Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   HMPREF9425_RS00680 Genome accession   NZ_GL831112
Coordinates   132803..133903 (+) Length   366 a.a.
NCBI ID   WP_155809878.1    Uniprot ID   -
Organism   Streptococcus vestibularis ATCC 49124     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 127803..138903
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF9425_RS00670 (HMPREF9425_0138) - 131537..131899 (+) 363 WP_003095881.1 DUF1033 family protein -
  HMPREF9425_RS00675 (HMPREF9425_0139) comYA 131980..132921 (+) 942 WP_003095883.1 competence type IV pilus ATPase ComGA Machinery gene
  HMPREF9425_RS00680 (HMPREF9425_0140) comYB 132803..133903 (+) 1101 WP_155809878.1 competence type IV pilus assembly protein ComGB Machinery gene
  HMPREF9425_RS00685 (HMPREF9425_0141) comYC 133900..134226 (+) 327 WP_002885815.1 competence type IV pilus major pilin ComGC Machinery gene
  HMPREF9425_RS00690 (HMPREF9425_0142) comYD 134186..134614 (+) 429 WP_253665936.1 competence type IV pilus minor pilin ComGD Machinery gene
  HMPREF9425_RS00695 (HMPREF9425_0143) comGE 134646..134876 (+) 231 WP_003095891.1 competence type IV pilus minor pilin ComGE -
  HMPREF9425_RS00700 (HMPREF9425_0144) comYF 134863..135300 (+) 438 WP_003091908.1 competence type IV pilus minor pilin ComGF Machinery gene
  HMPREF9425_RS00705 (HMPREF9425_0145) comGG 135278..135595 (+) 318 WP_003092009.1 competence type IV pilus minor pilin ComGG -
  HMPREF9425_RS00710 (HMPREF9425_0146) comYH 135640..136596 (+) 957 WP_003091902.1 class I SAM-dependent methyltransferase Machinery gene
  HMPREF9425_RS00715 (HMPREF9425_0147) - 136653..137846 (+) 1194 WP_003095894.1 acetate kinase -
  HMPREF9425_RS00720 (HMPREF9425_0148) - 138097..138294 (+) 198 WP_002885716.1 helix-turn-helix transcriptional regulator -
  HMPREF9425_RS00725 (HMPREF9425_0149) - 138308..138751 (+) 444 WP_037621248.1 hypothetical protein -

Sequence

Protein


Download         Length: 366 a.a.        Molecular weight: 41689.79 Da        Isoelectric Point: 10.0986

>NTDB_id=1111719 HMPREF9425_RS00680 WP_155809878.1 132803..133903(+) (comYB) [Streptococcus vestibularis ATCC 49124]
MPVKISKAIRQPAGTNSWKAWLNKDISLKGISKGKKLKINQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKESSLSLM
KASLMRGDRLDQMFASVGFSDNIVTQIALADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKENWAIQLVQIFPQLFFVTLCGLLVLSLILYLWVKRQPALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGIDLLDLVSLMQEQKSKLFRELGADLEEALMLGQSFPDRIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QAFFNRLNKATTFVQPLIFIIVAVVIVMIYAAMLLPMYQNMEGMMS

Nucleotide


Download         Length: 1101 bp        

>NTDB_id=1111719 HMPREF9425_RS00680 WP_155809878.1 132803..133903(+) (comYB) [Streptococcus vestibularis ATCC 49124]
TTGCCTGTGAAAATTTCCAAAGCCATTCGTCAGCCAGCTGGAACCAACAGTTGGAAGGCTTGGTTAAACAAGGATATCTC
ACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAATCAGCAAGTCAAGGTTATCCAGCTCTTCAAACAACTTCTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGTTGAAAGAATCGTCATTATCTCTTATG
AAAGCAAGCTTAATGCGAGGCGACAGGCTAGACCAGATGTTTGCGTCAGTGGGTTTTTCGGACAACATTGTTACTCAGAT
TGCCCTTGCTGATAAGCACGGTAATCTTCTAGGGAGTTTAACCAAGATTGAAACCTACATGCTTCGCATGACCAAGGTTC
GTAAGAAACTCATGGAGGTAGCGACCTACCCTATCCTACTTCTGGGTTTCCTGATTCTGATTATGTTGGGGCTCAAAAAT
TATCTTCTTCCTCAATTGTTAGAGGGGGATGGTAAGGAGAATTGGGCTATACAGTTGGTTCAGATTTTTCCCCAGCTCTT
TTTTGTGACTTTGTGCGGACTTCTTGTATTAAGCTTAATTCTCTATCTATGGGTGAAACGCCAGCCAGCCCTTGTCTTTT
ATCGACGAATGGCAAAAATCCCTTTTATAGGCCAAACTGTCAGGCTATATACGACCGCCTATTATGCTAGGGAATGGGGA
AATCTCTTAGGACAAGGGATTGACCTGTTAGACTTGGTTTCTCTTATGCAAGAGCAAAAGTCTAAGCTCTTTCGTGAGCT
GGGGGCTGATTTAGAAGAGGCCTTGATGCTAGGACAGAGTTTTCCTGATCGTATTGCTAGTCACCCTTTTTTCACTAAGG
AACTATCCTTGATTATTGCTTATGGAGAGGCTAATGCTAGGTTGGGCTATGAGTTAGAAGTCTATGCTGAAGAGGTTTGG
CAGGCTTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTATTATTGTTGCTGTCGTGATTGT
AATGATCTATGCAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(51-164)

Type II secretion system (T2SS), protein F (T2SSF)

(236-356)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

55.102

93.716

0.516
  comYB Streptococcus mutans UA159

55.102

93.716

0.516
  comYB Streptococcus gordonii str. Challis substr. CH1

51.603

93.716

0.484
  comGB/cglB Streptococcus mitis NCTC 12261

50.737

92.623

0.47
  comGB/cglB Streptococcus mitis SK321

50

92.35

0.462
  comGB/cglB Streptococcus pneumoniae Rx1

49.704

92.35

0.459
  comGB/cglB Streptococcus pneumoniae D39

49.704

92.35

0.459
  comGB/cglB Streptococcus pneumoniae R6

49.704

92.35

0.459
  comGB/cglB Streptococcus pneumoniae TIGR4

49.704

92.35

0.459
  comGB Lactococcus lactis subsp. cremoris KW2

44.681

89.891

0.402

Multiple sequence alignment