Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   ACKWPP_RS04205 Genome accession   NZ_CP176418
Coordinates   773462..774124 (+) Length   220 a.a.
NCBI ID   WP_409374248.1    Uniprot ID   -
Organism   Streptococcus suis strain KKAHC02     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 768462..779124
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACKWPP_RS04185 (ACKWPP_04185) - 769179..770108 (-) 930 WP_012775038.1 ABC transporter substrate-binding protein -
  ACKWPP_RS04190 (ACKWPP_04190) - 770105..770905 (-) 801 WP_409374246.1 ABC transporter ATP-binding protein -
  ACKWPP_RS04195 (ACKWPP_04195) - 771057..772502 (-) 1446 WP_409374247.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  ACKWPP_RS04200 (ACKWPP_04200) - 772649..773395 (+) 747 WP_014735985.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  ACKWPP_RS04205 (ACKWPP_04205) comEA/celA/cilE 773462..774124 (+) 663 WP_409374248.1 helix-hairpin-helix domain-containing protein Machinery gene
  ACKWPP_RS04210 (ACKWPP_04210) comEC/celB 774108..776345 (+) 2238 WP_409374249.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ACKWPP_RS04215 (ACKWPP_04215) holA 776441..777472 (+) 1032 WP_024390246.1 DNA polymerase III subunit delta -
  ACKWPP_RS04220 (ACKWPP_04220) sodA 777585..778190 (+) 606 WP_013730459.1 superoxide dismutase SodA -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23348.03 Da        Isoelectric Point: 4.1234

>NTDB_id=1080059 ACKWPP_RS04205 WP_409374248.1 773462..774124(+) (comEA/celA/cilE) [Streptococcus suis strain KKAHC02]
MDTIKTYIEMLKEYKWQIALPAVAGLLMGTFLIFSQPAKSDQTGLTDFPQTEQTSSSSDLVEKNSTEVSEEPSQLVVDVK
GAVAKPGLYTLEADARVNDAVEAAGGLTSQADPKSINLAQKLSDEAVVYVASKDENISVVASTTANSAMSPEEKSTSLVN
LNTATEADLQTISGIGAKRAADIIAYRESNGGFKSVDDLNNVSGIGDKTMESIRPYVTVD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=1080059 ACKWPP_RS04205 WP_409374248.1 773462..774124(+) (comEA/celA/cilE) [Streptococcus suis strain KKAHC02]
ATGGATACGATTAAAACTTATATAGAAATGCTTAAAGAATATAAGTGGCAAATTGCTCTGCCAGCAGTGGCTGGCTTGCT
AATGGGGACGTTCTTAATCTTCAGTCAACCAGCCAAGTCTGACCAGACAGGACTGACAGATTTTCCGCAGACCGAACAAA
CTTCTAGTAGCTCTGACTTGGTCGAGAAAAACAGTACAGAAGTAAGTGAGGAACCCAGCCAGCTGGTCGTTGATGTCAAA
GGAGCAGTAGCAAAGCCGGGACTCTACACTTTAGAAGCTGATGCGCGTGTTAATGATGCAGTTGAAGCAGCTGGCGGCTT
GACCAGTCAGGCAGACCCCAAGTCTATCAATCTGGCTCAGAAGCTCAGCGATGAGGCGGTGGTCTATGTGGCCAGCAAGG
ATGAAAATATCTCGGTGGTGGCCAGCACGACTGCCAACTCTGCTATGTCCCCAGAAGAAAAAAGCACCAGTCTGGTCAAT
CTGAATACGGCGACCGAGGCGGACCTGCAGACCATTTCGGGCATCGGTGCCAAGCGGGCGGCGGACATTATCGCCTATCG
CGAGTCCAATGGTGGCTTCAAGTCGGTGGACGACCTCAACAATGTTTCGGGCATCGGCGACAAGACTATGGAAAGCATCC
GGCCTTATGTCACGGTCGATTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(157-218)

SLBB domain (SLBB)

(76-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae Rx1

48.402

99.545

0.482
  comEA/celA/cilE Streptococcus pneumoniae D39

48.402

99.545

0.482
  comEA/celA/cilE Streptococcus pneumoniae R6

48.402

99.545

0.482
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

48.402

99.545

0.482
  comEA/celA/cilE Streptococcus mitis SK321

47.085

100

0.477
  comEA/celA/cilE Streptococcus mitis NCTC 12261

46.789

99.091

0.464
  comEA Streptococcus thermophilus LMD-9

59.259

73.636

0.436
  comEA Lactococcus lactis subsp. cremoris KW2

40.09

100

0.405
  comEA Bacillus subtilis subsp. subtilis str. 168

38.571

95.455

0.368

Multiple sequence alignment