Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   EL084_RS08440 Genome accession   NZ_LR134292
Coordinates   1683283..1684542 (-) Length   419 a.a.
NCBI ID   WP_126440801.1    Uniprot ID   -
Organism   Streptococcus equinus strain NCTC10389     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1678283..1689542
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL084_RS08410 (NCTC10389_01767) - 1678372..1679949 (-) 1578 WP_126440799.1 DUF2079 domain-containing protein -
  EL084_RS09400 (NCTC10389_01768) - 1679992..1680120 (-) 129 WP_021143294.1 hypothetical protein -
  EL084_RS08415 (NCTC10389_01769) - 1680219..1680536 (-) 318 WP_004233505.1 DUF1292 domain-containing protein -
  EL084_RS08420 (NCTC10389_01770) ruvX 1680569..1680988 (-) 420 WP_004233508.1 Holliday junction resolvase RuvX -
  EL084_RS08425 (NCTC10389_01771) - 1680985..1681254 (-) 270 WP_004233510.1 IreB family regulatory phosphoprotein -
  EL084_RS08430 (NCTC10389_01772) spx 1681484..1681882 (-) 399 WP_004233512.1 transcriptional regulator Spx -
  EL084_RS08435 (NCTC10389_01773) recA 1682079..1683233 (-) 1155 WP_004233517.1 recombinase RecA Machinery gene
  EL084_RS08440 (NCTC10389_01774) cinA 1683283..1684542 (-) 1260 WP_126440801.1 competence/damage-inducible protein A Machinery gene
  EL084_RS08445 (NCTC10389_01775) - 1684655..1685857 (-) 1203 WP_126440934.1 MFS transporter -
  EL084_RS08450 (NCTC10389_01776) - 1685980..1686537 (-) 558 WP_044023434.1 DNA-3-methyladenine glycosylase I -
  EL084_RS08455 (NCTC10389_01777) ruvA 1686567..1687160 (-) 594 WP_126440803.1 Holliday junction branch migration protein RuvA -
  EL084_RS08460 (NCTC10389_01778) mutL 1687161..1689104 (-) 1944 WP_115255541.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45598.94 Da        Isoelectric Point: 4.8309

>NTDB_id=1120466 EL084_RS08440 WP_126440801.1 1683283..1684542(-) (cinA) [Streptococcus equinus strain NCTC10389]
MKAEIIAVGTEILTGQITNTNAQFLSEEFAKLGIDVFFQTAVGDNEERLLSIIDLASKRSDLVVLCGGLGPTEDDLTKQT
LAKYLGRNLVFDEQASKRLDEFFATRPQFTRTANNEHQAQLIEGSTPLQNSTGLAVGGVLEVDGVTYVVLPGPPSELKPM
VWDYLVPLLSSDHKQLYSRVLRFFGIGESQLVTVLSDLIENQTDPTIAPYAKTGEVTLRLSTKADDLEAAKAKLDELEHK
ILAKNTLNSIPLENLLYGYGDDNSMARVVFDLLKQKHKTITAAESLTAGLFQSSIADFPGSSAVFNGGFVTYSIEEKAKM
LQIPLKDLQEHGVVSHFTAEKMAEQSRLLTDADFGIGLTGVAGPDGLEGHPAGTVFIGIATKEKVQSIRVIIGGRSRSDV
RHIACLYAFNLVRQALLQD

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=1120466 EL084_RS08440 WP_126440801.1 1683283..1684542(-) (cinA) [Streptococcus equinus strain NCTC10389]
ATGAAAGCTGAAATTATTGCTGTTGGAACAGAGATTTTAACAGGACAAATCACAAATACGAATGCACAATTTCTATCAGA
GGAATTTGCTAAGTTAGGGATTGATGTCTTTTTCCAAACAGCAGTTGGAGACAATGAAGAACGTCTGCTGTCTATCATTG
ATTTGGCAAGTAAACGCAGTGATTTAGTTGTTCTTTGCGGTGGTTTAGGACCAACCGAAGATGATTTAACAAAACAAACT
TTGGCAAAATATCTAGGACGTAACTTGGTTTTTGATGAACAGGCAAGTAAACGTTTGGATGAATTCTTTGCAACACGTCC
GCAATTTACAAGAACAGCTAATAATGAACATCAGGCTCAATTGATTGAAGGATCAACACCTCTTCAAAATAGTACTGGAC
TTGCTGTAGGTGGTGTTCTGGAAGTTGATGGTGTTACTTATGTCGTTCTTCCTGGACCACCAAGTGAATTGAAGCCTATG
GTTTGGGACTATTTAGTGCCATTGCTATCTAGTGACCACAAGCAATTGTATTCACGTGTCTTACGTTTCTTTGGTATCGG
GGAAAGTCAGTTGGTAACTGTTTTGTCAGATTTGATTGAAAATCAAACAGACCCAACAATCGCTCCATATGCCAAAACAG
GTGAAGTAACACTTAGATTGTCAACGAAGGCTGATGACCTTGAAGCAGCTAAGGCTAAGTTGGATGAGCTTGAGCATAAG
ATTCTGGCTAAGAATACTTTAAATAGTATTCCGCTTGAAAATTTGCTTTATGGATACGGTGATGATAATAGTATGGCGCG
TGTTGTTTTTGATTTACTTAAGCAAAAACATAAAACTATTACGGCTGCAGAAAGTTTGACAGCTGGTCTGTTTCAATCAA
GTATTGCTGATTTTCCAGGCTCTTCAGCAGTTTTTAATGGTGGTTTTGTGACTTATAGCATTGAAGAAAAGGCAAAAATG
CTTCAAATCCCTTTAAAAGATTTACAAGAACATGGGGTTGTGAGTCATTTTACAGCTGAAAAAATGGCTGAGCAGTCACG
ATTGCTGACAGACGCTGATTTTGGAATTGGCTTAACAGGAGTTGCTGGTCCAGATGGTCTAGAAGGTCATCCAGCGGGAA
CAGTTTTCATAGGTATTGCTACAAAAGAAAAAGTTCAGTCTATCCGTGTCATTATAGGTGGACGAAGCCGTTCAGATGTG
CGTCATATTGCATGTTTGTATGCTTTTAACTTAGTACGTCAAGCTTTATTACAAGACTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(263-415)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

71.942

99.523

0.716
  cinA Streptococcus mitis SK321

71.122

100

0.711
  cinA Streptococcus mitis NCTC 12261

70.406

100

0.704
  cinA Streptococcus pneumoniae Rx1

69.212

100

0.692
  cinA Streptococcus pneumoniae TIGR4

69.212

100

0.692
  cinA Streptococcus pneumoniae R6

69.212

100

0.692
  cinA Streptococcus pneumoniae D39

68.974

100

0.69
  cinA Streptococcus suis isolate S10

53.606

99.284

0.532
  cinA Bacillus subtilis subsp. subtilis str. 168

45.238

100

0.453

Multiple sequence alignment