Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   LMH68_RS10705 Genome accession   NZ_CP170175
Coordinates   2284964..2286193 (-) Length   409 a.a.
NCBI ID   WP_017065898.1    Uniprot ID   A0A4U2BWY9
Organism   Vibrio sp. F13 strain 10N.222.55.B3     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2279964..2291193
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LMH68_RS10665 (LMH68_010665) rpsP 2280045..2280293 (+) 249 WP_004410028.1 30S ribosomal protein S16 -
  LMH68_RS10670 (LMH68_010670) rimM 2280318..2280872 (+) 555 WP_017063236.1 ribosome maturation factor RimM -
  LMH68_RS10675 (LMH68_010675) trmD 2280899..2281639 (+) 741 WP_017061056.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  LMH68_RS10680 (LMH68_010680) rplS 2281699..2282052 (+) 354 WP_004735514.1 50S ribosomal protein L19 -
  LMH68_RS10685 (LMH68_010685) yacG 2282364..2282561 (-) 198 WP_004735515.1 DNA gyrase inhibitor YacG -
  LMH68_RS10690 (LMH68_010690) zapD 2282643..2283383 (-) 741 WP_017063237.1 cell division protein ZapD -
  LMH68_RS10695 (LMH68_010695) coaE 2283410..2284024 (-) 615 WP_229647627.1 dephospho-CoA kinase -
  LMH68_RS10700 (LMH68_010700) pilD 2284027..2284896 (-) 870 WP_229647628.1 prepilin peptidase Machinery gene
  LMH68_RS10705 (LMH68_010705) pilC 2284964..2286193 (-) 1230 WP_017065898.1 type II secretion system F family protein Machinery gene
  LMH68_RS10710 (LMH68_010710) pilB 2286209..2287894 (-) 1686 WP_229647629.1 type IV-A pilus assembly ATPase PilB Machinery gene
  LMH68_RS10715 (LMH68_010715) - 2287901..2288356 (-) 456 WP_229647630.1 pilin -
  LMH68_RS10720 (LMH68_010720) nadC 2288610..2289500 (-) 891 WP_017065901.1 carboxylating nicotinate-nucleotide diphosphorylase -
  LMH68_RS10725 (LMH68_010725) ampD 2289584..2290183 (+) 600 WP_229647631.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45187.27 Da        Isoelectric Point: 10.1190

>NTDB_id=1055454 LMH68_RS10705 WP_017065898.1 2284964..2286193(-) (pilC) [Vibrio sp. F13 strain 10N.222.55.B3]
MSSKSKQSQLKSYHWKGINSSGKKVSGQTLALTELEVREKLKEQHIQIKKIKKKSISAVTRLTHRVKAKDITILTRQLAT
MLATGVPIVQAIKLVSDNHRKAEMKSILSHICKGVEAGTPISKAMRTASRHFDDLYTDLVATGELSGNLAQVFERLATYR
EKSEQLKSKVIKALIYPAMVVAVALTVSYLMLTMVIPEFESMFSGFGADLPWFTQQVLYLSHWMQAYSFYTAVGIGLVVL
IIYQLCQRSHSIKLSVSRLGLRFPVLGGVLAKASIAKFSRTLSTSFSSGIPILMSLKTTAKTAGNLHYESAIIEVHRETA
AGMPMYIAMRNTNAFPEMVLQMVMIGEESGNLDDMLNKVASIYEFEVDNTVDNLGKILEPLIIVFLGTVVGGLVVAMYLP
IFNLMSVLG

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=1055454 LMH68_RS10705 WP_017065898.1 2284964..2286193(-) (pilC) [Vibrio sp. F13 strain 10N.222.55.B3]
ATGAGTAGCAAGTCCAAACAATCACAATTAAAAAGCTATCACTGGAAAGGCATTAACAGCTCAGGCAAGAAAGTGTCTGG
GCAAACGTTAGCGCTCACCGAATTGGAAGTACGAGAAAAGCTCAAAGAACAGCATATTCAGATTAAGAAAATCAAAAAGA
AAAGTATTTCAGCCGTCACTCGTTTAACACATCGCGTCAAAGCCAAAGACATCACAATTTTAACTCGGCAACTTGCGACG
ATGCTGGCTACTGGTGTGCCTATCGTACAAGCGATAAAGTTGGTATCAGACAATCACCGTAAAGCAGAAATGAAATCAAT
TTTATCGCACATCTGCAAAGGTGTAGAAGCCGGCACTCCTATTTCAAAAGCGATGCGAACCGCAAGCCGCCACTTTGATG
ATCTGTATACCGACTTGGTCGCGACAGGCGAACTCTCCGGCAACCTTGCACAAGTATTTGAACGCTTGGCGACCTATCGT
GAAAAGAGTGAGCAACTAAAATCCAAGGTTATAAAAGCTCTCATCTACCCAGCAATGGTTGTAGCGGTCGCCCTTACCGT
TTCCTACTTAATGCTGACCATGGTCATTCCTGAATTTGAATCGATGTTTTCTGGTTTCGGAGCAGACTTACCTTGGTTCA
CCCAGCAAGTGCTTTATCTTTCCCATTGGATGCAGGCCTACAGCTTTTATACTGCCGTAGGCATAGGGCTTGTTGTCCTG
ATTATTTACCAACTGTGTCAGCGTTCCCACTCGATCAAACTGTCTGTTAGTCGGCTAGGATTACGCTTTCCTGTTCTTGG
TGGCGTATTAGCCAAAGCCTCTATTGCCAAATTCAGCCGAACCTTATCAACCAGCTTTAGTTCTGGCATTCCGATTTTAA
TGAGCCTTAAAACCACAGCCAAAACCGCAGGCAACCTGCATTATGAATCGGCCATCATTGAGGTTCACCGAGAAACGGCT
GCTGGCATGCCGATGTACATTGCAATGCGCAATACCAATGCCTTCCCAGAGATGGTTTTGCAGATGGTGATGATTGGTGA
AGAATCAGGAAATCTTGATGATATGCTCAATAAAGTCGCCTCCATTTACGAGTTCGAAGTAGACAACACCGTCGATAATC
TGGGCAAGATCTTAGAGCCATTGATCATCGTGTTTTTAGGAACGGTTGTTGGAGGGCTTGTGGTTGCGATGTACTTACCG
ATCTTTAATCTTATGAGTGTGTTAGGATAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(75-197)

Type II secretion system (T2SS), protein F (T2SSF)

(278-400)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4U2BWY9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Vibrio cholerae strain A1552

79.75

97.8

0.78
  pilC Vibrio campbellii strain DS40M4

73.529

99.756

0.733
  pilC Legionella pneumophila strain ERS1305867

42.569

97.066

0.413
  pilC Acinetobacter baylyi ADP1

41.32

100

0.413
  pilC Acinetobacter baumannii D1279779

41.584

98.778

0.411
  pilC Pseudomonas stutzeri DSM 10701

40.404

96.822

0.391
  pilG Neisseria gonorrhoeae MS11

40.1

97.555

0.391
  pilG Neisseria meningitidis 44/76-A

39.85

97.555

0.389

Multiple sequence alignment