Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   ACJPHY_RS22040 Genome accession   NZ_CP176424
Coordinates   4741094..4742311 (+) Length   405 a.a.
NCBI ID   WP_003107299.1    Uniprot ID   -
Organism   Pseudomonas aeruginosa strain IGLPR01     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 4736094..4747311
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJPHY_RS22015 nadC 4736215..4737063 (+) 849 WP_074222678.1 carboxylating nicotinate-nucleotide diphosphorylase -
  ACJPHY_RS22025 - 4737244..4738629 (-) 1386 WP_074222679.1 O-antigen ligase -
  ACJPHY_RS22030 - 4738695..4739159 (-) 465 WP_003111216.1 pilin -
  ACJPHY_RS22035 pilB 4739390..4741090 (+) 1701 WP_034083986.1 type IV-A pilus assembly ATPase PilB Machinery gene
  ACJPHY_RS22040 pilC 4741094..4742311 (+) 1218 WP_003107299.1 type II secretion system F family protein Machinery gene
  ACJPHY_RS22045 pilD 4742312..4743184 (+) 873 WP_023084740.1 type IV prepilin peptidase/methyltransferase PilD Machinery gene
  ACJPHY_RS22050 coaE 4743181..4743792 (+) 612 WP_074222680.1 dephospho-CoA kinase -
  ACJPHY_RS22055 yacG 4743789..4743989 (+) 201 WP_003094656.1 DNA gyrase inhibitor YacG -
  ACJPHY_RS22060 - 4744026..4744235 (-) 210 WP_058355292.1 hypothetical protein -
  ACJPHY_RS22065 - 4744341..4745030 (-) 690 WP_003094662.1 energy-coupling factor ABC transporter permease -
  ACJPHY_RS22070 - 4745027..4745497 (-) 471 WP_003094664.1 hypothetical protein -
  ACJPHY_RS22075 - 4745494..4745919 (-) 426 WP_003103865.1 GNAT family N-acetyltransferase -
  ACJPHY_RS22080 - 4746052..4746681 (+) 630 WP_003094668.1 DUF1780 domain-containing protein -
  ACJPHY_RS22085 - 4746678..4747127 (+) 450 WP_003094670.1 MOSC domain-containing protein -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 44001.86 Da        Isoelectric Point: 9.8103

>NTDB_id=1080106 ACJPHY_RS22040 WP_003107299.1 4741094..4742311(+) (pilC) [Pseudomonas aeruginosa strain IGLPR01]
MADKALKTSVFVWEGTDKKGTKVKGELSSQNPTLVKAQLRKQGITPVKVRKKGISLLGAGKKIKPMDIALFTRQMSTMMA
AGVPLLQSFDIISEGFDNPNMRKLVEEIKQEVAGGNSLANSLRKKPQYFDSLYCNLVDAGEQSGALETLLDRVATYKEKT
EALKAKIKKAMTYPIAVIVVAIIVSAILLIKVVPQFQSVFEGFGAELPAFTMMVINISNVLQEWWLLVLLMMGGAGFLLN
HAYKRSEKFRDATDRTVLKLPIVGAILYKSAVARYARTLSTTFAAGVPLVEALDSVSGATGNVVFRDAVGKIKQDVSTGM
QLNFSMRTTNIFPSMAIQMTAIGEESGALDDMLAKVAGFYEQEVDNAVDNLTALMEPMIMAVLGVLVGGLIIAMYLPIFQ
LGNVV

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=1080106 ACJPHY_RS22040 WP_003107299.1 4741094..4742311(+) (pilC) [Pseudomonas aeruginosa strain IGLPR01]
ATGGCGGACAAAGCGTTAAAGACCAGTGTCTTCGTATGGGAAGGCACTGACAAGAAAGGCACCAAGGTCAAGGGCGAGCT
GTCCAGCCAGAACCCGACCCTGGTCAAGGCGCAACTGCGCAAGCAGGGCATCACGCCGGTCAAGGTCCGCAAGAAAGGCA
TTTCCCTGCTGGGGGCGGGGAAGAAGATCAAGCCTATGGACATCGCCCTGTTCACCCGCCAGATGTCCACCATGATGGCC
GCCGGCGTGCCGCTGCTGCAGTCGTTCGACATCATCAGCGAAGGCTTCGACAATCCGAACATGCGCAAGCTGGTGGAGGA
GATCAAGCAGGAAGTCGCCGGCGGCAACAGCCTGGCCAACTCGCTGCGCAAGAAGCCGCAGTACTTCGACTCGCTCTACT
GCAACCTGGTGGACGCCGGCGAACAATCCGGCGCCCTGGAAACTCTGCTCGACCGGGTCGCCACCTACAAGGAAAAGACC
GAGGCGCTGAAGGCCAAGATCAAGAAGGCCATGACCTACCCGATCGCGGTGATCGTCGTCGCCATCATCGTTTCGGCGAT
CCTACTGATCAAGGTGGTGCCGCAGTTCCAGTCGGTGTTCGAGGGCTTCGGCGCCGAACTGCCAGCCTTCACCATGATGG
TCATCAACATTTCCAACGTACTCCAGGAATGGTGGCTCCTGGTACTGCTGATGATGGGCGGCGCCGGCTTCCTGCTGAAC
CACGCCTACAAGCGTTCGGAGAAGTTCCGCGACGCCACCGACCGCACGGTACTGAAGCTGCCGATCGTCGGCGCCATCCT
CTACAAATCCGCCGTGGCACGCTACGCGCGGACGCTGTCGACCACCTTCGCCGCCGGCGTGCCATTGGTGGAAGCCCTCG
ACTCGGTTTCCGGCGCCACCGGCAACGTGGTGTTCAGGGACGCGGTGGGCAAGATCAAGCAGGACGTGTCCACCGGCATG
CAGCTGAACTTCTCCATGCGCACCACCAACATCTTTCCCAGCATGGCCATCCAGATGACCGCCATCGGCGAGGAATCGGG
CGCGCTGGACGACATGCTGGCCAAGGTCGCTGGCTTCTACGAGCAGGAAGTGGATAATGCCGTGGACAACCTGACCGCCC
TGATGGAACCAATGATCATGGCGGTCCTCGGGGTCCTGGTCGGTGGCCTGATCATCGCCATGTACCTGCCGATCTTCCAG
TTGGGCAACGTCGTCTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(276-397)

Type II secretion system (T2SS), protein F (T2SSF)

(71-194)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

78.765

100

0.788
  pilC Acinetobacter baylyi ADP1

61.029

100

0.615
  pilC Acinetobacter baumannii D1279779

60.396

99.753

0.602
  pilC Legionella pneumophila strain ERS1305867

54.293

97.778

0.531
  pilG Neisseria gonorrhoeae MS11

46.04

99.753

0.459
  pilG Neisseria meningitidis 44/76-A

45.522

99.259

0.452
  pilC Vibrio cholerae strain A1552

41.481

100

0.415
  pilC Vibrio campbellii strain DS40M4

40.648

99.012

0.402
  pilC Thermus thermophilus HB27

38.155

99.012

0.378

Multiple sequence alignment