Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   EN71_RS01095 Genome accession   NZ_CP007631
Coordinates   189123..189452 (+) Length   109 a.a.
NCBI ID   WP_000793380.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain NGBS061     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 184123..194452
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EN71_RS01085 (EN72_01105) - 186680..187045 (+) 366 WP_000285373.1 DUF1033 family protein -
  EN71_RS11255 (EN72_01110) comGA 187218..188189 (+) 972 WP_000250805.1 competence type IV pilus ATPase ComGA Machinery gene
  EN71_RS01090 (EN72_01115) comGB 188083..189126 (+) 1044 WP_223295889.1 competence type IV pilus assembly protein ComGB Machinery gene
  EN71_RS01095 (EN72_01120) comGC/cglC 189123..189452 (+) 330 WP_000793380.1 competence type IV pilus major pilin ComGC Machinery gene
  EN71_RS11820 - 189427..189537 (+) 111 Protein_164 competence protein -
  EN71_RS01110 (EN72_01135) comGD 190384..190701 (+) 318 Protein_166 competence type IV pilus minor pilin ComGD -
  EN71_RS01115 (EN72_01140) comGE 190673..190972 (+) 300 WP_000234804.1 competence type IV pilus minor pilin ComGE Machinery gene
  EN71_RS01120 (EN72_01145) comGF 190926..191387 (+) 462 WP_001878820.1 competence type IV pilus minor pilin ComGF Machinery gene
  EN71_RS01125 (EN72_01150) comGG 191365..191736 (+) 372 WP_000601104.1 competence type IV pilus minor pilin ComGG Machinery gene
  EN71_RS01130 (EN72_01155) comGH 191851..192825 (+) 975 WP_001008574.1 class I SAM-dependent methyltransferase Machinery gene
  EN71_RS01135 (EN72_01160) - 192857..194050 (+) 1194 WP_000047534.1 acetate kinase -
  EN71_RS01140 (EN72_01165) - 194202..194408 (+) 207 WP_000798241.1 helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 109 a.a.        Molecular weight: 12129.27 Da        Isoelectric Point: 10.0311

>NTDB_id=106547 EN71_RS01095 WP_000793380.1 189123..189452(+) (comGC/cglC) [Streptococcus agalactiae strain NGBS061]
MKNLLLKCKDKKVKAFTLLEMLVVLIIISVLLLLFVPNLSKQKESVTRTGNAAVVKVVESQAELFELQETGRKASLSTLK
SGGYITEKQEKAYLDYYKDSSNGSQKISS

Nucleotide


Download         Length: 330 bp        

>NTDB_id=106547 EN71_RS01095 WP_000793380.1 189123..189452(+) (comGC/cglC) [Streptococcus agalactiae strain NGBS061]
ATGAAAAATTTATTGTTAAAATGTAAGGATAAGAAGGTTAAAGCATTTACACTTTTAGAAATGTTAGTTGTTTTGATCAT
TATTTCGGTCTTGTTGTTATTGTTTGTACCCAATTTATCAAAACAAAAGGAAAGTGTCACAAGAACTGGAAATGCCGCTG
TTGTCAAGGTTGTAGAAAGTCAAGCCGAACTTTTTGAACTGCAAGAAACAGGTAGAAAAGCTAGTTTATCCACTCTAAAA
TCTGGAGGATATATTACTGAAAAGCAAGAAAAAGCCTATTTAGATTATTATAAAGACAGTTCCAATGGTTCTCAGAAAAT
TTCAAGTTAA

Domains

Predicted by InterProScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis NCTC 12261

60.55

100

0.606
  comGC/cglC Streptococcus mitis SK321

59.633

100

0.596
  comGC Streptococcus gordonii str. Challis substr. CH1

61.165

94.495

0.578
  comGC/cglC Streptococcus pneumoniae TIGR4

57.798

100

0.578
  comGC/cglC Streptococcus pneumoniae R6

57.798

100

0.578
  comGC/cglC Streptococcus pneumoniae Rx1

57.798

100

0.578
  comGC/cglC Streptococcus pneumoniae D39

57.798

100

0.578
  comGC Streptococcus mutans UA159

55.238

96.33

0.532
  comGC Streptococcus mutans UA140

55.238

96.33

0.532
  comGC Lactococcus lactis subsp. cremoris KW2

63.043

84.404

0.532
  comGC Streptococcus suis isolate S10

65.854

75.229

0.495

Multiple sequence alignment