Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   ACK8DD_RS16835 Genome accession   NZ_CP179880
Coordinates   3574219..3575445 (+) Length   408 a.a.
NCBI ID   WP_000279216.1    Uniprot ID   A0A009IRK3
Organism   Acinetobacter baumannii strain MRSN548254     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 3569219..3580445
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACK8DD_RS16800 (ACK8DD_16800) rimP 3569884..3570408 (-) 525 WP_000777730.1 ribosome maturation factor RimP -
  ACK8DD_RS16820 (ACK8DD_16820) secG 3571050..3571379 (-) 330 WP_000555570.1 preprotein translocase subunit SecG -
  ACK8DD_RS16825 (ACK8DD_16825) tpiA 3571392..3572186 (-) 795 WP_000016932.1 triose-phosphate isomerase -
  ACK8DD_RS16830 (ACK8DD_16830) pilB 3572477..3574189 (+) 1713 WP_001274987.1 type IV-A pilus assembly ATPase PilB Machinery gene
  ACK8DD_RS16835 (ACK8DD_16835) pilC 3574219..3575445 (+) 1227 WP_000279216.1 type II secretion system F family protein Machinery gene
  ACK8DD_RS16840 (ACK8DD_16840) pilD 3575445..3576305 (+) 861 WP_004748468.1 prepilin peptidase Machinery gene
  ACK8DD_RS16845 (ACK8DD_16845) coaE 3576307..3576903 (+) 597 WP_000874125.1 dephospho-CoA kinase -
  ACK8DD_RS16850 (ACK8DD_16850) - 3576900..3577814 (-) 915 WP_000075015.1 DMT family transporter -
  ACK8DD_RS16855 (ACK8DD_16855) rlmB 3577850..3578599 (-) 750 WP_001118149.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  ACK8DD_RS16860 (ACK8DD_16860) - 3578701..3579027 (-) 327 WP_000099685.1 pyrimidine/purine nucleoside phosphorylase -
  ACK8DD_RS16865 (ACK8DD_16865) - 3579104..3580414 (-) 1311 WP_004748473.1 tetratricopeptide repeat protein -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44936.43 Da        Isoelectric Point: 9.9566

>NTDB_id=1093366 ACK8DD_RS16835 WP_000279216.1 3574219..3575445(+) (pilC) [Acinetobacter baumannii strain MRSN548254]
MAVKKAQMMPTFAYEGVDRKGVKIKGELPAKNMALAKVTLRKQGVTVRNIREKRKNILEGLFKKKVTTLDITIFTRQLAT
MMKAGVPLVQGFEIVAEGLENPAMREVVLGIKGEVEGGSTFASALRKYPQHFDNLFCSLVESGEQSGALETMLDRVAIYK
EKSELLKQKIKKAMKYPATVIVVAIVVTIILMVKVVPVFQDLFASFGADLPAFTQMVVNMSKWMQEYWFIMIIAIGAVIA
AFLEAKKRSKKFRDGLDKLALKLPIFGDLVYKAIIARYSRTLATTFAAGVPLIDALESTAGATNNVIYEKAVMKIREDVA
TGQQLQFAMRVSNRFPSMAIQMVAIGEESGALDSMLDKVATYYENEVDNAVDGLTSMMEPLIMAILGVLVGGLVIAMYLP
IFQMGSVV

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=1093366 ACK8DD_RS16835 WP_000279216.1 3574219..3575445(+) (pilC) [Acinetobacter baumannii strain MRSN548254]
ATGGCTGTCAAAAAAGCACAAATGATGCCGACTTTTGCTTATGAAGGGGTTGACCGTAAGGGCGTAAAAATCAAAGGAGA
ACTTCCGGCTAAAAACATGGCTTTAGCCAAAGTGACCTTACGCAAACAAGGGGTGACTGTTCGAAATATACGTGAAAAAC
GTAAAAATATTCTTGAAGGTTTATTCAAGAAAAAAGTCACCACACTCGATATTACGATTTTTACTCGACAACTGGCGACC
ATGATGAAAGCTGGTGTACCACTCGTACAAGGCTTTGAAATTGTAGCTGAAGGTTTAGAAAACCCGGCCATGCGTGAGGT
TGTACTCGGTATTAAAGGTGAAGTCGAAGGTGGTAGTACTTTTGCCTCAGCTTTAAGAAAATATCCTCAACATTTTGATA
ACTTGTTTTGTTCACTTGTTGAATCTGGTGAACAATCAGGCGCACTCGAAACGATGCTGGACCGCGTTGCAATTTACAAA
GAAAAAAGTGAATTGCTCAAGCAAAAAATCAAGAAAGCAATGAAATACCCGGCAACAGTTATTGTAGTAGCCATTGTGGT
GACCATTATTTTGATGGTTAAAGTAGTTCCCGTTTTCCAAGATTTATTTGCGTCTTTTGGAGCAGATTTACCTGCATTTA
CGCAAATGGTTGTGAATATGTCGAAATGGATGCAGGAATACTGGTTCATTATGATTATTGCGATTGGCGCAGTCATTGCT
GCCTTTCTGGAAGCAAAAAAACGCAGTAAAAAGTTTCGTGACGGCTTAGATAAACTGGCGCTTAAGTTGCCTATTTTTGG
GGACTTGGTTTATAAGGCAATCATTGCCCGCTATAGCCGCACGCTTGCTACAACATTTGCCGCAGGTGTTCCGCTTATTG
ATGCATTAGAATCGACTGCTGGCGCAACCAATAACGTGATTTATGAAAAAGCTGTGATGAAAATTCGTGAAGATGTCGCA
ACAGGTCAACAGCTTCAGTTTGCTATGCGGGTCTCTAACCGTTTTCCATCGATGGCTATACAAATGGTTGCAATTGGTGA
AGAATCGGGTGCACTAGACAGCATGCTCGATAAAGTTGCCACTTATTATGAAAATGAAGTGGATAATGCCGTTGATGGTT
TAACCTCTATGATGGAACCTTTAATTATGGCAATTTTAGGGGTGCTCGTAGGCGGTCTGGTCATTGCTATGTATCTTCCA
ATTTTCCAAATGGGCTCAGTTGTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(279-400)

Type II secretion system (T2SS), protein F (T2SSF)

(74-197)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A009IRK3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Acinetobacter baumannii D1279779

99.755

100

0.998
  pilC Acinetobacter baylyi ADP1

86.029

100

0.86
  pilC Pseudomonas stutzeri DSM 10701

59.753

99.265

0.593
  pilC Legionella pneumophila strain ERS1305867

53.827

99.265

0.534
  pilG Neisseria gonorrhoeae MS11

47.236

97.549

0.461
  pilG Neisseria meningitidis 44/76-A

47.236

97.549

0.461
  pilC Vibrio cholerae strain A1552

42.647

100

0.426
  pilC Vibrio campbellii strain DS40M4

41.089

99.02

0.407
  pilC Thermus thermophilus HB27

36.658

98.284

0.36

Multiple sequence alignment