Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   HMPREF9319_RS09535 Genome accession   NZ_GL397128
Coordinates   1984338..1985597 (-) Length   419 a.a.
NCBI ID   WP_003066899.1    Uniprot ID   A0AAW6YLT2
Organism   Streptococcus equinus ATCC 700338     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1979338..1990597
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF9319_RS11380 - 1980904..1981032 (-) 129 WP_259293846.1 hypothetical protein -
  HMPREF9319_RS09510 (HMPREF9319_1989) - 1981124..1981429 (-) 306 WP_003066884.1 DUF1292 domain-containing protein -
  HMPREF9319_RS09515 (HMPREF9319_1990) ruvX 1981462..1981881 (-) 420 WP_013852327.1 Holliday junction resolvase RuvX -
  HMPREF9319_RS09520 (HMPREF9319_1991) - 1981878..1982147 (-) 270 WP_003066890.1 IreB family regulatory phosphoprotein -
  HMPREF9319_RS09525 (HMPREF9319_1992) spx 1982466..1982864 (-) 399 WP_003066893.1 transcriptional regulator Spx -
  HMPREF9319_RS09530 (HMPREF9319_1993) recA 1983134..1984288 (-) 1155 WP_003066896.1 recombinase RecA Machinery gene
  HMPREF9319_RS09535 (HMPREF9319_1994) cinA 1984338..1985597 (-) 1260 WP_003066899.1 competence/damage-inducible protein A Machinery gene
  HMPREF9319_RS09540 (HMPREF9319_1996) - 1985967..1986920 (-) 954 WP_003066905.1 MFS transporter -
  HMPREF9319_RS11285 (HMPREF9319_1997) - 1987367..1987576 (-) 210 WP_003066908.1 hypothetical protein -
  HMPREF9319_RS11290 (HMPREF9319_1998) - 1987534..1987815 (-) 282 WP_003066911.1 hypothetical protein -
  HMPREF9319_RS11295 (HMPREF9319_1999) - 1987885..1988055 (-) 171 WP_231729898.1 hypothetical protein -
  HMPREF9319_RS11300 (HMPREF9319_2000) - 1988116..1988292 (-) 177 WP_003066916.1 hypothetical protein -
  HMPREF9319_RS09555 (HMPREF9319_2001) - 1988440..1989291 (+) 852 WP_003066919.1 helix-turn-helix domain-containing protein -
  HMPREF9319_RS09560 (HMPREF9319_2002) ruvA 1989371..1989964 (-) 594 WP_003066922.1 Holliday junction branch migration protein RuvA -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45423.82 Da        Isoelectric Point: 5.1768

>NTDB_id=1111711 HMPREF9319_RS09535 WP_003066899.1 1984338..1985597(-) (cinA) [Streptococcus equinus ATCC 700338]
MKAEIIAVGTEILTGQITNTNAQFLSEEFAKLGIDVFFQTAVGDNEERLLSVIDLASKRSELVVLCGGLGPTEDDLTKQT
LAKYLGRDLVFDEQANKRLDEFFATRPQFARTANNERQAQLIEGSIPLQNSTGLAVGGVLEVNGVTYVVLPGPPSELKPM
VLDSLVPLLSGDHKQLYSRVLRFFGIGESQLVTVLADLIDNQTDPTIAPYAKTGEVTLRLSTKADDVTSAKAKLDALEHK
ILAKKTLNSIPLEQLLYGYGDDNNMARVVFDLLKEKHKTITAAESLTAGLFQSSIADFSGSSAVFNGGFVTYSIEEKSKM
LHIPLKDLQEHGVVSHFTAEKMAEQSRLLTDADFGIGLTGVAGPDSLEGHPAGTVFIGIATREKVHSIRVVIGGRSRSDV
RYIATLYAFNLVRQALLQG

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=1111711 HMPREF9319_RS09535 WP_003066899.1 1984338..1985597(-) (cinA) [Streptococcus equinus ATCC 700338]
ATGAAAGCTGAAATCATTGCTGTGGGAACAGAAATTCTAACAGGACAAATCACAAATACAAATGCTCAATTTTTATCGGA
AGAATTTGCCAAGTTAGGAATTGATGTGTTCTTTCAAACAGCTGTTGGTGATAATGAAGAACGTCTTTTATCAGTTATTG
ATTTAGCAAGCAAGCGAAGTGAATTAGTTGTCTTATGTGGAGGGCTTGGTCCGACAGAAGACGATTTAACAAAACAAACG
TTAGCAAAATATTTGGGACGCGATTTAGTCTTTGATGAACAAGCTAACAAGCGTTTGGACGAATTTTTTGCGACACGTCC
GCAGTTTGCTAGAACGGCTAATAACGAACGTCAAGCACAGCTGATTGAAGGGTCAATACCGTTGCAAAATAGCACTGGTT
TGGCTGTTGGTGGCGTGCTAGAAGTAAATGGCGTGACCTACGTTGTTCTCCCTGGACCACCGAGTGAATTAAAACCAATG
GTATTGGATTCTCTAGTGCCTTTGTTGTCTGGAGACCATAAGCAGCTTTATTCACGTGTGTTGCGTTTCTTTGGGATTGG
TGAAAGCCAGTTAGTGACCGTCTTGGCAGATTTGATTGATAACCAAACAGACCCAACGATTGCTCCGTATGCGAAAACAG
GTGAGGTGACCCTTCGTTTATCAACCAAGGCAGATGATGTGACGTCAGCAAAAGCGAAATTGGATGCTCTAGAGCATAAA
ATTCTAGCCAAAAAAACATTAAATAGTATTCCTCTTGAACAGTTACTTTATGGCTACGGTGATGATAACAATATGGCGCG
TGTTGTTTTTGATTTGTTGAAAGAAAAGCACAAAACTATTACAGCTGCAGAAAGTTTGACCGCAGGGCTATTCCAATCTA
GTATCGCTGATTTTTCAGGGTCATCTGCAGTATTTAATGGCGGATTTGTGACGTATAGTATAGAAGAAAAATCAAAAATG
CTTCACATTCCTCTTAAAGATTTGCAAGAACATGGTGTAGTAAGTCACTTTACAGCTGAAAAAATGGCAGAGCAATCACG
TTTATTGACAGATGCTGATTTTGGTATCGGTTTGACAGGTGTTGCAGGACCAGATAGCTTAGAAGGACATCCAGCAGGAA
CAGTTTTCATTGGTATTGCGACTAGAGAAAAAGTTCATTCTATTCGTGTTGTTATAGGTGGGCGAAGCCGTTCAGACGTC
CGTTATATTGCTACTTTATATGCTTTCAACTTAGTACGTCAAGCTTTATTACAAGGCTAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)

Competence-damaged protein (CinA)

(264-415)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

72.182

99.523

0.718
  cinA Streptococcus mitis SK321

71.292

99.761

0.711
  cinA Streptococcus mitis NCTC 12261

71.053

99.761

0.709
  cinA Streptococcus pneumoniae Rx1

70.335

99.761

0.702
  cinA Streptococcus pneumoniae TIGR4

70.335

99.761

0.702
  cinA Streptococcus pneumoniae R6

70.335

99.761

0.702
  cinA Streptococcus pneumoniae D39

70.096

99.761

0.699
  cinA Streptococcus suis isolate S10

53.846

99.284

0.535
  cinA Bacillus subtilis subsp. subtilis str. 168

45.498

100

0.458

Multiple sequence alignment