Detailed information NTG1119593

Bioinformatically predicted

Overview

• Name: comE/comE2
• Type: Regulator
• Locus tag: EL081_RS09970
• Genome accession: NZ_LR134266
• Coordinates: 1993064..1993816 (-)
• Length: 250 a.a.
• NCBI ID: WP_126405015.1
• Uniprot ID: -
• Organism: Streptococcus viridans strain NCTC3166
• Function: activate transcription of early competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1988064..1998816

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL081_RS09950 (NCTC3166_01965)	-	1988508..1990130 (+)	1623	WP_006595336.1	ATP-binding cassette domain-containing protein	-
EL081_RS09955 (NCTC3166_01966)	-	1990184..1992781 (+)	2598	WP_185946478.1	YfhO family protein	-
EL081_RS09970 (NCTC3166_01969)	comE/comE2	1993064..1993816 (-)	753	WP_126405015.1	response regulator transcription factor	Regulator
EL081_RS10180 (NCTC3166_01970)	-	1993817..1995136 (-)	1320	WP_232011417.1	GHKL domain-containing protein	-
EL081_RS09980 (NCTC3166_01971)	-	1995136..1995279 (-)	144	WP_126405016.1	bacteriocin	-
EL081_RS09990 (NCTC3166_01973)	rlmH	1995639..1996118 (-)	480	WP_126405017.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
EL081_RS09995 (NCTC3166_01974)	htrA	1996321..1997499 (+)	1179	WP_126405018.1	S1C family serine protease	Regulator
EL081_RS10000 (NCTC3166_01975)	spo0J	1997565..1998326 (+)	762	WP_126405019.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 250 a.a.
• Molecular weight: 29426.18 Da
• Isoelectric Point: 8.4082

>NTDB_id=1119593 EL081_RS09970 WP_126405015.1 1993064..1993816(-) (comE/comE2) [Streptococcus viridans strain NCTC3166]
MNIVLLEDEISQQVRVEKHVKAIAEEEGLRLNIVSTSKITELKEYLTNGDFHQLFFLDIDIKGDEKAGIKAAQMIREVNP
FAIIAFITTKSEFATITYRYKVSALEFIEKTLNENLFKEKIRECILYLKKNVIENKNIVDFFEYSFKNMEIRVPYRDILY
IETTGVSHKLRLVGKNFQKEFLGTIKDILEKDVDNHFFSPNQSYLVNQRMIVSFDRRKRLLMLEEETTCPVSRTQVKRVE
ELLNKIQKKA

Nucleotide

• Length: 753 bp

>NTDB_id=1119593 EL081_RS09970 WP_126405015.1 1993064..1993816(-) (comE/comE2) [Streptococcus viridans strain NCTC3166]
ATGAATATTGTATTGCTAGAGGACGAAATTTCTCAACAAGTTCGAGTAGAGAAACATGTGAAAGCTATCGCTGAGGAGGA
AGGACTACGATTAAATATTGTTTCCACCAGTAAAATAACTGAATTAAAGGAATACCTAACCAATGGTGATTTTCATCAGC
TTTTCTTCCTTGATATTGATATCAAAGGGGATGAAAAAGCTGGCATCAAGGCAGCTCAAATGATTCGCGAGGTCAATCCT
TTTGCCATCATTGCCTTTATTACGACGAAATCGGAATTTGCTACCATTACTTATCGTTACAAGGTATCAGCTCTTGAATT
TATTGAAAAAACCTTGAATGAAAACTTGTTTAAAGAAAAAATTCGAGAATGCATTCTTTACTTGAAGAAGAATGTGATTG
AAAATAAAAATATCGTTGATTTCTTTGAGTATAGTTTCAAAAATATGGAAATTCGAGTGCCATATCGAGATATATTGTAC
ATTGAAACAACTGGAGTTTCCCACAAATTGCGACTTGTTGGAAAGAATTTTCAAAAGGAATTTTTAGGGACTATCAAGGA
TATACTTGAAAAAGATGTGGACAATCATTTCTTCAGTCCTAATCAGTCTTATCTAGTGAATCAAAGAATGATTGTCAGTT
TTGATCGTCGCAAGAGACTCTTGATGTTAGAAGAGGAGACAACTTGCCCTGTTTCTCGTACACAGGTGAAAAGGGTCGAA
GAATTATTAAATAAAATACAGAAAAAGGCTTGA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (151-243)

• Response regulator receiver domain (Response_reg) (18-121)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/comE2	Streptococcus gordonii strain NCTC7865	50.4	100	0.504
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	50.4	100	0.504
comE	Streptococcus infantis strain Atu-4	49.2	100	0.492
comE	Streptococcus mitis SK321	48	100	0.48
comE	Streptococcus mitis NCTC 12261	48	100	0.48
comE	Streptococcus pneumoniae Rx1	47.2	100	0.472
comE	Streptococcus pneumoniae D39	47.2	100	0.472
comE	Streptococcus pneumoniae R6	47.2	100	0.472
comE	Streptococcus pneumoniae TIGR4	47.2	100	0.472
comE/comE1	Streptococcus equinus JB1	37.805	98.4	0.372