Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   AT689_RS04270 Genome accession   NZ_LN831051
Coordinates   801506..802126 (+) Length   206 a.a.
NCBI ID   WP_000839908.1    Uniprot ID   A0A0B7M636
Organism   Streptococcus pneumoniae strain NCTC7465     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 796506..807126
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AT689_RS04245 (ERS445053_00826) - 796538..797170 (-) 633 WP_000571420.1 ABC transporter ATP-binding protein -
  AT689_RS04250 (ERS445053_00827) - 797172..799187 (-) 2016 WP_000732390.1 DUF1430 domain-containing protein -
  AT689_RS04255 - 799290..799586 (-) 297 Protein_804 lactococcin 972 family bacteriocin -
  AT689_RS04260 (ERS445053_00830) - 799901..800071 (-) 171 WP_000742180.1 PhrA family quorum-sensing system peptide -
  AT689_RS04265 (ERS445053_00831) - 800260..801123 (+) 864 WP_000105296.1 helix-turn-helix domain-containing protein -
  AT689_RS04270 (ERS445053_00832) comM 801506..802126 (+) 621 WP_000839908.1 hypothetical protein Regulator
  AT689_RS04275 (ERS445053_00833) tsaE 802212..802655 (+) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  AT689_RS04280 (ERS445053_00834) - 802645..803163 (+) 519 WP_000455536.1 GNAT family N-acetyltransferase -
  AT689_RS04285 (ERS445053_00835) - 803171..804187 (+) 1017 WP_000239278.1 biofilm formation/cell division transcriptional regulator BrpA -
  AT689_RS04290 (ERS445053_00836) cinA 804272..805528 (+) 1257 WP_000642707.1 competence/damage-inducible protein A Machinery gene
  AT689_RS04295 (ERS445053_00837) recA 805583..806749 (+) 1167 WP_001085462.1 recombinase RecA Machinery gene

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23552.72 Da        Isoelectric Point: 10.1254

>NTDB_id=1114377 AT689_RS04270 WP_000839908.1 801506..802126(+) (comM) [Streptococcus pneumoniae strain NCTC7465]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=1114377 AT689_RS04270 WP_000839908.1 801506..802126(+) (comM) [Streptococcus pneumoniae strain NCTC7465]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCTTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATATTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7M636

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

100

100

1
  comM Streptococcus pneumoniae R6

100

100

1
  comM Streptococcus pneumoniae TIGR4

100

100

1
  comM Streptococcus mitis NCTC 12261

38.974

94.66

0.369
  comM Streptococcus mitis SK321

38.974

94.66

0.369

Multiple sequence alignment