Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ACJWMD_RS00360 Genome accession   NZ_CP177182
Coordinates   58088..59356 (+) Length   422 a.a.
NCBI ID   WP_002886326.1    Uniprot ID   A0AB35IYG6
Organism   Streptococcus salivarius strain MRD6060     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 53088..64356
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJWMD_RS00320 - 53122..53493 (-) 372 Protein_42 DUF3021 domain-containing protein -
  ACJWMD_RS00325 - 53490..53927 (-) 438 WP_002886318.1 LytTR family DNA-binding domain-containing protein -
  ACJWMD_RS00330 - 54106..54411 (+) 306 WP_002886319.1 hypothetical protein -
  ACJWMD_RS00335 mutL 54461..55512 (+) 1052 Protein_45 DNA mismatch repair endonuclease MutL -
  ACJWMD_RS00340 - 55579..56328 (+) 750 Protein_46 DNA mismatch repair protein MutL -
  ACJWMD_RS00345 - 56459..56680 (+) 222 WP_002886321.1 hypothetical protein -
  ACJWMD_RS00350 ruvA 56838..57428 (+) 591 WP_002886323.1 Holliday junction branch migration protein RuvA -
  ACJWMD_RS00355 - 57437..57991 (+) 555 WP_002886325.1 DNA-3-methyladenine glycosylase I -
  ACJWMD_RS00360 cinA 58088..59356 (+) 1269 WP_002886326.1 competence/damage-inducible protein A Machinery gene
  ACJWMD_RS00365 recA 59392..60531 (+) 1140 WP_002886327.1 recombinase RecA Machinery gene
  ACJWMD_RS00370 spx 60698..61096 (+) 399 WP_002886328.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 422 a.a.        Molecular weight: 45683.85 Da        Isoelectric Point: 5.1868

>NTDB_id=1085980 ACJWMD_RS00360 WP_002886326.1 58088..59356(+) (cinA) [Streptococcus salivarius strain MRD6060]
MKAELIAVGTEILTGQITNTNAQFLSEKLAELGIDVYFHTAVGDNESRLLSVLDQASQRSDLVILCGGLGPTEDDLTKQT
LAKFLGKELVFDEEASKKLDSFFATRPKHTRTPNNERQAQIVEGAIPLQNPTGLAVGGIITAQGVTYVVLPGPPSELKPM
VNQELIPALTENHSSLYSRVLRFFGVGESQLVTVLKDFIVNQTDPTIAPYAKVGEVTLRLSTKASSQEEADQKLDVLEKQ
IRSTKTLDGKSLSDFIYGYGESNSLAFEAFRLLKHHGKTITAAESLTAGLFQASIADFSGASQVFKGGFVTYSIEEKAKM
LDIPLSQLEEHGVVSHFTAEKMAEGARAKTDSDYGVALTGVAGPDSLEGHPAGTVFIGIADRNQVRSIKVVIGGRSRSDV
RYISTLYAFNLVRQALLQEDMI

Nucleotide


Download         Length: 1269 bp        

>NTDB_id=1085980 ACJWMD_RS00360 WP_002886326.1 58088..59356(+) (cinA) [Streptococcus salivarius strain MRD6060]
ATGAAAGCTGAATTGATTGCAGTAGGAACTGAAATCCTAACCGGGCAAATCACCAATACCAATGCCCAATTTTTATCTGA
GAAACTAGCTGAACTAGGAATTGACGTGTATTTTCACACAGCAGTAGGAGACAATGAAAGCCGCCTACTTTCAGTTCTTG
ATCAAGCCAGTCAGCGTAGTGATTTAGTCATACTTTGTGGTGGACTTGGCCCTACTGAGGACGACCTAACCAAGCAAACC
CTGGCTAAATTTTTAGGAAAAGAACTCGTTTTTGATGAGGAGGCTAGTAAAAAACTGGATAGTTTCTTTGCTACTCGTCC
TAAACACACACGAACGCCTAATAATGAACGTCAAGCACAAATTGTTGAGGGGGCTATTCCCTTGCAAAACCCGACAGGTC
TTGCAGTTGGAGGGATTATTACTGCTCAAGGGGTGACCTATGTAGTCTTACCTGGTCCACCAAGTGAACTCAAACCTATG
GTGAATCAAGAACTTATTCCAGCTCTTACTGAGAATCACTCAAGTCTTTATTCGAGAGTCCTAAGATTCTTCGGCGTTGG
AGAAAGTCAATTAGTGACTGTTCTTAAGGATTTTATTGTTAACCAAACAGATCCAACCATAGCTCCATACGCTAAAGTGG
GGGAAGTAACACTTCGCTTGTCAACGAAGGCTTCTTCGCAAGAAGAAGCAGATCAAAAACTAGATGTTTTAGAAAAACAA
ATTCGTTCGACTAAAACTCTAGATGGCAAATCCTTATCTGATTTCATTTATGGATATGGAGAGTCTAATAGTTTAGCCTT
TGAAGCTTTTCGTTTGCTTAAGCACCATGGCAAGACCATCACTGCAGCTGAAAGCCTAACAGCAGGTTTATTTCAGGCTA
GTATTGCTGATTTTTCAGGGGCCTCACAAGTATTTAAAGGTGGATTTGTTACTTATAGCATTGAAGAAAAAGCTAAAATG
TTGGATATTCCCTTGTCGCAACTAGAAGAACATGGTGTTGTCAGTCATTTTACTGCAGAAAAAATGGCTGAAGGTGCTCG
AGCTAAAACAGATAGCGATTATGGAGTTGCACTTACCGGTGTAGCTGGACCAGATTCATTAGAAGGACACCCAGCAGGTA
CGGTATTTATTGGTATTGCTGATAGGAATCAAGTAAGGTCAATCAAGGTTGTTATAGGTGGAAGAAGTCGTTCTGATGTT
AGATATATTAGTACCCTCTATGCCTTTAACCTAGTTCGCCAAGCTTTATTACAAGAAGACATGATTTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(264-415)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

75.179

99.289

0.746
  cinA Streptococcus mitis NCTC 12261

74.702

99.289

0.742
  cinA Streptococcus pneumoniae TIGR4

73.747

99.289

0.732
  cinA Streptococcus pneumoniae Rx1

73.508

99.289

0.73
  cinA Streptococcus pneumoniae R6

73.508

99.289

0.73
  cinA Streptococcus pneumoniae D39

73.27

99.289

0.727
  cinA Streptococcus mutans UA159

71.703

98.815

0.709
  cinA Streptococcus suis isolate S10

55.529

98.578

0.547
  cinA Bacillus subtilis subsp. subtilis str. 168

44.893

99.763

0.448

Multiple sequence alignment