Detailed information NTG0111999

Bioinformatically predicted

Overview

• Name: pilQ
• Type: Machinery gene
• Locus tag: LOA_RS05180
• Genome accession: NZ_CP004006
• Coordinates: 1055359..1057551 (+)
• Length: 730 a.a.
• NCBI ID: WP_025385435.1
• Uniprot ID: W0BDK0
• Organism: Legionella oakridgensis ATCC 33761 = DSM 21215
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1050359..1062551

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LOA_RS05155 (Loa_01151)	-	1050870..1051811 (-)	942	WP_025385431.1	hypothetical protein	-
LOA_RS05160 (Loa_01152)	pilM	1052116..1053174 (+)	1059	WP_025385432.1	type IV pilus assembly protein PilM	Machinery gene
LOA_RS05165 (Loa_01153)	-	1053412..1053879 (+)	468	WP_238551333.1	PilN domain-containing protein	-
LOA_RS05170 (Loa_01154)	pilO	1053872..1054471 (+)	600	WP_025385433.1	type 4a pilus biogenesis protein PilO	Machinery gene
LOA_RS05175 (Loa_01155)	-	1054519..1055076 (+)	558	WP_025385434.1	pilus assembly protein PilP	-
LOA_RS05180 (Loa_01156)	pilQ	1055359..1057551 (+)	2193	WP_025385435.1	type IV pilus secretin PilQ	Machinery gene
LOA_RS05185	aroK	1057758..1058284 (+)	527	Protein_1066	shikimate kinase AroK	-
LOA_RS05190 (Loa_01159)	aroB	1058271..1059379 (+)	1109	Protein_1067	3-dehydroquinate synthase	-
LOA_RS05195 (Loa_01161)	-	1059381..1060064 (+)	684	WP_025385436.1	ATP-binding protein	-
LOA_RS05200 (Loa_01162)	-	1060061..1060780 (+)	720	WP_148294869.1	SPOR domain-containing protein	-
LOA_RS05205 (Loa_01163)	pnuC	1060734..1061317 (-)	584	Protein_1070	nicotinamide riboside transporter PnuC	-
LOA_RS05210 (Loa_01166)	-	1061532..1061960 (+)	429	WP_025385438.1	universal stress protein	-

Sequence

Protein

• Length: 730 a.a.
• Molecular weight: 80009.25 Da
• Isoelectric Point: 9.0374

>NTDB_id=111999 LOA_RS05180 WP_025385435.1 1055359..1057551(+) (pilQ) [Legionella oakridgensis ATCC 33761 = DSM 21215]
MRRIIIVFLLLLTSCTALYAQDNALTAVKVTPMPDNRVRLDFQFAQPLAQMPASFITQKPPRLIVDFINSKNQLNASQVS
QTIEIGSLKQYKIVAVGDRLRVILDLLDSISYSGHVAGNVYTLMLRGKSQGLISKPKEVFVTNRPVNARYSITNIDFRGS
ENQGGRLIVNLSDAGIPIEVSQSGKKVMVDFNSTRLPQRLQKRFDVIDFHSPAQMITAEQDGKNAIITLLNKGDYGHFAY
QVNKQFIVDVFPLTAEEIQEAKLKKKVFTGKRISLNFQDIQIRAVLQLLAEFTGINIVVSNRVEGNITLRLNDVPWDQAL
DIILTTQGLDKRQVGNVILIDKADVFAARENEELQAQQAAKKLAPIRSELLQINYAKAADIATMLKDKDNSLLSDRGTLS
VDTRTNTIWLQDTGAQIDEIRELVKQLDVPVKQVLIEARIVNVTKDCAEDIGVRFGVSRPTHLSGTLEGANALAGGTPAA
EVPIPDRLNVDLGALPIDASPASVGIALAKLGNGVLLDLELSALESEGRAEIIASPRLMTTNQQAAVIESGEDIPYQEAT
SSGATAVAFKKAVLSLKVTPQITPDGKLLMDLQINQDSDSGRRVQGVPIILTKSIETNVLVNNGQTIVLGGIYKQDTNNS
ITRVPFLGELPVVGNLFSRSQARTNNEELLIFITPRIITNNLSITTIEGPQQRFARGVELDKFGKPVAPMQVVEPPLPAK
AIVPIRPWKR

Nucleotide

• Length: 2193 bp

>NTDB_id=111999 LOA_RS05180 WP_025385435.1 1055359..1057551(+) (pilQ) [Legionella oakridgensis ATCC 33761 = DSM 21215]
TTGCGCAGAATTATTATTGTATTTTTATTACTTTTAACAAGCTGTACCGCTCTCTATGCCCAAGATAATGCGCTGACGGC
GGTGAAAGTAACTCCCATGCCGGATAACCGGGTCCGTCTTGATTTTCAATTTGCGCAACCACTCGCCCAGATGCCTGCCA
GTTTCATTACTCAGAAGCCACCACGGTTGATTGTTGATTTTATTAACAGCAAAAATCAACTCAATGCGTCACAAGTCTCC
CAAACAATCGAAATAGGTTCTTTGAAGCAATATAAGATTGTTGCTGTTGGCGATCGCCTTAGAGTCATCTTGGACTTATT
GGATTCCATTTCTTATTCAGGTCATGTTGCCGGCAATGTCTATACACTGATGCTGCGAGGAAAAAGCCAGGGACTTATTT
CAAAGCCTAAAGAAGTATTTGTAACCAATCGGCCGGTTAATGCACGCTACAGCATTACTAATATTGATTTTCGCGGCAGT
GAAAATCAGGGAGGACGGCTTATTGTCAATTTGTCCGATGCTGGTATTCCCATTGAAGTCAGTCAATCTGGAAAAAAAGT
GATGGTTGACTTTAACAGTACCCGGCTGCCACAACGTCTGCAAAAGCGCTTTGATGTGATTGATTTTCACAGTCCTGCCC
AGATGATTACTGCCGAACAGGATGGTAAAAATGCTATAATTACCTTGTTAAATAAAGGGGATTATGGTCATTTTGCTTAT
CAGGTTAATAAACAATTTATTGTGGATGTATTTCCTCTTACTGCTGAAGAAATACAGGAAGCAAAATTAAAGAAAAAAGT
ATTTACCGGTAAACGAATTTCTTTAAATTTCCAAGATATTCAAATACGTGCGGTTTTACAGCTATTGGCTGAATTTACCG
GGATAAATATTGTGGTTAGTAATCGGGTGGAAGGCAACATTACCTTACGGCTGAATGATGTGCCTTGGGATCAGGCGCTG
GATATTATTTTGACCACTCAAGGTCTTGATAAGCGGCAAGTAGGAAATGTGATTTTAATTGATAAAGCAGACGTGTTTGC
TGCTCGGGAGAATGAAGAATTGCAGGCGCAGCAGGCTGCAAAAAAATTAGCACCTATTCGTTCGGAATTGCTGCAAATTA
ATTATGCTAAGGCAGCGGATATCGCAACCATGCTTAAGGATAAAGATAATTCTTTATTATCCGATCGTGGTACTTTAAGT
GTGGATACCAGGACCAATACCATTTGGTTGCAGGATACAGGTGCACAAATTGATGAAATAAGGGAGCTTGTTAAACAATT
AGACGTGCCAGTTAAACAAGTTTTGATTGAGGCACGTATTGTGAATGTCACTAAAGACTGTGCTGAAGACATTGGAGTCC
GCTTTGGTGTCTCAAGGCCAACGCATTTAAGTGGTACACTGGAGGGTGCCAACGCCTTGGCTGGAGGAACTCCAGCGGCG
GAAGTGCCTATTCCCGATCGTTTAAACGTCGATCTTGGAGCGTTGCCTATTGATGCTTCGCCAGCCTCAGTTGGGATTGC
GTTGGCAAAATTGGGAAATGGTGTATTACTGGATTTGGAATTATCCGCCTTGGAAAGTGAGGGGCGTGCCGAGATTATTG
CTAGCCCACGTTTGATGACAACCAATCAACAGGCTGCCGTGATTGAGTCCGGTGAAGATATTCCCTATCAGGAAGCAACT
TCTAGCGGAGCAACGGCAGTAGCCTTTAAAAAGGCGGTGCTGAGTTTGAAAGTAACACCGCAAATTACACCGGATGGCAA
ACTGTTAATGGATTTGCAAATTAATCAGGATTCAGATTCTGGCAGGCGAGTTCAGGGTGTTCCTATTATTTTAACCAAAT
CCATTGAAACCAATGTGCTGGTTAATAATGGTCAAACCATTGTTTTAGGAGGAATTTATAAACAAGACACAAATAATTCC
ATTACGCGCGTTCCATTTTTAGGGGAATTGCCTGTGGTGGGAAATTTATTTAGTCGCAGCCAGGCAAGAACGAATAATGA
GGAGTTGCTCATTTTCATTACTCCTAGGATAATAACCAACAATTTGTCGATTACAACCATAGAAGGGCCACAACAGCGTT
TTGCCCGTGGCGTAGAGCTGGACAAATTCGGCAAGCCGGTTGCTCCCATGCAGGTCGTAGAGCCACCGCTTCCAGCAAAA
GCGATTGTTCCAATAAGGCCATGGAAGCGTTGA

Domains

Predicted by InterproScan.

• Secretin and TonB N terminus short domain (STN) (295-340)

• AMIN domain (AMIN) (41-112)

• Bacterial type II and III secretion system protein (Secretin) (523-678)

• Bacterial type II/III secretion system short domain (Secretin_N) (370-433)

3D structure

• AlphaFold DB: W0BDK0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilQ	Legionella pneumophila strain ERS1305867	70.562	92.603	0.653
pilQ	Legionella pneumophila strain Lp02	70.414	92.603	0.652
pilQ	Pseudomonas aeruginosa PAK	38.408	98.082	0.377
comQ	Acinetobacter baylyi ADP1	37.621	99.041	0.373
pilQ	Acinetobacter baumannii strain A118	36.167	100	0.367
pilQ	Acinetobacter baumannii D1279779	36.167	100	0.367