Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   EL078_RS08905 Genome accession   NZ_LR134282
Coordinates   1790904..1792163 (-) Length   419 a.a.
NCBI ID   WP_074483864.1    Uniprot ID   -
Organism   Streptococcus equinus strain NCTC8140     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1785904..1797163
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL078_RS08875 (NCTC8140_01800) - 1785992..1787569 (-) 1578 WP_126438159.1 DUF2079 domain-containing protein -
  EL078_RS09445 (NCTC8140_01801) - 1787612..1787740 (-) 129 WP_267878376.1 hypothetical protein -
  EL078_RS08880 (NCTC8140_01802) - 1787839..1788156 (-) 318 WP_006531413.1 DUF1292 domain-containing protein -
  EL078_RS08885 (NCTC8140_01803) ruvX 1788189..1788608 (-) 420 WP_004233508.1 Holliday junction resolvase RuvX -
  EL078_RS08890 (NCTC8140_01804) - 1788605..1788874 (-) 270 WP_004233510.1 IreB family regulatory phosphoprotein -
  EL078_RS08895 (NCTC8140_01805) spx 1789104..1789502 (-) 399 WP_004233512.1 transcriptional regulator Spx -
  EL078_RS08900 (NCTC8140_01806) recA 1789700..1790854 (-) 1155 WP_004233517.1 recombinase RecA Machinery gene
  EL078_RS08905 (NCTC8140_01807) cinA 1790904..1792163 (-) 1260 WP_074483864.1 competence/damage-inducible protein A Machinery gene
  EL078_RS08910 (NCTC8140_01808) - 1792277..1793479 (-) 1203 WP_033153546.1 MFS transporter -
  EL078_RS08915 (NCTC8140_01809) - 1793602..1794159 (-) 558 WP_164554336.1 DNA-3-methyladenine glycosylase I -
  EL078_RS08920 (NCTC8140_01810) ruvA 1794189..1794782 (-) 594 WP_024344431.1 Holliday junction branch migration protein RuvA -
  EL078_RS08925 (NCTC8140_01811) mutL 1794783..1796726 (-) 1944 WP_027968297.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45613.05 Da        Isoelectric Point: 5.0735

>NTDB_id=1120003 EL078_RS08905 WP_074483864.1 1790904..1792163(-) (cinA) [Streptococcus equinus strain NCTC8140]
MKAEIIAVGTEILTGQITNTNAQFLSEEFAKLGIDVFFQTAVGDNEERLLSIIALASKRSDLVVLCGGLGPTEDDLTKQT
LAKYLGRNLVFDEQASKRLDEFFATRPQFTRTANNERQAQLIEGSTPLQNSTGLAVGGVLEVDGVTYVVLPGPPSELKPM
VWDYLVPLLSSDHKQLYSRVLRFFGIGESQLVTVLSDLIENQTDPTIAPYAKTGEVTLRLSTKADDLETAKAKLDELEHK
ILAKKTLNSIPLENLLYGYGDDNSMARVVFDLLKQKHKTITAAESLTAGLFQSSIADFPGSSAVFNGGFVTYSIEEKAKM
LQIPLKDLQEHGVVSHFTAEKMAEQSRLLTDADFGIGLTGVAGPDGLEGHPAGTVFIGIATKEKVHSIRVVIGGRSRSDV
RHIACLYAFNLVRQALLQD

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=1120003 EL078_RS08905 WP_074483864.1 1790904..1792163(-) (cinA) [Streptococcus equinus strain NCTC8140]
ATGAAAGCTGAAATCATTGCTGTTGGAACAGAGATTTTAACAGGACAAATCACAAATACAAATGCACAATTTCTATCAGA
GGAATTTGCTAAGTTAGGGATTGATGTCTTTTTCCAAACGGCAGTTGGGGACAATGAAGAACGTCTGCTGTCTATCATTG
CTTTGGCAAGTAAGCGCAGTGATTTAGTTGTTCTTTGCGGTGGTTTAGGACCAACCGAAGATGATTTAACAAAACAAACT
TTGGCAAAATATCTAGGACGTAACTTGGTTTTTGATGAACAGGCAAGTAAACGTTTGGATGAATTCTTTGCGACACGTCC
GCAATTTACAAGAACAGCTAACAATGAACGTCAGGCTCAATTGATTGAGGGGTCAACACCTCTTCAAAATAGTACGGGAC
TTGCTGTAGGTGGTGTTCTGGAAGTTGATGGTGTTACTTATGTCGTTCTTCCTGGACCACCAAGTGAATTGAAGCCTATG
GTTTGGGACTATTTAGTGCCATTGCTATCTAGTGACCACAAGCAATTGTATTCACGTGTCTTACGTTTCTTTGGTATCGG
GGAAAGTCAGTTGGTAACAGTTTTATCAGATTTGATTGAAAATCAAACAGACCCAACAATCGCTCCGTATGCCAAAACAG
GTGAAGTGACACTTAGACTGTCAACGAAAGCTGATGACCTTGAAACAGCTAAGGCTAAGTTGGATGAGCTTGAGCATAAG
ATTCTTGCTAAGAAGACTTTAAATAGTATTCCGCTTGAAAATTTGCTTTATGGATACGGTGATGATAATAGTATGGCGCG
TGTTGTTTTTGATTTACTTAAGCAAAAACATAAGACTATTACGGCTGCAGAAAGTTTGACAGCTGGTCTGTTTCAATCAA
GTATTGCTGATTTTCCAGGCTCTTCAGCAGTTTTTAATGGTGGTTTTGTGACTTATAGCATTGAAGAAAAGGCAAAAATG
CTTCAAATTCCTTTAAAAGATTTACAAGAACATGGGGTTGTGAGTCATTTTACAGCTGAAAAAATGGCTGAGCAGTCACG
ATTGCTGACAGATGCTGATTTTGGAATTGGCTTAACAGGAGTTGCTGGTCCAGATGGTCTAGAAGGTCATCCAGCGGGAA
CAGTTTTCATAGGTATTGCTACAAAAGAAAAAGTTCATTCTATCCGTGTTGTTATAGGTGGACGAAGCCGTTCAGATGTG
CGTCATATTGCATGTTTGTATGCTTTTAACTTAGTACGTCAAGCTTTATTACAAGACTAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(263-415)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

72.182

99.523

0.718
  cinA Streptococcus mitis SK321

71.36

100

0.714
  cinA Streptococcus mitis NCTC 12261

70.644

100

0.706
  cinA Streptococcus pneumoniae Rx1

69.451

100

0.695
  cinA Streptococcus pneumoniae TIGR4

69.451

100

0.695
  cinA Streptococcus pneumoniae R6

69.451

100

0.695
  cinA Streptococcus pneumoniae D39

69.212

100

0.692
  cinA Streptococcus suis isolate S10

53.846

99.284

0.535
  cinA Bacillus subtilis subsp. subtilis str. 168

45.498

100

0.458

Multiple sequence alignment