Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   HALO_RS12875 Genome accession   NZ_LN813019
Coordinates   2785875..2787107 (+) Length   410 a.a.
NCBI ID   WP_035579080.1    Uniprot ID   A0A0D6E9K1
Organism   Halomonas sp. R57-5     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2780875..2792107
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HALO_RS12855 (HALO2584) - 2781923..2782744 (-) 822 WP_050713501.1 inositol monophosphatase family protein -
  HALO_RS12860 (HALO2585) - 2782839..2783273 (-) 435 WP_035579085.1 anti-virulence regulator CigR family protein -
  HALO_RS12865 (HALO2586) - 2783406..2783900 (-) 495 WP_050713502.1 pilin -
  HALO_RS12870 (HALO2587) pilB 2784120..2785871 (+) 1752 WP_050713503.1 type IV-A pilus assembly ATPase PilB Machinery gene
  HALO_RS12875 (HALO2588) pilC 2785875..2787107 (+) 1233 WP_035579080.1 type II secretion system F family protein Machinery gene
  HALO_RS12880 (HALO2589) pilD 2787156..2788001 (+) 846 WP_035579078.1 A24 family peptidase Machinery gene
  HALO_RS12885 (HALO2590) coaE 2788086..2788688 (+) 603 WP_035579076.1 dephospho-CoA kinase -
  HALO_RS12890 (HALO2591) yacG 2788723..2788956 (+) 234 WP_022523595.1 DNA gyrase inhibitor YacG -
  HALO_RS12895 (HALO2592) - 2788968..2789855 (+) 888 WP_035579074.1 DNA replication terminus site-binding protein -
  HALO_RS12900 (HALO2593) - 2789895..2790236 (-) 342 WP_035583345.1 hypothetical protein -
  HALO_RS12905 (HALO2594) - 2790624..2791442 (+) 819 WP_231896712.1 helix-turn-helix transcriptional regulator -
  HALO_RS12910 (HALO2595) - 2791532..2791906 (-) 375 WP_035579070.1 histone-like nucleoid-structuring protein, MvaT/MvaU family -

Sequence

Protein


Download         Length: 410 a.a.        Molecular weight: 44785.67 Da        Isoelectric Point: 10.4540

>NTDB_id=1114041 HALO_RS12875 WP_035579080.1 2785875..2787107(+) (pilC) [Halomonas sp. R57-5]
MAKTARRRQTPAIKLVRWKWSGKGPRNRPLSGEMIGRSKAEVAAELTKQGIVIRRISKKGTLGGSGRINPNDVMVFARQM
ATMIRASIPLLQALQVVAESLKKPAMVALVQHMMSDVSSGSSFSDALRRHPKQFDRLFVNLVDAGEQSGALDQMLDRIAT
YKEKVESLKARVKKALWYPTAVMTIGIAVTMLLLIKVVPEFESMFQSFGAELPALTQMTVNLSELAQHYWLAALVAVVAA
GLLLTLSIQRSPNVAYRMHALLLRLPIIGDIMHKSAIARFSRTLATTFASGVPLVEGLDTAAGATGNKVYERAVIQTRQD
VATGQQLHFAMRMTNRFPPLAVQMVSIGEEAGSLDAMLNRVADYYEEEVDNKVDALTSLMEPVIIVVLGVLVGGVVVSMY
LPIFDLGSAL

Nucleotide


Download         Length: 1233 bp        

>NTDB_id=1114041 HALO_RS12875 WP_035579080.1 2785875..2787107(+) (pilC) [Halomonas sp. R57-5]
ATGGCTAAAACGGCACGTCGTCGCCAAACGCCCGCCATCAAGCTAGTACGCTGGAAATGGAGTGGTAAAGGCCCGCGGAA
TAGGCCGCTAAGCGGAGAGATGATTGGCCGCAGTAAAGCTGAAGTAGCCGCTGAGCTAACCAAGCAGGGTATTGTTATCC
GCCGGATTAGTAAAAAGGGCACCCTGGGTGGCAGCGGTCGCATTAATCCCAACGATGTCATGGTCTTTGCGCGCCAAATG
GCCACTATGATTCGCGCGAGCATTCCCTTACTGCAGGCGCTTCAGGTGGTGGCTGAGAGTCTCAAAAAGCCCGCCATGGT
CGCCCTGGTTCAGCATATGATGAGCGATGTCTCGTCGGGCTCAAGCTTCTCTGACGCCTTGCGCCGCCACCCAAAGCAGT
TTGATCGGCTGTTTGTTAACCTTGTCGACGCTGGCGAACAGTCGGGTGCGCTGGATCAGATGCTTGATCGTATTGCGACC
TATAAAGAGAAGGTTGAGTCGCTGAAGGCGCGGGTCAAGAAAGCACTTTGGTATCCCACCGCCGTTATGACGATCGGTAT
TGCAGTGACCATGCTGCTGTTAATCAAAGTGGTACCTGAATTTGAAAGTATGTTCCAAAGTTTTGGCGCTGAACTGCCTG
CATTGACCCAGATGACCGTGAATTTATCCGAGCTTGCCCAGCATTATTGGCTAGCAGCGCTCGTCGCAGTGGTTGCCGCT
GGGCTTCTGCTCACACTAAGTATTCAGCGCTCACCTAATGTCGCCTACCGGATGCACGCACTGCTGCTTCGGTTACCGAT
CATTGGCGATATCATGCATAAATCTGCCATCGCCCGTTTTTCGCGCACGTTAGCGACCACCTTTGCCTCCGGCGTACCGC
TCGTTGAAGGCTTAGACACCGCCGCGGGCGCCACAGGCAATAAAGTTTACGAGCGCGCAGTAATACAAACGCGCCAGGAC
GTAGCCACCGGGCAACAGCTACACTTCGCCATGCGGATGACCAACCGCTTCCCCCCCTTAGCGGTTCAAATGGTCAGCAT
CGGTGAAGAAGCGGGGTCGCTTGATGCCATGCTCAATCGCGTGGCTGATTATTACGAAGAAGAAGTCGACAATAAAGTCG
ATGCCCTCACCTCGCTGATGGAACCGGTTATTATTGTGGTACTTGGAGTACTCGTCGGCGGTGTGGTTGTCTCTATGTAT
TTACCCATCTTCGACTTGGGCTCTGCCCTCTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(280-402)

Type II secretion system (T2SS), protein F (T2SSF)

(76-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0D6E9K1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

50.376

97.317

0.49
  pilC Acinetobacter baylyi ADP1

50.38

96.341

0.485
  pilC Acinetobacter baumannii D1279779

50.38

96.341

0.485
  pilC Legionella pneumophila strain ERS1305867

47.619

97.317

0.463
  pilC Vibrio cholerae strain A1552

42.752

99.268

0.424
  pilC Vibrio campbellii strain DS40M4

42.157

99.512

0.42
  pilG Neisseria meningitidis 44/76-A

42.607

97.317

0.415
  pilG Neisseria gonorrhoeae MS11

42.607

97.317

0.415

Multiple sequence alignment