Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   EL086_RS00345 Genome accession   NZ_LR134274
Coordinates   59861..61129 (+) Length   422 a.a.
NCBI ID   WP_014633777.1    Uniprot ID   A0AB33ZAN6
Organism   Streptococcus salivarius strain NCTC8618     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 54861..66129
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL086_RS00315 (NCTC8618_02477) - 55188..55625 (-) 438 WP_038675015.1 LytTR family DNA-binding domain-containing protein -
  EL086_RS00320 (NCTC8618_02478) - 55804..56106 (+) 303 WP_038675017.1 hypothetical protein -
  EL086_RS00325 (NCTC8618_02479) mutL 56159..58102 (+) 1944 WP_038675019.1 DNA mismatch repair endonuclease MutL -
  EL086_RS00330 (NCTC8618_02480) - 58233..58454 (+) 222 WP_038675022.1 hypothetical protein -
  EL086_RS00335 (NCTC8618_02481) ruvA 58611..59201 (+) 591 WP_002886323.1 Holliday junction branch migration protein RuvA -
  EL086_RS00340 (NCTC8618_02482) - 59210..59764 (+) 555 WP_002886325.1 DNA-3-methyladenine glycosylase I -
  EL086_RS00345 (NCTC8618_02483) cinA 59861..61129 (+) 1269 WP_014633777.1 competence/damage-inducible protein A Machinery gene
  EL086_RS00350 (NCTC8618_02484) recA 61165..62304 (+) 1140 WP_002886327.1 recombinase RecA Machinery gene
  EL086_RS00355 (NCTC8618_02485) spx 62472..62870 (+) 399 WP_002886328.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 422 a.a.        Molecular weight: 45663.89 Da        Isoelectric Point: 5.3215

>NTDB_id=1119791 EL086_RS00345 WP_014633777.1 59861..61129(+) (cinA) [Streptococcus salivarius strain NCTC8618]
MKAELIAVGTEILTGQITNTNAQFLSEKLAELGIDVYFHTAVGDNESRLLSVLDQASQRSDLVILCGGLGPTEDDLTKQT
LAKFLGKELVFDEEASKKLDSFFATRPKHTRTPNNERQAQIVEGAIPLQNPTGLAVGGIITAQGVTYVVLPGPPSELKPM
VNQELIPALTENHSSLYSRVLRFFGVGESQLVTILKEFIVNQTDPTIAPYAKVGEVTLRLSTKASSQEEADQKLDVLEKQ
IRSTKTLDGKSLSDFIYGYGESNSLAFEAFRLLKHHGKTITAAESLTAGLFQATIADFSGASQVFKGGFVTYSIEEKAKM
LGIPLSQLEEHGVVSHFTAEKMAEGARAKTDSDYGIALTGVAGPDSLEGHPAGTVFIGIADRNQVRSIKVVIGGRSRSDV
RYISTLYAFNLVRQALLQEDII

Nucleotide


Download         Length: 1269 bp        

>NTDB_id=1119791 EL086_RS00345 WP_014633777.1 59861..61129(+) (cinA) [Streptococcus salivarius strain NCTC8618]
ATGAAAGCTGAATTGATTGCAGTAGGAACTGAAATCCTAACCGGGCAGATCACCAATACCAATGCCCAATTTTTATCTGA
GAAACTAGCTGAACTAGGAATTGACGTGTATTTTCACACAGCAGTAGGAGACAATGAAAGCCGCCTACTTTCAGTTCTTG
ATCAAGCCAGTCAGCGTAGTGATTTAGTCATACTTTGTGGTGGACTTGGCCCTACTGAGGACGACCTAACCAAGCAAACC
CTGGCTAAATTTTTAGGAAAAGAACTCGTTTTTGATGAGGAGGCTAGTAAAAAACTGGATAGTTTCTTTGCTACTCGTCC
TAAACACACACGAACGCCTAATAATGAACGTCAAGCACAAATTGTTGAGGGGGCTATTCCCTTGCAAAACCCGACAGGTC
TTGCAGTTGGAGGGATTATTACTGCTCAAGGGGTGACCTATGTAGTCTTACCTGGTCCACCAAGTGAACTCAAACCTATG
GTGAATCAAGAACTTATTCCAGCTCTTACTGAGAATCACTCAAGTCTTTATTCGAGAGTCCTAAGATTCTTTGGCGTTGG
AGAAAGTCAATTAGTGACTATTCTGAAAGAGTTTATTGTTAACCAAACAGATCCAACCATAGCTCCATACGCTAAAGTGG
GGGAAGTAACACTTCGCTTGTCAACGAAGGCTTCTTCGCAAGAAGAAGCAGATCAAAAACTAGATGTTTTAGAAAAACAA
ATTCGTTCGACTAAAACTCTAGATGGCAAATCCTTATCTGATTTCATTTATGGATATGGAGAGTCTAATAGTTTAGCCTT
TGAAGCTTTTCGTTTGCTTAAGCACCATGGCAAGACCATCACTGCAGCTGAAAGCCTAACAGCAGGTTTATTTCAGGCTA
CTATTGCTGATTTTTCAGGAGCCTCACAAGTATTTAAAGGTGGCTTTGTTACTTACAGCATTGAAGAAAAAGCTAAAATG
TTGGGTATTCCTTTGTCGCAACTAGAAGAACATGGTGTTGTCAGTCATTTTACTGCAGAAAAAATGGCTGAAGGTGCTCG
AGCTAAAACAGATAGCGATTATGGAATTGCACTTACCGGTGTAGCTGGACCAGATTCCTTAGAAGGACACCCAGCAGGTA
CGGTATTTATTGGTATTGCTGATAGGAATCAAGTAAGGTCAATCAAGGTTGTTATAGGTGGAAGAAGTCGTTCTGATGTT
AGATATATTAGTACCCTCTATGCCTTTAACCTAGTTCGCCAAGCTTTATTACAAGAAGACATAATTTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(264-415)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

75.418

99.289

0.749
  cinA Streptococcus mitis NCTC 12261

74.463

99.289

0.739
  cinA Streptococcus pneumoniae TIGR4

73.986

99.289

0.735
  cinA Streptococcus pneumoniae Rx1

73.747

99.289

0.732
  cinA Streptococcus pneumoniae R6

73.747

99.289

0.732
  cinA Streptococcus pneumoniae D39

73.508

99.289

0.73
  cinA Streptococcus mutans UA159

71.942

98.815

0.711
  cinA Streptococcus suis isolate S10

54.808

98.578

0.54
  cinA Bacillus subtilis subsp. subtilis str. 168

45.131

99.763

0.45

Multiple sequence alignment