Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   AT689_RS04290 Genome accession   NZ_LN831051
Coordinates   804272..805528 (+) Length   418 a.a.
NCBI ID   WP_000642707.1    Uniprot ID   A0A0B7L5W3
Organism   Streptococcus pneumoniae strain NCTC7465     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 799272..810528
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AT689_RS04255 - 799290..799586 (-) 297 Protein_804 lactococcin 972 family bacteriocin -
  AT689_RS04260 (ERS445053_00830) - 799901..800071 (-) 171 WP_000742180.1 PhrA family quorum-sensing system peptide -
  AT689_RS04265 (ERS445053_00831) - 800260..801123 (+) 864 WP_000105296.1 helix-turn-helix domain-containing protein -
  AT689_RS04270 (ERS445053_00832) comM 801506..802126 (+) 621 WP_000839908.1 hypothetical protein Regulator
  AT689_RS04275 (ERS445053_00833) tsaE 802212..802655 (+) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  AT689_RS04280 (ERS445053_00834) - 802645..803163 (+) 519 WP_000455536.1 GNAT family N-acetyltransferase -
  AT689_RS04285 (ERS445053_00835) - 803171..804187 (+) 1017 WP_000239278.1 biofilm formation/cell division transcriptional regulator BrpA -
  AT689_RS04290 (ERS445053_00836) cinA 804272..805528 (+) 1257 WP_000642707.1 competence/damage-inducible protein A Machinery gene
  AT689_RS04295 (ERS445053_00837) recA 805583..806749 (+) 1167 WP_001085462.1 recombinase RecA Machinery gene
  AT689_RS04300 (ERS445053_00838) - 807056..808426 (+) 1371 WP_001036295.1 MATE family efflux transporter -
  AT689_RS04305 (ERS445053_00839) lytA 808802..809758 (+) 957 WP_000405234.1 N-acetylmuramoyl-L-alanine amidase LytA -
  AT689_RS04310 - 810117..810278 (+) 162 WP_000289348.1 helix-turn-helix domain-containing protein -
  AT689_RS04315 (ERS445053_00840) - 810265..810471 (+) 207 WP_000366085.1 hypothetical protein -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45061.46 Da        Isoelectric Point: 4.6027

>NTDB_id=1114378 AT689_RS04290 WP_000642707.1 804272..805528(+) (cinA) [Streptococcus pneumoniae strain NCTC7465]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQT
LAKFLGKALVFDPQAQEKLDIFFALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLRLSTKASSQEEANQALDILENQI
LDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQGKTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRML
DIPAKNLEEHGVVSEFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIGGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=1114378 AT689_RS04290 WP_000642707.1 804272..805528(+) (cinA) [Streptococcus pneumoniae strain NCTC7465]
ATGAAAGCAGAAATCATTGCTGTTGGAACAGAGATTTTGACAGGACAGATTGTCAACACCAATGCCCAGTTTTTGTCGGA
AAAACTAGCTGAGATTGGGGTAGATGTATATTTTCAGACGGCTGTAGGAGACAATGAAGTTCGTCTCTTGTCTTTGCTTG
AGATTGCCAGTCAACGTAGCAGTCTGGTGATTTTGACAGGCGGTTTGGGGCCAACTGAGGACGACCTAACCAAACAAACC
CTAGCTAAATTTTTAGGGAAAGCATTAGTCTTTGATCCTCAGGCTCAGGAGAAGTTGGATATCTTTTTTGCCCTGCGACC
AGACTATGCCCGAACACCGAATAACGAAAGACAAGCTCAAATTGTAGAAGGAGCGATTCCACTGCCAAACGAAACAGGAC
TGGCTGTTGGAGGAAAATTAGAAGTAGACGGAGTGACCTATGTCGTCCTTCCAGGTCCGCCAAGTGAATTGAAACCCATG
GTCTTAAACCAACTTCTACCCAAGTTGATGACAGGGAGCAAGCTGTATTCCCGAGTTCTTCGTTTCTTTGGGATTGGCGA
GAGCCAGCTGGTTACGATTTTGGCTGATTTAATTGATAATCAGATCGATCCTACCTTGGCCCCTTATGCCAAGACAGGAG
AAGTCACTCTACGTCTGTCAACAAAGGCTAGCAGTCAAGAAGAGGCGAATCAAGCGCTGGATATCTTGGAAAATCAAATC
TTGGACTGCCAGACTTTCGAAGGAATTTCTTTACGAGACTTTTGCTATGGTTATGGGGAAGAAACTAGTTTAGCCAGCAT
TGTGGTAGAAGAACTGAAAAGGCAAGGGAAAACCATCGCGGCTGCAGAGAGTTTGACGGCAGGTCTTTTCCAAGCTACCG
TGGCGAATTTTTCTGGAGTTTCAAGTATATTTAAGGGTGGTTTTGTGACCTATAGCTTGGAGGAAAAATCAAGGATGTTG
GATATTCCTGCCAAGAATTTGGAAGAACATGGTGTGGTGTCTGAATTTACAGCTCAGAAGATGGCTGAGCAGGCACGAAG
CAAGACCCAGTCTGATTTTGGAATTAGTTTGACTGGAGTGGCAGGACCAGATAGCCTAGAAGGACACCCAGTTGGGACAG
TCTTCATAGGCTTGGCGCAAGATCAAGGAACTGAGGTTATCAAGGTTAATATTGGAGGCAGAAGCCGAGCAGATGTACGT
CACATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(262-414)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7L5W3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus pneumoniae TIGR4

99.761

100

0.998
  cinA Streptococcus pneumoniae Rx1

99.522

100

0.995
  cinA Streptococcus pneumoniae R6

99.522

100

0.995
  cinA Streptococcus pneumoniae D39

99.282

100

0.993
  cinA Streptococcus mitis SK321

93.78

100

0.938
  cinA Streptococcus mitis NCTC 12261

93.541

100

0.935
  cinA Streptococcus mutans UA159

71.053

100

0.711
  cinA Streptococcus suis isolate S10

55.048

99.522

0.548
  cinA Bacillus subtilis subsp. subtilis str. 168

45.455

100

0.455

Multiple sequence alignment