Detailed information NTG1080060

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: ACKWPP_RS04210
• Genome accession: NZ_CP176418
• Coordinates: 774108..776345 (+)
• Length: 745 a.a.
• NCBI ID: WP_409374249.1
• Uniprot ID: -
• Organism: Streptococcus suis strain KKAHC02
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 769108..781345

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACKWPP_RS04185 (ACKWPP_04185)	-	769179..770108 (-)	930	WP_012775038.1	ABC transporter substrate-binding protein	-
ACKWPP_RS04190 (ACKWPP_04190)	-	770105..770905 (-)	801	WP_409374246.1	ABC transporter ATP-binding protein	-
ACKWPP_RS04195 (ACKWPP_04195)	-	771057..772502 (-)	1446	WP_409374247.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
ACKWPP_RS04200 (ACKWPP_04200)	-	772649..773395 (+)	747	WP_014735985.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
ACKWPP_RS04205 (ACKWPP_04205)	comEA/celA/cilE	773462..774124 (+)	663	WP_409374248.1	helix-hairpin-helix domain-containing protein	Machinery gene
ACKWPP_RS04210 (ACKWPP_04210)	comEC/celB	774108..776345 (+)	2238	WP_409374249.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ACKWPP_RS04215 (ACKWPP_04215)	holA	776441..777472 (+)	1032	WP_024390246.1	DNA polymerase III subunit delta	-
ACKWPP_RS04220 (ACKWPP_04220)	sodA	777585..778190 (+)	606	WP_013730459.1	superoxide dismutase SodA	-
ACKWPP_RS04225 (ACKWPP_04225)	-	778454..780466 (+)	2013	WP_409374250.1	bifunctional metallophosphatase/5'-nucleotidase	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 83987.81 Da
• Isoelectric Point: 6.6712

>NTDB_id=1080060 ACKWPP_RS04210 WP_409374249.1 774108..776345(+) (comEC/celB) [Streptococcus suis strain KKAHC02]
MSRSIKLPCQPIHLAILAVAAYFAVHSFSLLTMGLLSLLLLVFGFRQGKAVFIKTLPLLALCGLFFGCQKVQWERAAQSP
QEQVTAVQVIPDTIEVNGDNLSFRGRADGQTYQVFYNLASQEEQAYFQKLADLVQLEVEAEVSLPAGQRNFKGFDYQAYL
KTQGIYRTVKITAIKKIVPIQSWNVFDWLSSWRRQALVYVKTNFPAPMSHYMTGLLFGDLDSEFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKEAVDKLQIPFSIVYAGLTGFSVSVVRSLVQKILGNMGLRKLDNFAVTVFVCLLIL
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPILMTYFYAFQPLSILMTFVFSFVFDVLLLPGLSV
IFLLSPLVKMTWVNGFFVFMEKIIVWVADLGFRPWILGKPSELVLLLLLVSLFLLYDFHRKKNWLLGLSLVLALLFFITK
HPLENEVTVVDIGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEAWQERSSQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVQIGRIVVSPGSLTVPDFVATLKEINVPVHVVKVGDRLPIFDAYLEVLYPDGTGDGGNNDSIVLYGRLL
ETNFLFTGDLEQGELDLIETYPNLPVDVLKAGHHGSKGSSYPEFLDHIEAKIALISAGENNRYKHPHQETLDRFDSRNIQ
VYRTDQQGAIRFRGWREWRIETVRE

Nucleotide

• Length: 2238 bp

>NTDB_id=1080060 ACKWPP_RS04210 WP_409374249.1 774108..776345(+) (comEC/celB) [Streptococcus suis strain KKAHC02]
ATGTCACGGTCGATTAAGCTCCCCTGCCAGCCCATTCACCTGGCAATCTTGGCGGTGGCGGCCTACTTTGCAGTCCACTC
TTTTTCCCTGTTGACAATGGGCCTGCTGAGTTTATTGTTGCTGGTCTTTGGATTTCGGCAAGGTAAGGCAGTGTTCATCA
AAACGCTGCCGCTTCTAGCCCTATGTGGTCTCTTTTTCGGATGCCAAAAGGTCCAATGGGAGAGGGCAGCCCAGTCACCC
CAAGAGCAAGTCACAGCTGTTCAGGTCATTCCAGATACCATTGAAGTCAACGGGGACAATCTGTCTTTTCGCGGTCGGGC
TGACGGACAAACCTATCAGGTGTTCTACAACTTAGCCAGTCAGGAGGAGCAGGCTTATTTTCAAAAGCTAGCAGACCTGG
TCCAGCTAGAAGTGGAAGCAGAGGTCAGCCTGCCAGCTGGTCAGCGGAATTTCAAGGGCTTTGACTACCAAGCCTATCTG
AAAACGCAGGGAATTTATCGGACAGTCAAGATAACTGCGATCAAGAAGATTGTCCCTATCCAGTCTTGGAATGTTTTTGA
CTGGCTATCAAGCTGGCGGAGGCAAGCCTTGGTCTATGTCAAAACCAATTTTCCGGCTCCCATGAGCCACTACATGACAG
GGCTCTTGTTTGGGGACTTGGATAGTGAGTTTGACCAGATGAGTGATCTCTATTCTAGTTTAGGAATCATTCATCTCTTT
GCCCTGTCTGGTATGCAAGTTGGATTTTTCATCGATAAGTTTCGCTGGATTTTACTGCGTTTGGGCTTGACCAAGGAAGC
CGTAGATAAGTTACAGATTCCCTTTTCCATTGTTTATGCTGGTTTGACAGGCTTTTCTGTGTCGGTTGTGCGGTCCTTGG
TCCAGAAAATTCTGGGCAATATGGGCTTGCGGAAGTTGGATAACTTTGCGGTGACAGTTTTTGTCTGTCTGCTGATTCTG
CCCCGATTTTTACTGACAGCAGGAGGAGTGCTGACTTTTACCTATGCTTTCTTGCTGACGGTCTTTGATTTTGAGGATTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAGAGCCTCAGTATTTCGCTGGGAATTTTGCCGATTCTCATGACCTATTTCTATG
CCTTCCAGCCCTTGTCTATTCTCATGACCTTTGTCTTTTCCTTTGTCTTTGATGTCCTGCTTTTGCCAGGTTTGTCGGTC
ATTTTTCTCCTCTCACCCTTGGTCAAGATGACCTGGGTCAACGGATTTTTTGTCTTTATGGAAAAAATCATTGTCTGGGT
GGCTGATTTGGGTTTTCGGCCTTGGATACTGGGCAAGCCGTCTGAGCTGGTCCTCTTGCTTTTGCTGGTCAGCCTCTTCT
TACTTTATGATTTCCACAGGAAGAAAAACTGGCTTCTAGGACTGAGCTTGGTCCTCGCTCTGCTATTTTTCATCACCAAA
CACCCGCTGGAAAACGAGGTGACGGTGGTGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTTCTGATTGATGTGGGCGGTCGGGTAGATTTTGCGGCCAAGGAAGCGTGGCAGGAGCGGTCTTCGCAGGCAAATGCAG
AGCGGACATTGATTCCCTATCTGCATAGTCGGGGTGTGGATAGGATTGATAGCTTGGTTCTGACCCATACCGACACAGAC
CATGTGGGCGATGTGCTGGAAGTGGCTAAGCAGGTGCAAATTGGTCGGATTGTCGTGTCGCCGGGAAGTCTGACGGTGCC
TGACTTTGTAGCAACCTTGAAAGAAATCAATGTCCCTGTTCATGTGGTCAAAGTGGGTGACCGCTTGCCGATTTTTGACG
CCTATCTGGAAGTCCTCTATCCAGATGGGACAGGCGACGGTGGTAATAACGACTCTATTGTTCTTTACGGTCGCTTGTTG
GAAACTAACTTTCTCTTTACAGGAGACCTGGAGCAAGGGGAGTTGGACTTGATAGAAACCTATCCCAACCTGCCTGTCGA
TGTCCTCAAAGCCGGTCACCACGGCTCCAAAGGTTCTTCCTATCCTGAATTTTTGGACCATATCGAAGCCAAGATTGCCT
TGATATCTGCAGGAGAAAATAACCGCTACAAGCATCCTCATCAAGAAACCTTGGACCGCTTTGACAGTCGGAATATCCAA
GTCTATCGTACCGACCAGCAAGGAGCCATCCGCTTCCGAGGTTGGAGGGAGTGGAGGATTGAAACGGTGAGGGAGTAA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-698)

• Competence protein (Competence) (215-460)

• Domain of unknown function (DUF4131) (DUF4131) (28-175)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	53.836	99.732	0.537
comEC/celB	Streptococcus mitis NCTC 12261	52.767	99.463	0.525
comEC/celB	Streptococcus pneumoniae TIGR4	52.156	99.597	0.519
comEC/celB	Streptococcus pneumoniae Rx1	51.887	99.597	0.517
comEC/celB	Streptococcus pneumoniae D39	51.887	99.597	0.517
comEC/celB	Streptococcus pneumoniae R6	51.887	99.597	0.517
comEC	Lactococcus lactis subsp. cremoris KW2	48.529	100	0.487