Detailed information NTG1070812

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: ACIVIR_RS06445
• Genome accession: NZ_CP173225
• Coordinates: 1238654..1239304 (+)
• Length: 216 a.a.
• NCBI ID: WP_114880828.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 262
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1233654..1244304

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACIVIR_RS06415	-	1234138..1234353 (+)	216	WP_001232082.1	YozE family protein	-
ACIVIR_RS06420	-	1234439..1235407 (+)	969	WP_000658183.1	PhoH family protein	-
ACIVIR_RS06425	-	1235600..1236100 (+)	501	WP_000566982.1	GNAT family N-acetyltransferase	-
ACIVIR_RS06430	-	1236103..1236428 (+)	326	Protein_1225	TfoX/Sxy family protein	-
ACIVIR_RS06435	ald	1236729..1237840 (-)	1112	Protein_1226	alanine dehydrogenase	-
ACIVIR_RS06440	-	1238017..1238586 (+)	570	WP_114880827.1	GNAT family N-acetyltransferase	-
ACIVIR_RS06445	comEA/celA/cilE	1238654..1239304 (+)	651	WP_114880828.1	helix-hairpin-helix domain-containing protein	Machinery gene
ACIVIR_RS06450	comEC/celB	1239288..1241528 (+)	2241	WP_044727637.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ACIVIR_RS06455	-	1241707..1241895 (+)	189	WP_001809102.1	hypothetical protein	-
ACIVIR_RS06460	-	1241927..1242514 (+)	588	WP_000933542.1	ATP-binding cassette domain-containing protein	-
ACIVIR_RS06465	-	1242518..1243698 (+)	1181	Protein_1232	hypothetical protein	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23274.65 Da
• Isoelectric Point: 6.0746

>NTDB_id=1070812 ACIVIR_RS06445 WP_114880828.1 1238654..1239304(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain 262]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNVQAEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSISKEKKVNLNKA
SLEELKQVKRLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=1070812 ACIVIR_RS06445 WP_114880828.1 1238654..1239304(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain 262]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGCGGATT
TTTCCTGCTAAAGCCAGCTCCACAAACACCTGTAAAGGAAACGAATGTGCAGGCTGAAGTTGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAGAAGGAAGAACCAGTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGTCAACAGACTGGTTCGGGGACAGCTTCTTCAATAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGAGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (151-214)

• SLBB domain (SLBB) (76-126)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae Rx1	98.148	100	0.981
comEA/celA/cilE	Streptococcus pneumoniae D39	98.148	100	0.981
comEA/celA/cilE	Streptococcus pneumoniae R6	98.148	100	0.981
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	96.296	100	0.963
comEA/celA/cilE	Streptococcus mitis NCTC 12261	94.907	100	0.949
comEA/celA/cilE	Streptococcus mitis SK321	90.278	100	0.903
comEA	Lactococcus lactis subsp. cremoris KW2	43.172	100	0.454
comEA	Streptococcus thermophilus LMD-9	39.738	100	0.421
comEA	Bacillus subtilis subsp. subtilis str. 168	41.053	87.963	0.361