Detailed information NTG0106582

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: AABJ45_RS04625
• Genome accession: NZ_AP028611
• Coordinates: 911336..913576 (+)
• Length: 746 a.a.
• NCBI ID: WP_000942416.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain Sep6
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 906336..918576

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AABJ45_RS04595 (TKY121527_09120)	-	906510..907478 (+)	969	WP_000658183.1	PhoH family protein	-
AABJ45_RS04600 (TKY121527_09130)	-	907671..908171 (+)	501	WP_000566985.1	GNAT family N-acetyltransferase	-
AABJ45_RS04605 (TKY121527_09140)	-	908174..908500 (+)	327	Protein_908	TfoX/Sxy family protein	-
AABJ45_RS04610 (TKY121527_09160)	ald	908801..909888 (-)	1088	Protein_909	alanine dehydrogenase	-
AABJ45_RS04615 (TKY121527_09170)	-	910065..910634 (+)	570	WP_000443745.1	GNAT family N-acetyltransferase	-
AABJ45_RS04620 (TKY121527_09180)	comEA/celA/cilE	910702..911352 (+)	651	WP_000387346.1	helix-hairpin-helix domain-containing protein	Machinery gene
AABJ45_RS04625 (TKY121527_09190)	comEC/celB	911336..913576 (+)	2241	WP_000942416.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
AABJ45_RS04630	-	913725..913942 (+)	218	Protein_913	hypothetical protein	-
AABJ45_RS04635 (TKY121527_09200)	-	913975..914562 (+)	588	WP_000939883.1	ABC transporter ATP-binding protein	-
AABJ45_RS04640 (TKY121527_09210)	-	914566..915747 (+)	1182	WP_000655941.1	hypothetical protein	-
AABJ45_RS04645 (TKY121527_09220)	infC	916054..916584 (+)	531	WP_000848180.1	translation initiation factor IF-3	-
AABJ45_RS04650 (TKY121527_09230)	rpmI	916617..916817 (+)	201	WP_001125943.1	50S ribosomal protein L35	-
AABJ45_RS04655 (TKY121527_09240)	rplT	916869..917228 (+)	360	WP_000124836.1	50S ribosomal protein L20	-
AABJ45_RS04660 (TKY121527_09250)	-	917286..917666 (+)	381	WP_000157154.1	VOC family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84512.01 Da
• Isoelectric Point: 9.6237

>NTDB_id=106582 AABJ45_RS04625 WP_000942416.1 911336..913576(+) (comEC/celB) [Streptococcus pneumoniae strain Sep6]
MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCLFFQFPWKSASKVLVICGIFGFWFVFQNWQQSQASQN
LADSVEGVRILPDTIKVNGDSLSFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIV
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLTFLPLLSI
LFVLSFLYPVIQLNFIFEWLEGIIRLVSQVARRPLVFGQPNAWLLILLLISLALVYDLRKNIKGLTVLSLLITGLFFLTK
YPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESYKKIEKWQEKMTTSNAQRSLIPYLKSRGVAKIDQLILTNTDK
EHVGDLLEVTKAFHVGEILVSKGSLKQKQFVVELQATQTKVRSMTVGENLPIFGSQLEVLSLRKMGDGGHDDTLVLYGKF
LDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSSSPTFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGIN
SKVYRTDQQGAIRFKGLDSWKIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=106582 AABJ45_RS04625 WP_000942416.1 911336..913576(+) (comEC/celB) [Streptococcus pneumoniae strain Sep6]
ATGTTACAGTGGATTAAGAATTTCTCTATTCCCCTAATTTACCTGAGTTTTCTGTTACTATGGCTTTACTACGCCATTTT
CTCAGTATCCTATTTTGCTTTGTTGGGCTTTGTTTTTCTGCTAGTCTGTCTCTTTTTCCAATTTCCTTGGAAATCTGCTA
GCAAAGTTCTAGTGATTTGTGGAATCTTTGGATTTTGGTTTGTTTTTCAAAATTGGCAACAGAGTCAAGCGAGTCAAAAT
CTGGCGGATTCTGTTGAAGGGGTACGGATTTTGCCTGATACTATTAAGGTTAATGGTGATAGTCTATCCTTTCGTGGCAA
GTCTAACGGTCGTGCTTTCCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACCGACC
TGCATGAGATAGGACTAGAAGGGAAGCTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTAATTACCAAGCCTAT
CTGAAGACTCAGGGAATTTACCAGACTCTCAATATCAAAACAATCCAGTCACTTCAAAAGATTGGCAGTTGGGATATAGG
AGAAAACTTGTCCAGTTTACGTCGAAAGGCTGTGGTTTGGATTAAGACGCACTTTCCAGACCCTATGCGCAATTACATGA
CAGGACTCTTGCTGGGACATCTGGACACCGACTTTGAGGAGATGAATGAGCTTTATTCCAGTCTAGGAATTATCCACCTC
TTTGCCCTATCTGGCATGCAGGTAGGTTTTTTCATGAATGGATTTAAGAAACTTCTCTTGCGATTGGGCTTGACCCAAGA
AAAGTTGAAATGGCTGACTTATCCCTTTTCCCTTATCTATGCGGGACTAACTGGATTTTCAGCATCGGTTATTCGCAGTC
TCTTGCAAAAGCTACTGGCTCAACATGGGGTTAAGGGCTTGGATAATTTTGCCTTGACGGTGCTTGTCCTCTTTATTGTC
ATGCCAAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGCGCTTATGCTTTTATCCTGACCATGACCAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTGCTAGTGAAAGTCTAGTCATCTCCTTGGGCATATTGCCCATTCTATCCTTCTATTTTGCGG
AATTTCAACCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTATTTGACTTGACCTTCTTACCGCTCTTGTCTATT
TTATTTGTCCTTTCCTTTCTCTATCCAGTCATTCAGCTGAACTTTATCTTTGAATGGTTAGAGGGCATTATTCGCTTGGT
CTCGCAGGTGGCAAGGAGACCGCTTGTCTTTGGTCAACCCAACGCATGGCTTTTAATCTTATTGTTAATTTCCTTGGCTT
TGGTCTATGATTTGAGGAAAAACATTAAAGGATTAACAGTATTGAGTTTATTGATTACAGGTCTCTTTTTCCTTACCAAG
TATCCACTGGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTACGGGATGTAACTGGGAAAAC
CATTCTCATAGATGTAGGTGGTAAGGCAGAATCTTATAAGAAAATCGAAAAATGGCAAGAAAAGATGACGACCAGCAATG
CACAGAGAAGCTTGATACCCTATCTTAAAAGTCGAGGAGTAGCTAAGATTGACCAGCTGATTTTGACAAATACGGACAAG
GAACATGTCGGAGATTTGTTAGAGGTGACCAAGGCTTTCCATGTAGGGGAGATTTTAGTATCAAAAGGCAGTTTGAAGCA
GAAGCAATTTGTGGTAGAACTACAGGCGACTCAAACAAAGGTGCGTAGTATGACAGTAGGGGAGAACTTGCCCATTTTTG
GAAGTCAGTTAGAAGTTCTATCTCTAAGGAAAATGGGAGATGGAGGACACGATGATACCCTAGTTTTGTATGGGAAATTC
TTGGATAAGCAATTTCTCTTCACGGGAAATTTGGAGGAGAAAGGAGAGAAGGACTTGCTGAAGCACTATCCAGACTTGAA
AGTAAATGTTTTGAAAGCTAGCCAACATGGCAATAAAAAATCATCAAGTCCAACCTTTCTAGAAAAACTCAAACCAGAGC
TTACTCTTATCTCAGTTGGAAAGAGCAATCGAATGAAACTCCCCCATCAGGAAACATTGACACGACTGGAAGGTATCAAT
AGCAAAGTTTATCGAACTGACCAGCAAGGAGCTATACGTTTTAAGGGGTTGGATAGTTGGAAAATCGAAAGTGTTCGATA
G

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (29-176)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-693)

• Competence protein (Competence) (216-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus pneumoniae TIGR4	97.453	100	0.975
comEC/celB	Streptococcus pneumoniae Rx1	96.113	100	0.961
comEC/celB	Streptococcus pneumoniae D39	96.113	100	0.961
comEC/celB	Streptococcus pneumoniae R6	96.113	100	0.961
comEC/celB	Streptococcus mitis SK321	92.091	100	0.921
comEC/celB	Streptococcus mitis NCTC 12261	91.678	99.866	0.916
comEC	Lactococcus lactis subsp. cremoris KW2	44.534	99.33	0.442