Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   ID09_RS06580 Genome accession   NZ_CP008921
Coordinates   1353497..1354159 (-) Length   220 a.a.
NCBI ID   WP_011922190.1    Uniprot ID   A0A0H3MVS9
Organism   Streptococcus suis 6407     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1348497..1359159
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ID09_RS06560 (ID09_06745) - 1349375..1350202 (-) 828 WP_024381560.1 hypothetical protein -
  ID09_RS06565 (ID09_06750) - 1350296..1350952 (-) 657 WP_023370708.1 CBS domain-containing protein -
  ID09_RS06575 (ID09_06760) comEC/celB 1351276..1353513 (-) 2238 WP_024381561.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ID09_RS06580 (ID09_06765) comEA/celA/cilE 1353497..1354159 (-) 663 WP_011922190.1 helix-hairpin-helix domain-containing protein Machinery gene
  ID09_RS06585 (ID09_06770) - 1354222..1354971 (-) 750 WP_012775039.1 lysophospholipid acyltransferase family protein -
  ID09_RS06590 (ID09_06775) - 1355118..1356563 (+) 1446 WP_024381562.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  ID09_RS06595 (ID09_06780) - 1356715..1357515 (+) 801 WP_024381563.1 ABC transporter ATP-binding protein -
  ID09_RS06600 (ID09_06785) - 1357512..1358441 (+) 930 WP_024381564.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23410.01 Da        Isoelectric Point: 4.0676

>NTDB_id=110873 ID09_RS06580 WP_011922190.1 1353497..1354159(-) (comEA/celA/cilE) [Streptococcus suis 6407]
MDTIKTYIEMLKEYKWQIALPAVAGLLMATFLIFSQPAKSDQTGLTDFPQTEQASSSQEQTEETSTEESEELSQLTVDVK
GAVEKPGLYTLEAGARVNDAVEAAGGLTSQADPKSINLAQKLSDEAVVYVASKDENISVVASTTASSAMSPEEKSTSLVN
LNTATEADLQTISGIGAKRAADIIAYREANGGFKSVNDLNNVSGIGDKTMESIRPYVTVE

Nucleotide


Download         Length: 663 bp        

>NTDB_id=110873 ID09_RS06580 WP_011922190.1 1353497..1354159(-) (comEA/celA/cilE) [Streptococcus suis 6407]
ATGGATACGATTAAAACTTATATAGAAATGCTTAAAGAATACAAGTGGCAAATTGCTCTGCCAGCAGTGGCTGGCTTGCT
AATGGCGACGTTTTTAATATTCAGCCAACCTGCTAAGTCTGATCAAACAGGACTGACAGATTTTCCTCAAACCGAGCAAG
CTTCTAGCAGTCAGGAGCAGACGGAGGAAACCAGTACAGAAGAGAGTGAGGAGCTCAGCCAGCTAACCGTTGATGTCAAA
GGAGCGGTGGAAAAGCCTGGGTTATATACTTTAGAAGCTGGTGCGCGTGTCAATGACGCAGTTGAAGCAGCTGGCGGCTT
GACCAGTCAGGCAGACCCCAAGTCTATCAATCTGGCTCAGAAGCTCAGCGATGAGGCGGTGGTCTATGTAGCCAGCAAGG
ACGAAAACATCTCGGTGGTGGCCAGCACGACTGCCAGCTCTGCTATGTCTCCAGAAGAAAAAAGCACCAGTCTGGTCAAT
CTGAATACGGCGACTGAGGCGGACTTGCAGACCATTTCGGGTATCGGTGCCAAGCGGGCGGCGGACATTATCGCCTATCG
TGAGGCAAACGGTGGCTTCAAGTCGGTGAACGACCTCAACAATGTTTCGGGCATTGGCGACAAGACCATGGAAAGCATTC
GGCCTTATGTCACGGTTGAGTAA

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(157-218)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MVS9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

47.945

99.545

0.477
  comEA/celA/cilE Streptococcus pneumoniae Rx1

47.945

99.545

0.477
  comEA/celA/cilE Streptococcus pneumoniae D39

47.945

99.545

0.477
  comEA/celA/cilE Streptococcus pneumoniae R6

47.945

99.545

0.477
  comEA/celA/cilE Streptococcus mitis NCTC 12261

47.945

99.545

0.477
  comEA/celA/cilE Streptococcus mitis SK321

46.637

100

0.473
  comEA Streptococcus thermophilus LMD-9

59.259

73.636

0.436
  comEA Lactococcus lactis subsp. cremoris KW2

37.788

98.636

0.373
  comEA Bacillus subtilis subsp. subtilis str. 168

37.559

96.818

0.364

Multiple sequence alignment