Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   ACGTJS_RS07355 Genome accession   NZ_CP171363
Coordinates   1501077..1502300 (+) Length   407 a.a.
NCBI ID   WP_315040990.1    Uniprot ID   -
Organism   Faucicola mancuniensis strain GVCNT2     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1496077..1507300
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACGTJS_RS07330 (ACGTJS_07330) - 1496260..1497054 (+) 795 WP_315044192.1 acetyl-CoA carboxylase carboxyltransferase subunit alpha -
  ACGTJS_RS07335 (ACGTJS_07335) - 1497079..1497570 (-) 492 WP_410471604.1 GNAT family N-acetyltransferase -
  ACGTJS_RS07340 (ACGTJS_07340) - 1497579..1497872 (-) 294 WP_315044197.1 DUF1778 domain-containing protein -
  ACGTJS_RS07345 (ACGTJS_07345) tilS 1497946..1499175 (+) 1230 WP_410471605.1 tRNA lysidine(34) synthetase TilS -
  ACGTJS_RS07350 (ACGTJS_07350) pilB 1499318..1501021 (+) 1704 WP_410471606.1 type IV-A pilus assembly ATPase PilB Machinery gene
  ACGTJS_RS07355 (ACGTJS_07355) pilC 1501077..1502300 (+) 1224 WP_315040990.1 type II secretion system F family protein Machinery gene
  ACGTJS_RS07360 (ACGTJS_07360) pilD 1502300..1503211 (+) 912 WP_315040991.1 A24 family peptidase Machinery gene
  ACGTJS_RS07365 (ACGTJS_07365) coaE 1503250..1503867 (+) 618 WP_315040992.1 dephospho-CoA kinase -
  ACGTJS_RS07385 (ACGTJS_07385) tpiA 1504403..1505209 (+) 807 WP_315040993.1 triose-phosphate isomerase -
  ACGTJS_RS07390 (ACGTJS_07390) secG 1505240..1505545 (+) 306 WP_315040994.1 preprotein translocase subunit SecG -
  ACGTJS_RS07400 (ACGTJS_07400) - 1505832..1506842 (-) 1011 WP_315040997.1 polyprenyl synthetase family protein -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 44761.65 Da        Isoelectric Point: 9.7514

>NTDB_id=1060918 ACGTJS_RS07355 WP_315040990.1 1501077..1502300(+) (pilC) [Faucicola mancuniensis strain GVCNT2]
MAKAQTEMLMDFVYEGTNRRGEKVKGEATSRSIELARAQLLKQGIQIRSIRKKPKPLFKAGKAIKAIDIAIFVRQLATMM
KAGVPLTQSFEIVADALENPNMKDLVLKLKADIEGGSNFASALRKHPRYFDDLFCSLVEAGEQSGALETMLERVATYKEK
SELLKAKIKKAMKYPIAVIVVAFVVTAILLVKVVPVFSGLFSSFGAELPAFTQMVVNMSEWMKKYWWVVLFSVGGAVVSF
SEAKKRSKAFRDFLDRLSLKLPIFGNIVYQAIIARFARTLSTTFAAGVPLIDALDSTAGATNNVVYYNATQKIKEDVSTG
QQLQFAMRSTNLFPSMAIQMVGIGEEAGSLEEMLDKVATYYENEVDNAVDGLTSLMEPMIMAFLGVVIGGLVVAMYLPIF
QMGSVVG

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=1060918 ACGTJS_RS07355 WP_315040990.1 1501077..1502300(+) (pilC) [Faucicola mancuniensis strain GVCNT2]
ATGGCAAAAGCACAAACTGAAATGTTGATGGACTTTGTCTATGAAGGCACTAATCGTCGTGGCGAAAAGGTAAAAGGTGA
AGCAACCAGCCGTAGCATAGAGTTAGCCCGTGCTCAGTTGTTAAAGCAAGGCATTCAAATTAGAAGTATTCGCAAAAAAC
CAAAGCCATTATTTAAAGCAGGTAAAGCAATTAAAGCGATTGATATTGCAATTTTTGTGCGTCAGTTAGCAACCATGATG
AAAGCGGGTGTGCCTTTAACCCAATCGTTTGAAATTGTTGCTGATGCTTTAGAAAATCCCAATATGAAAGACTTGGTATT
AAAATTAAAAGCAGACATTGAAGGCGGTAGTAACTTTGCCAGTGCATTACGTAAGCACCCACGTTATTTTGATGATTTGT
TTTGCTCGTTAGTCGAAGCAGGTGAACAGTCTGGTGCGCTAGAAACCATGCTTGAGCGTGTGGCAACCTATAAAGAAAAA
AGTGAACTGCTAAAAGCAAAAATCAAAAAGGCAATGAAATATCCAATTGCGGTAATTGTAGTGGCTTTTGTTGTAACGGC
AATTTTATTGGTAAAAGTTGTACCTGTTTTTTCAGGATTATTTAGTTCATTTGGTGCTGAATTACCAGCCTTTACTCAAA
TGGTTGTCAATATGTCAGAATGGATGAAAAAGTATTGGTGGGTTGTTCTGTTCTCCGTTGGTGGTGCAGTAGTTAGTTTT
TCAGAAGCCAAAAAACGCAGCAAAGCTTTTCGAGATTTTTTAGATAGATTGTCATTAAAACTACCAATTTTTGGCAATAT
TGTTTATCAGGCGATTATTGCACGTTTTGCAAGAACGCTTTCAACTACCTTTGCAGCGGGTGTACCATTGATTGACGCAT
TAGATTCAACTGCTGGTGCAACCAACAATGTGGTTTATTATAATGCCACTCAAAAAATCAAAGAAGATGTCTCTACAGGA
CAACAATTACAATTTGCCATGCGTTCAACCAATCTATTTCCCAGTATGGCTATTCAGATGGTTGGCATTGGTGAGGAAGC
AGGTAGTTTAGAAGAGATGCTAGACAAAGTTGCAACCTATTATGAAAATGAAGTGGATAATGCAGTTGATGGTTTAACCA
GTTTGATGGAACCCATGATTATGGCATTTTTGGGTGTTGTTATTGGTGGCTTGGTTGTGGCGATGTACTTACCAATTTTC
CAAATGGGCTCGGTGGTTGGCTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(72-195)

Type II secretion system (T2SS), protein F (T2SSF)

(276-398)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Acinetobacter baumannii D1279779

69.363

100

0.695
  pilC Acinetobacter baylyi ADP1

68.627

100

0.688
  pilC Pseudomonas stutzeri DSM 10701

64.304

97.052

0.624
  pilC Legionella pneumophila strain ERS1305867

56.642

98.034

0.555
  pilG Neisseria gonorrhoeae MS11

45.363

98.034

0.445
  pilG Neisseria meningitidis 44/76-A

45.363

98.034

0.445
  pilC Vibrio cholerae strain A1552

43.137

100

0.432
  pilC Vibrio campbellii strain DS40M4

41

98.28

0.403

Multiple sequence alignment