Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ACFSN5_RS10030 Genome accession   NZ_CP172427
Coordinates   2172775..2174046 (-) Length   423 a.a.
NCBI ID   WP_165212935.1    Uniprot ID   -
Organism   Streptococcus sp. ZJ 1593     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2167775..2179046
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACFSN5_RS09995 (ACFSN5_09995) - 2168637..2168762 (-) 126 WP_277423774.1 hypothetical protein -
  ACFSN5_RS10000 (ACFSN5_10000) - 2168872..2169171 (-) 300 WP_165212927.1 DUF1292 domain-containing protein -
  ACFSN5_RS10005 (ACFSN5_10005) ruvX 2169186..2169605 (-) 420 WP_004226676.1 Holliday junction resolvase RuvX -
  ACFSN5_RS10010 (ACFSN5_10010) - 2169605..2169871 (-) 267 WP_002960554.1 IreB family regulatory phosphoprotein -
  ACFSN5_RS10015 (ACFSN5_10015) - 2170057..2170647 (-) 591 WP_165212929.1 SP0191 family lipoprotein -
  ACFSN5_RS10020 (ACFSN5_10020) spx 2170851..2171249 (-) 399 WP_165212931.1 transcriptional regulator Spx -
  ACFSN5_RS10025 (ACFSN5_10025) recA 2171599..2172741 (-) 1143 WP_165212933.1 recombinase RecA Machinery gene
  ACFSN5_RS10030 (ACFSN5_10030) cinA 2172775..2174046 (-) 1272 WP_165212935.1 competence/damage-inducible protein A Machinery gene
  ACFSN5_RS10035 (ACFSN5_10035) - 2174272..2176185 (+) 1914 WP_165212937.1 ATP-binding cassette domain-containing protein -
  ACFSN5_RS10040 (ACFSN5_10040) - 2176624..2177181 (-) 558 WP_165212939.1 DNA-3-methyladenine glycosylase I -
  ACFSN5_RS10045 (ACFSN5_10045) ruvA 2177355..2177945 (-) 591 WP_165212941.1 Holliday junction branch migration protein RuvA -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45722.09 Da        Isoelectric Point: 4.5999

>NTDB_id=1067697 ACFSN5_RS10030 WP_165212935.1 2172775..2174046(-) (cinA) [Streptococcus sp. ZJ 1593]
MKAEIIAVGTEILTGQIVNTNAQFLSEKFAELGIDVYFQTAVGDNEERLLSLLDLASQRSDMIVLCGGLGPTDDDLTKQT
LAKFLKRPLVFDDQAMDKLNRFFAARPAVLRTSNNERQAQTIEGALPLQNRTGLAVGGLIEVEEKTYIVLPGPPSELKPM
VQEQLLPLIDQDHQQLYSRVLRFFGIGESQLVTVIDDFIKNQTDPTIAPYAKTGEVTLRLSTKARSQEEAEQKLDQLEAA
LMAVQSLENQPLSSYFYGYGDDNSLAQVTFDLLKSSGKTITAAESLTAGLFQASLADFSGASAVFNGGFVTYSMEEKSKM
LGIPLVDLQAHGVISAFTAEAMAAGARSKTEADLAISLTGVAGPDSLEGQPAGTVFIGLATANSLESHLVKMSGRSRSDV
REIAVLHAFNLVRKALLKEKNLV

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=1067697 ACFSN5_RS10030 WP_165212935.1 2172775..2174046(-) (cinA) [Streptococcus sp. ZJ 1593]
ATGAAAGCTGAAATAATTGCAGTCGGAACAGAAATTTTAACAGGGCAAATCGTCAATACCAATGCGCAATTTCTCTCAGA
AAAATTTGCCGAGCTGGGGATTGATGTTTATTTCCAGACAGCTGTTGGTGATAATGAGGAACGCCTCTTGTCTCTTCTTG
ATCTCGCCAGCCAACGAAGTGATATGATTGTGCTCTGTGGAGGTTTGGGACCAACGGATGATGATTTAACTAAACAAACC
TTAGCTAAGTTTCTCAAGCGTCCCTTAGTTTTTGATGATCAGGCTATGGACAAGCTGAATCGTTTCTTTGCGGCTCGTCC
TGCAGTCTTGCGGACGTCCAATAATGAACGTCAGGCTCAAACCATAGAAGGAGCCCTTCCTCTTCAAAACCGCACAGGTC
TTGCAGTTGGAGGTCTGATTGAAGTTGAGGAAAAGACCTACATCGTCCTACCTGGTCCGCCGAGCGAACTCAAGCCTATG
GTTCAGGAGCAACTCTTGCCTTTAATTGATCAGGATCATCAGCAGCTCTATTCTCGCGTTTTGCGTTTCTTTGGAATCGG
TGAAAGCCAGTTAGTGACGGTTATTGATGATTTCATTAAAAACCAAACTGACCCTACCATCGCTCCTTATGCAAAGACAG
GGGAAGTCACTCTGCGTCTTTCTACCAAGGCCCGGAGTCAAGAAGAAGCAGAGCAAAAATTAGATCAGCTCGAAGCAGCC
CTAATGGCGGTTCAATCGCTAGAAAATCAACCCCTATCTAGTTATTTTTATGGTTATGGGGATGATAATTCTCTGGCCCA
AGTTACCTTTGATTTGCTCAAGAGCTCTGGCAAGACAATCACGGCAGCAGAAAGTCTGACAGCGGGCTTGTTCCAAGCTA
GTTTAGCAGACTTTTCTGGAGCTTCAGCTGTTTTTAACGGTGGCTTTGTCACCTACAGTATGGAAGAAAAGTCCAAAATG
CTAGGGATTCCTTTGGTTGACCTGCAAGCTCATGGCGTCATTTCAGCTTTTACAGCAGAAGCTATGGCTGCTGGTGCCAG
AAGCAAGACTGAGGCAGATTTAGCTATCTCGCTGACTGGGGTTGCGGGACCTGATAGCTTGGAAGGTCAACCGGCAGGGA
CGGTTTTCATTGGTCTAGCTACAGCAAACAGCTTAGAAAGTCACCTTGTAAAAATGAGTGGCCGTTCCCGCAGCGATGTG
CGTGAGATTGCAGTCTTGCATGCCTTTAATCTGGTACGAAAAGCTTTATTAAAGGAGAAAAATTTAGTATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-242)

Competence-damaged protein (CinA)

(263-415)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

71.868

100

0.719
  cinA Streptococcus mitis SK321

70.883

99.054

0.702
  cinA Streptococcus mitis NCTC 12261

70.167

99.054

0.695
  cinA Streptococcus pneumoniae TIGR4

69.451

99.054

0.688
  cinA Streptococcus pneumoniae Rx1

69.451

99.054

0.688
  cinA Streptococcus pneumoniae R6

69.451

99.054

0.688
  cinA Streptococcus pneumoniae D39

69.212

99.054

0.686
  cinA Streptococcus suis isolate S10

55.529

98.345

0.546
  cinA Bacillus subtilis subsp. subtilis str. 168

45.735

99.764

0.456

Multiple sequence alignment