Detailed information NTG1119594

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: EL081_RS09995
• Genome accession: NZ_LR134266
• Coordinates: 1996321..1997499 (+)
• Length: 392 a.a.
• NCBI ID: WP_126405018.1
• Uniprot ID: -
• Organism: Streptococcus viridans strain NCTC3166
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1991321..2002499

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL081_RS09970 (NCTC3166_01969)	comE/comE2	1993064..1993816 (-)	753	WP_126405015.1	response regulator transcription factor	Regulator
EL081_RS10180 (NCTC3166_01970)	-	1993817..1995136 (-)	1320	WP_232011417.1	GHKL domain-containing protein	-
EL081_RS09980 (NCTC3166_01971)	-	1995136..1995279 (-)	144	WP_126405016.1	bacteriocin	-
EL081_RS09990 (NCTC3166_01973)	rlmH	1995639..1996118 (-)	480	WP_126405017.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
EL081_RS09995 (NCTC3166_01974)	htrA	1996321..1997499 (+)	1179	WP_126405018.1	S1C family serine protease	Regulator
EL081_RS10000 (NCTC3166_01975)	spo0J	1997565..1998326 (+)	762	WP_126405019.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 392 a.a.
• Molecular weight: 41336.69 Da
• Isoelectric Point: 5.1173

>NTDB_id=1119594 EL081_RS09995 WP_126405018.1 1996321..1997499(+) (htrA) [Streptococcus viridans strain NCTC3166]
MKQPSNFLKKALQLLLVLVIGFTGGILGTLTSFQFTKGNSTNSSQEIKSTIVNRAYKNTTSTSEAVDKVKNAVVSVITYA
ETSEKGFINGETDTDPEVASEGSGVIYKKDGKDAYVVTNAHVLMGATEADILFADGNKVSGEVVGSDTFSDIAVVKISSD
NVTTVAEFGDSSKLTVGETAIAIGSPLGTKFANSVTQGIVSSLGRTVKLKSEDGQNVSTKALQTDAAINPGNSGGPLINI
QGQVIGITSSKISSNGQTAVEGMGFAIPVNDVQNIIEHLEKDGKVIRPALGITMMDLASLSSSDLSQLDIPSKLKGGVLV
RSVENDMPASKYLRRLDIITKIDDTTIESTADLQSALYSHQIGDKIKVIFYRDGKQKTATIELTKSTENLGN

Nucleotide

• Length: 1179 bp

>NTDB_id=1119594 EL081_RS09995 WP_126405018.1 1996321..1997499(+) (htrA) [Streptococcus viridans strain NCTC3166]
ATGAAACAACCATCAAATTTTCTAAAAAAAGCTTTGCAACTTTTGCTTGTTCTTGTCATTGGGTTTACTGGAGGAATCTT
AGGAACCTTAACCTCTTTCCAGTTTACCAAAGGGAATTCTACAAATTCTAGCCAAGAAATAAAATCTACCATAGTCAATC
GTGCTTATAAGAATACAACATCAACTAGTGAAGCCGTTGATAAGGTTAAAAATGCTGTTGTTTCTGTTATTACCTACGCT
GAAACCTCTGAAAAAGGCTTCATCAATGGAGAAACAGATACTGATCCAGAAGTAGCTAGTGAAGGTTCAGGTGTTATCTA
TAAAAAAGATGGGAAAGACGCTTATGTAGTAACCAATGCTCACGTGTTAATGGGAGCAACAGAAGCAGATATTCTCTTTG
CAGACGGAAATAAAGTTTCCGGAGAAGTTGTTGGTTCAGATACCTTCTCAGATATTGCGGTTGTCAAAATCAGTTCAGAC
AATGTTACGACCGTGGCTGAATTTGGAGATTCATCTAAGTTGACTGTCGGAGAGACCGCAATCGCTATTGGTAGTCCTTT
AGGGACAAAATTTGCCAATTCCGTTACCCAAGGGATTGTCTCTAGTCTCGGACGTACTGTGAAGCTCAAATCAGAAGACG
GCCAAAATGTGTCTACAAAAGCGTTGCAAACGGACGCTGCCATCAACCCAGGAAATTCTGGTGGTCCCCTTATCAATATT
CAGGGACAAGTCATCGGAATTACCTCAAGTAAAATCTCTTCAAATGGGCAAACTGCGGTTGAAGGAATGGGATTTGCTAT
TCCTGTAAATGATGTGCAAAATATTATTGAACATTTAGAAAAAGATGGTAAAGTCATTCGTCCAGCTCTTGGAATTACCA
TGATGGACCTGGCTAGCCTATCCTCTTCTGATCTTAGCCAATTAGACATTCCAAGCAAACTCAAAGGTGGGGTTCTTGTC
CGCTCAGTTGAAAATGATATGCCGGCATCCAAGTATTTACGTCGATTAGATATCATTACAAAAATCGATGATACAACCAT
TGAATCAACTGCGGATTTACAATCTGCCCTCTATTCTCATCAAATTGGTGATAAAATCAAAGTTATTTTCTATAGAGATG
GTAAGCAAAAAACAGCGACCATTGAGCTGACAAAATCTACAGAAAATCTTGGAAATTAA

Domains

Predicted by InterproScan.

• Peptidase family M50 (Peptidase_M50) (233-388)

• PDZ domain (PDZ_2) (288-383)

• Trypsin-like peptidase domain (Trypsin_2) (102-247)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mitis NCTC 12261	63.52	100	0.635
htrA	Streptococcus pneumoniae Rx1	63.265	100	0.633
htrA	Streptococcus pneumoniae D39	63.265	100	0.633
htrA	Streptococcus pneumoniae R6	63.265	100	0.633
htrA	Streptococcus pneumoniae TIGR4	63.265	100	0.633
htrA	Streptococcus gordonii str. Challis substr. CH1	62.183	100	0.625
htrA	Streptococcus mutans UA159	52.273	100	0.528