Detailed information    

insolico Bioinformatically predicted

Overview


Name   comGC   Type   Machinery gene
Locus tag   E0E15_RS08250 Genome accession   NZ_LR027870
Coordinates   1632504..1632815 (-) Length   103 a.a.
NCBI ID   WP_000472256.1    Uniprot ID   -
Organism   Staphylococcus aureus strain BPH2019 isolate BPH2019     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 1632984..1634156 1632504..1632815 flank 169


Gene organization within MGE regions


Location: 1632504..1634156
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0E15_RS08250 comGC 1632504..1632815 (-) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  E0E15_RS08260 - 1632984..1634156 (+) 1173 WP_000195429.1 IS256-like element IS256 family transposase -

Sequence


Protein


Download         Length: 103 a.a.        Molecular weight: 11315.36 Da        Isoelectric Point: 8.5268

>NTDB_id=1115832 E0E15_RS08250 WP_000472256.1 1632504..1632815(-) (comGC) [Staphylococcus aureus strain BPH2019 isolate BPH2019]
MFKFLKKTQAFTLIEMLLVLLIISLLLILIIPNIAKQTAHIQSTGCNAQVKMVNSQIEAYALKHNRNPSSIEDLIADGFI
KEAQKTCKSGETITISNGEAVAN

Nucleotide


Download         Length: 312 bp        

>NTDB_id=1115832 E0E15_RS08250 WP_000472256.1 1632504..1632815(-) (comGC) [Staphylococcus aureus strain BPH2019 isolate BPH2019]
ATGTTTAAATTTCTTAAGAAAACTCAAGCGTTTACATTGATAGAGATGCTATTAGTGTTATTAATCATCAGTTTATTATT
AATTTTAATCATTCCAAATATTGCTAAACAAACTGCTCACATACAATCAACAGGTTGTAATGCACAGGTAAAAATGGTTA
ATAGTCAAATTGAAGCGTATGCATTGAAACATAATAGAAATCCATCGTCTATTGAAGACTTAATTGCAGATGGTTTTATA
AAAGAAGCACAAAAGACATGTAAATCAGGAGAGACAATCACAATTAGTAATGGAGAAGCAGTTGCAAATTAG


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC Staphylococcus aureus MW2

100

100

1

  comGC Staphylococcus aureus N315

100

100

1

  comGC/cglC Streptococcus pneumoniae TIGR4

46.078

99.029

0.456

  comGC/cglC Streptococcus pneumoniae Rx1

46.078

99.029

0.456

  comGC/cglC Streptococcus pneumoniae D39

46.078

99.029

0.456

  comGC/cglC Streptococcus pneumoniae R6

46.078

99.029

0.456

  comGC/cglC Streptococcus mitis SK321

51.163

83.495

0.427

  comGC/cglC Streptococcus mitis NCTC 12261

51.163

83.495

0.427

  comYC Streptococcus gordonii str. Challis substr. CH1

42.857

95.146

0.408

  comYC Streptococcus suis isolate S10

50

75.728

0.379

  comGC Bacillus subtilis subsp. subtilis str. 168

41.758

88.35

0.369

  comGC Lactococcus lactis subsp. cremoris KW2

46.341

79.612

0.369


Multiple sequence alignment