Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   ACI7YU_RS22165 Genome accession   NZ_CP173722
Coordinates   4999540..5000757 (+) Length   405 a.a.
NCBI ID   WP_150638505.1    Uniprot ID   A0A5E7NZ39
Organism   Pseudomonas siliginis strain P     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 4994540..5005757
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACI7YU_RS22145 (ACI7YU_22155) - 4995975..4996274 (+) 300 WP_406227480.1 DUF2845 domain-containing protein -
  ACI7YU_RS22150 (ACI7YU_22160) - 4996539..4996892 (-) 354 WP_071173629.1 BON domain-containing protein -
  ACI7YU_RS22155 (ACI7YU_22165) pilA/pilAI 4997188..4997610 (-) 423 WP_252876912.1 pilin Machinery gene
  ACI7YU_RS22160 (ACI7YU_22170) pilB 4997837..4999537 (+) 1701 WP_056790439.1 type IV-A pilus assembly ATPase PilB Machinery gene
  ACI7YU_RS22165 (ACI7YU_22175) pilC 4999540..5000757 (+) 1218 WP_150638505.1 type II secretion system F family protein Machinery gene
  ACI7YU_RS22170 (ACI7YU_22180) pilD 5000759..5001631 (+) 873 WP_256811000.1 A24 family peptidase Machinery gene
  ACI7YU_RS22175 (ACI7YU_22185) coaE 5001628..5002251 (+) 624 WP_076564149.1 dephospho-CoA kinase -
  ACI7YU_RS22180 (ACI7YU_22190) yacG 5002248..5002448 (+) 201 WP_016773149.1 DNA gyrase inhibitor YacG -
  ACI7YU_RS22185 (ACI7YU_22195) - 5002456..5002671 (-) 216 WP_016773148.1 hypothetical protein -
  ACI7YU_RS22190 (ACI7YU_22200) - 5002737..5003426 (-) 690 WP_130887102.1 energy-coupling factor ABC transporter permease -
  ACI7YU_RS22195 (ACI7YU_22205) - 5003617..5004243 (+) 627 WP_007909887.1 DUF1780 domain-containing protein -
  ACI7YU_RS22200 (ACI7YU_22210) - 5004240..5004767 (+) 528 WP_056790453.1 MOSC domain-containing protein -
  ACI7YU_RS22205 (ACI7YU_22215) - 5004819..5004992 (+) 174 WP_007909875.1 DUF3094 domain-containing protein -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 44057.75 Da        Isoelectric Point: 10.1214

>NTDB_id=1073837 ACI7YU_RS22165 WP_150638505.1 4999540..5000757(+) (pilC) [Pseudomonas siliginis strain P]
MAVKAAKVSIYAWEGTDRKGSKVSGELSGQNPALIKAQLRKQGINPGKVRKKSASLLTFGKRIKPQDIALFTRQMATMMK
AGVPLLQSFDIIGEGFENPAMRKLVDEVKQEVAAGNSFATALRKKPQYFDELYCNLVDAGEQSGALDTLLERVATYKEKS
EALKAKIKKAMTYPTAVVLVAAVVTGILLVKVVPQFQSVFSGFGAELPGFTLMIISLSEFMQQWWWAILFALVAAFFGTR
HALKTSQALRDRRDAWLLKLPLVGTLMYKSAVARFARTLSTTFAAGVPLVEALDSVAGATGNVVFKRAVLRVRQDVSTGM
QLNFSMRSTGVFPNMAVQMTAIGEESGALDDMLDKVAGFYEAEVDNMVDNLTSLMEPFIMVVLGVIVGGLVVAMYLPIFQ
LGSAI

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=1073837 ACI7YU_RS22165 WP_150638505.1 4999540..5000757(+) (pilC) [Pseudomonas siliginis strain P]
ATGGCGGTCAAGGCAGCGAAAGTCAGCATTTACGCCTGGGAAGGCACGGACCGCAAAGGCAGTAAAGTCAGCGGCGAGTT
GAGCGGACAGAACCCCGCACTGATCAAGGCGCAACTGCGCAAACAGGGGATCAACCCGGGCAAGGTGCGCAAGAAATCCG
CGTCCCTGCTGACCTTCGGCAAACGCATCAAACCGCAGGACATCGCCCTGTTCACCCGGCAGATGGCGACCATGATGAAG
GCCGGCGTGCCGCTGTTGCAGTCCTTCGACATCATCGGCGAAGGCTTCGAAAACCCGGCCATGCGCAAACTGGTCGACGA
GGTCAAACAGGAGGTCGCGGCCGGTAACAGCTTCGCTACGGCCCTGCGCAAGAAGCCGCAATACTTCGACGAGTTGTACT
GCAACCTGGTCGACGCCGGCGAACAGTCTGGCGCCCTCGACACCTTGCTTGAACGTGTGGCGACCTATAAGGAAAAAAGC
GAAGCGCTCAAGGCCAAGATCAAGAAAGCCATGACCTACCCCACCGCCGTGGTGCTGGTGGCGGCAGTGGTAACAGGCAT
TCTGCTGGTCAAGGTGGTGCCGCAGTTCCAGTCGGTATTCTCCGGGTTCGGCGCCGAACTGCCGGGCTTCACCCTGATGA
TCATCAGCCTGTCGGAATTCATGCAGCAGTGGTGGTGGGCGATTCTTTTTGCGCTGGTGGCAGCGTTTTTCGGCACTCGC
CACGCGTTGAAGACATCCCAGGCCCTGCGCGACCGTCGCGATGCCTGGCTGCTGAAGCTGCCACTGGTGGGCACCTTGAT
GTACAAGTCCGCCGTCGCACGTTTTGCCCGCACCCTGTCGACCACATTCGCAGCCGGTGTGCCGCTGGTGGAAGCACTGG
ATTCGGTCGCCGGTGCCACCGGCAATGTGGTGTTCAAGCGCGCGGTGTTGCGGGTGCGGCAGGACGTCTCGACCGGCATG
CAACTGAATTTCTCCATGCGCAGCACCGGTGTGTTTCCCAACATGGCGGTGCAGATGACCGCCATCGGCGAGGAATCGGG
CGCGCTGGATGACATGCTCGACAAGGTCGCCGGTTTTTATGAAGCGGAAGTCGATAACATGGTCGACAACCTCACCAGCC
TGATGGAGCCGTTCATCATGGTGGTGCTGGGGGTCATCGTCGGTGGACTGGTGGTGGCCATGTACCTGCCGATCTTCCAG
CTCGGCTCAGCGATCTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(275-397)

Type II secretion system (T2SS), protein F (T2SSF)

(71-194)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5E7NZ39

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

73.827

100

0.738
  pilC Acinetobacter baylyi ADP1

58.578

100

0.59
  pilC Acinetobacter baumannii D1279779

58.578

100

0.59
  pilC Legionella pneumophila strain ERS1305867

52.75

98.765

0.521
  pilC Vibrio cholerae strain A1552

44.697

97.778

0.437
  pilG Neisseria gonorrhoeae MS11

43.424

99.506

0.432
  pilG Neisseria meningitidis 44/76-A

42.68

99.506

0.425
  pilC Vibrio campbellii strain DS40M4

41.872

100

0.42
  pilC Thermus thermophilus HB27

39.348

98.519

0.388

Multiple sequence alignment