCTCTTCAAAATCGTACAGGAC
TAGCTGTCGGTGGCATAATTACATCATCAGATAGACAATATGTTGTATTGCCTGGACCCCCTAGTGAATTAAAACCAATG
GTTAATGAACAATTGATTCCTCATTTATCAAAATCAAATACTAAACTCTATTCTAGAGTCTTACGATTCTTCGGTATTGG
TGAAAGTCAATTAGCTACAATTTTATCTGACTTTATTGAAAATCAAACAGATCCAACATTAGCACCCTATGCAAAGATTG
GTGAAGTCACTTTACGGATGTCTACTAAAGCAATTAATCAAGTTGAAGCTACTAAAAAGCTTGAGGCATTAGAAGGTAAA
CTATTAGCTACTAAAACACTAGACAATAAGTATCTATCTGATTTCTTTTATGGTTACGGTGAAAATAATTCTTTACCTGA
AGTTGTCTTTAATCTTTTAAAAGAATCTCATACCACTATTTCAGTTGCAGAAAGTTTGACAGCAGGACTATTTCAGTCAA
CATTAGCCGATTTCCCAGGGGTATCTAAACTATTTTTTGGTGGGTTTATCACTTATAGTTTAAAAGAAAAATCAAAAATG
CTTTCTATTAATAAAAAAGAGTTAGAAAAACATGGTGTTGTAAGTGCCTATACAGCTGAAAAAATGGCAAGTCAAGCAAG
GTTATTAACAAAAACGGATATTGGTGTTAGTTTAACTGGTGTGGCTGGGCCAGAATCATTAGAAGGTCATAAAGCAGGAA
CTGTTTTTATTGGCATTGCGACAAAAGAAAAGACTGTATCTTATAAAGTAAATGTTGGAAATAGAACACGCTCAGACATA
CGCTATATAGCTTGTTTAAACGCATTTAATCTAGTCCGAAAAACTTTATTAAATCTTTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(263-416)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-240)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

68.182

99.761

0.68
  cinA Streptococcus mitis SK321

67.703

99.761

0.675
  cinA Streptococcus mitis NCTC 12261

67.703

99.761

0.675
  cinA Streptococcus pneumoniae TIGR4

66.986

99.761

0.668
  cinA Streptococcus pneumoniae Rx1

66.986

99.761

0.668
  cinA Streptococcus pneumoniae R6

66.986

99.761

0.668
  cinA Streptococcus pneumoniae D39

66.746

99.761

0.666
  cinA Streptococcus suis isolate S10

53.333

100

0.535
  cinA Bacillus subtilis subsp. subtilis str. 168

45.694

99.761

0.456

Multiple sequence alignment