Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ACK8QM_RS04250 Genome accession   NZ_CP180558
Coordinates   888329..889570 (+) Length   413 a.a.
NCBI ID   WP_014569352.1    Uniprot ID   -
Organism   Lacticaseibacillus rhamnosus strain MRD-YKTA     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 880413..929160 888329..889570 within 0


Gene organization within MGE regions


Location: 880413..929160
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACK8QM_RS04220 - 880911..883211 (+) 2301 WP_014569347.1 DNA translocase FtsK -
  ACK8QM_RS04225 yfmF 883220..884482 (+) 1263 WP_014569348.1 EF-P 5-aminopentanol modification-associated protein YfmF -
  ACK8QM_RS04230 yfmH 884479..885771 (+) 1293 WP_014569349.1 EF-P 5-aminopentanol modification-associated protein YfmH -
  ACK8QM_RS04235 ymfI 885771..886499 (+) 729 WP_014569350.1 elongation factor P 5-aminopentanone reductase -
  ACK8QM_RS04240 - 886586..887521 (+) 936 WP_005688668.1 helix-turn-helix domain-containing protein -
  ACK8QM_RS04245 pgsA 887518..888108 (+) 591 WP_014569351.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  ACK8QM_RS04250 cinA 888329..889570 (+) 1242 WP_014569352.1 competence/damage-inducible protein A Machinery gene
  ACK8QM_RS04255 recA 889622..890674 (+) 1053 WP_005688187.1 recombinase RecA Machinery gene
  ACK8QM_RS04260 rny 891299..892870 (+) 1572 WP_005684479.1 ribonuclease Y -
  ACK8QM_RS04265 - 892959..893615 (-) 657 WP_029943817.1 YigZ family protein -
  ACK8QM_RS04270 - 893643..894908 (+) 1266 WP_014569356.1 DEAD/DEAH box helicase -
  ACK8QM_RS04275 - 895067..895585 (+) 519 WP_005688681.1 ComF family protein -
  ACK8QM_RS04280 hpf 895777..896334 (+) 558 WP_005684485.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  ACK8QM_RS04285 secA 896917..899280 (+) 2364 WP_005684487.1 preprotein translocase subunit SecA -
  ACK8QM_RS04290 prfB 899422..900538 (+) 1117 WP_154241369.1 peptide chain release factor 2 -
  ACK8QM_RS04295 ftsE 900615..901301 (+) 687 WP_005684489.1 cell division ATP-binding protein FtsE -
  ACK8QM_RS04300 ftsX 901291..902178 (+) 888 WP_005684490.1 permease-like cell division protein FtsX -
  ACK8QM_RS04305 - 902256..902393 (+) 138 WP_014569359.1 hypothetical protein -
  ACK8QM_RS04310 - 902449..903546 (+) 1098 WP_014569360.1 PDZ domain-containing protein -
  ACK8QM_RS04315 - 903543..904247 (+) 705 WP_005688690.1 response regulator transcription factor -
  ACK8QM_RS04320 pnpS 904240..905907 (+) 1668 WP_014569361.1 two-component system histidine kinase PnpS -
  ACK8QM_RS04325 - 905997..906863 (+) 867 WP_005684496.1 phosphate ABC transporter substrate-binding protein PstS family protein -
  ACK8QM_RS04330 pstC 907011..907934 (+) 924 WP_005684497.1 phosphate ABC transporter permease subunit PstC -
  ACK8QM_RS04335 pstA 907931..908815 (+) 885 WP_005684499.1 phosphate ABC transporter permease PstA -
  ACK8QM_RS04340 pstB 908886..909704 (+) 819 WP_005713669.1 phosphate ABC transporter ATP-binding protein PstB -
  ACK8QM_RS04345 pstB 909714..910478 (+) 765 WP_005684501.1 phosphate ABC transporter ATP-binding protein PstB -
  ACK8QM_RS04350 phoU 910489..911166 (+) 678 WP_005684502.1 phosphate signaling complex protein PhoU -
  ACK8QM_RS04355 - 911420..912298 (-) 879 WP_048653158.1 IS3 family transposase -
  ACK8QM_RS04360 - 912295..913023 (-) 729 WP_014569363.1 helix-turn-helix domain-containing protein -
  ACK8QM_RS04365 liaX 913592..914942 (+) 1351 Protein_831 daptomycin-sensing surface protein LiaX -
  ACK8QM_RS04370 - 914954..915214 (+) 261 WP_005688700.1 hypothetical protein -
  ACK8QM_RS04375 - 915217..915552 (+) 336 WP_005684507.1 phage holin family protein -
  ACK8QM_RS04380 hprK 915819..916778 (+) 960 WP_005684508.1 HPr(Ser) kinase/phosphatase -
  ACK8QM_RS04385 lgt 916780..917607 (+) 828 WP_014569365.1 prolipoprotein diacylglyceryl transferase -
  ACK8QM_RS04390 - 917618..918673 (+) 1056 WP_014569366.1 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase -
  ACK8QM_RS04395 trxB 918739..919686 (+) 948 WP_005684511.1 thioredoxin-disulfide reductase -
  ACK8QM_RS04400 - 919938..921665 (+) 1728 WP_014569367.1 phospho-sugar mutase -
  ACK8QM_RS04405 - 922125..922772 (+) 648 WP_014569368.1 YfbR-like 5'-deoxynucleotidase -
  ACK8QM_RS04410 uvrB 923043..925058 (+) 2016 WP_005688715.1 excinuclease ABC subunit UvrB -
  ACK8QM_RS04415 uvrA 925239..928133 (+) 2895 WP_014569369.1 excinuclease ABC subunit UvrA -
  ACK8QM_RS04420 - 928335..928874 (+) 540 WP_014569370.1 HdeD family acid-resistance protein -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 44472.12 Da        Isoelectric Point: 7.2504

>NTDB_id=1096581 ACK8QM_RS04250 WP_014569352.1 888329..889570(+) (cinA) [Lacticaseibacillus rhamnosus strain MRD-YKTA]
MQAEIIAIGTEILMGQITNTNGAYMAKQLATLGIASYHQQVVGDNAKRLADAISLAEQRSDIVILIGGLGPTPDDLTKQT
LAAHLNLPLVEDADAMAKLAARVKQQQRPMTPNNRLQAMYPQGAIVLANRVGLAVGAWVEQRQHAYVLLPGPPKEFVPMV
DHELLPRLAKYSGHQEVLESRVMRFFGIGESQLVTDLSDLIANQTNPTLATYIKDHEVTVRVTASGKTQAEAAAKLEPMI
GIIMDREGRYFYGYGDDNSLAQELVKALAASDKQISAAESLTAGAFQAALGDVPGVSAYFKGGFVTYALATKAAFLNIDA
RQLSEHGVVSEFTAKAMAEHARQRAAADIAVSFTGVAGPDKLEGQPAGTVWIGLARLGEKPIAQVYHFPGGRNDVRKRAV
MTGMMMVLKRLRE

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=1096581 ACK8QM_RS04250 WP_014569352.1 888329..889570(+) (cinA) [Lacticaseibacillus rhamnosus strain MRD-YKTA]
ATGCAAGCAGAAATTATTGCTATCGGAACGGAAATTCTGATGGGACAAATTACAAATACAAATGGCGCGTATATGGCTAA
ACAACTGGCTACATTAGGTATTGCGAGCTATCATCAACAGGTTGTTGGGGATAATGCAAAACGACTGGCTGACGCGATAA
GTTTGGCGGAACAACGCAGTGATATCGTTATTTTGATTGGTGGTTTAGGACCAACACCGGATGATTTAACGAAGCAAACC
CTAGCCGCACACCTGAATTTACCCTTGGTGGAAGACGCTGACGCTATGGCCAAGTTGGCTGCGCGGGTTAAACAACAGCA
ACGTCCAATGACACCCAATAATCGCCTGCAAGCGATGTATCCCCAAGGCGCAATCGTATTGGCCAATCGTGTCGGGTTGG
CGGTCGGCGCATGGGTTGAGCAGCGCCAACACGCCTATGTTTTATTGCCGGGACCACCTAAAGAGTTTGTGCCGATGGTT
GATCATGAACTGTTGCCACGACTGGCAAAATATAGCGGGCATCAAGAAGTTTTGGAAAGTCGCGTGATGCGTTTCTTTGG
TATCGGCGAATCGCAACTTGTGACAGACTTAAGTGATTTAATTGCCAACCAGACGAATCCGACACTTGCAACTTATATAA
AAGATCATGAGGTGACAGTTCGGGTAACTGCGAGTGGCAAAACACAAGCAGAAGCCGCGGCGAAACTTGAGCCAATGATC
GGCATCATTATGGATCGTGAAGGTCGCTACTTTTACGGCTACGGTGACGATAACAGTCTTGCCCAGGAATTAGTCAAAGC
ATTGGCGGCTAGTGATAAGCAAATTAGTGCCGCTGAAAGTCTGACTGCAGGTGCATTTCAAGCGGCATTGGGAGACGTTC
CGGGAGTCTCGGCTTATTTCAAAGGCGGCTTCGTTACGTACGCTTTAGCGACAAAAGCTGCATTTTTAAATATTGATGCC
CGTCAGCTATCAGAACATGGTGTGGTGAGTGAATTTACTGCCAAAGCAATGGCAGAGCATGCTCGTCAACGAGCGGCGGC
AGACATTGCCGTTAGTTTTACCGGAGTTGCCGGTCCTGACAAGCTGGAAGGACAGCCAGCCGGCACCGTCTGGATTGGTT
TGGCGCGGTTAGGAGAGAAACCAATAGCACAAGTTTATCATTTTCCGGGTGGGCGAAATGACGTCCGCAAGCGCGCCGTT
ATGACGGGGATGATGATGGTGTTGAAGCGTTTACGCGAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(258-410)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

52.019

100

0.53
  cinA Streptococcus mitis NCTC 12261

52.019

100

0.53
  cinA Streptococcus pneumoniae TIGR4

51.544

100

0.525
  cinA Streptococcus pneumoniae R6

51.069

100

0.521
  cinA Streptococcus pneumoniae Rx1

51.069

100

0.521
  cinA Streptococcus mutans UA159

51.442

100

0.518
  cinA Streptococcus pneumoniae D39

50.831

100

0.518
  cinA Bacillus subtilis subsp. subtilis str. 168

44.66

99.758

0.446
  cinA Streptococcus suis isolate S10

42.593

91.525

0.39

Multiple sequence alignment