Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   ACEUKD_RS12260 Genome accession   NZ_CP169050
Coordinates   2648652..2649875 (+) Length   407 a.a.
NCBI ID   WP_017635918.1    Uniprot ID   A0AAW9BMM9
Organism   Vibrio diabolicus strain SF42     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2643652..2654875
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACEUKD_RS12240 (ACEUKD_12240) ampD 2644717..2645268 (-) 552 WP_046875077.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  ACEUKD_RS12245 (ACEUKD_12245) nadC 2645361..2646248 (+) 888 WP_005379983.1 carboxylating nicotinate-nucleotide diphosphorylase -
  ACEUKD_RS12250 (ACEUKD_12250) pilA 2646512..2646934 (+) 423 WP_256950981.1 pilin Machinery gene
  ACEUKD_RS12255 (ACEUKD_12255) pilB 2646943..2648628 (+) 1686 WP_374092621.1 type IV-A pilus assembly ATPase PilB Machinery gene
  ACEUKD_RS12260 (ACEUKD_12260) pilC 2648652..2649875 (+) 1224 WP_017635918.1 type II secretion system F family protein Machinery gene
  ACEUKD_RS12265 (ACEUKD_12265) pilD 2649940..2650809 (+) 870 WP_012841418.1 A24 family peptidase Machinery gene
  ACEUKD_RS12270 (ACEUKD_12270) coaE 2650810..2651424 (+) 615 WP_047008979.1 dephospho-CoA kinase -
  ACEUKD_RS12275 (ACEUKD_12275) zapD 2651452..2652192 (+) 741 WP_012841416.1 cell division protein ZapD -
  ACEUKD_RS12280 (ACEUKD_12280) yacG 2652351..2652545 (+) 195 WP_005396692.1 DNA gyrase inhibitor YacG -
  ACEUKD_RS12285 (ACEUKD_12285) rplS 2653041..2653394 (-) 354 WP_005379971.1 50S ribosomal protein L19 -
  ACEUKD_RS12290 (ACEUKD_12290) trmD 2653436..2654197 (-) 762 WP_005396693.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  ACEUKD_RS12295 (ACEUKD_12295) rimM 2654225..2654773 (-) 549 WP_005379964.1 ribosome maturation factor RimM -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 45313.50 Da        Isoelectric Point: 10.3992

>NTDB_id=1049551 ACEUKD_RS12260 WP_017635918.1 2648652..2649875(+) (pilC) [Vibrio diabolicus strain SF42]
MKSTTPQLKNFRWKGINSSGKKTSGQTLAMTEIEVRERLDAQHIKIKKLKKSSISFLTKLSHRVKGRDITVFTRQISTML
ITGVPLVQALKLVSENHKKAEMKSILMSVTRAVEAGTPMSKAMRTASEHFDPLYTDLIATGEQSGNLAEVFERLATYREK
NEQLRAKVIKALIYPAMVVLVALGVSFIMLTKVIPEFEKMFVGFGADLPWFTRQVLDLSAWTQNWSPFIALGSISLFISA
RILSKRSDSFRLMLNRSVLKFPVLGPVLSKAAIAKFSRTLATSFTAGIPILTSLKTTSKTSGNLHYQLAIEEVYRDTAAG
MPMYVAMRNCNVFPELVLQMVMIGEESGRLDDMLNKVATIYEFEVDNTVDNLSKILEPLIIVFLGIVVGGLVTAMYLPIF
NLMSVLG

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=1049551 ACEUKD_RS12260 WP_017635918.1 2648652..2649875(+) (pilC) [Vibrio diabolicus strain SF42]
ATGAAAAGCACTACACCACAACTTAAAAACTTCCGCTGGAAAGGCATCAACAGTTCAGGCAAAAAGACGTCTGGACAAAC
CCTCGCGATGACAGAAATTGAAGTACGCGAGCGTCTAGACGCACAGCACATCAAGATCAAGAAGTTAAAGAAAAGCAGTA
TCTCGTTTCTCACTAAACTCAGCCATCGCGTAAAAGGCAGAGACATCACGGTGTTTACCCGTCAAATTTCGACGATGTTG
ATAACCGGTGTACCCTTAGTTCAGGCTTTAAAATTGGTCTCAGAAAACCATAAAAAAGCAGAGATGAAATCCATTTTGAT
GAGCGTGACACGCGCCGTTGAGGCAGGTACACCCATGTCAAAAGCCATGCGCACTGCAAGTGAACACTTTGACCCACTCT
ATACCGACCTTATCGCAACAGGTGAGCAATCCGGTAACTTAGCGGAAGTGTTCGAGCGCTTAGCCACCTACCGAGAAAAA
AATGAGCAGCTTCGTGCGAAAGTGATAAAAGCACTGATTTACCCAGCCATGGTAGTGCTAGTAGCGTTAGGCGTGTCGTT
TATCATGCTCACCAAAGTCATTCCCGAGTTTGAAAAAATGTTTGTTGGTTTTGGTGCTGACTTACCGTGGTTTACCAGGC
AAGTGTTAGATCTTTCCGCCTGGACACAAAACTGGAGCCCATTTATAGCACTAGGCTCTATCAGTCTATTCATCTCGGCG
AGAATCCTCTCTAAGCGTTCAGATTCTTTTCGCTTAATGCTCAATCGCTCTGTGCTTAAATTTCCTGTTCTTGGCCCTGT
ATTATCAAAAGCCGCTATCGCCAAATTTAGTCGAACACTCGCCACAAGCTTTACAGCGGGCATTCCAATTCTAACCAGTT
TAAAAACCACATCAAAAACATCAGGAAACTTGCACTATCAACTCGCCATAGAAGAAGTCTACCGTGATACCGCCGCAGGT
ATGCCAATGTATGTTGCCATGCGTAACTGTAATGTGTTCCCTGAATTAGTGTTACAAATGGTCATGATCGGTGAAGAGTC
TGGTCGACTTGACGATATGCTCAATAAAGTTGCAACGATCTACGAGTTTGAAGTCGATAACACCGTCGACAACCTTAGTA
AAATTCTAGAGCCGCTAATTATCGTTTTTTTAGGCATCGTTGTTGGCGGATTAGTGACAGCAATGTACTTGCCAATCTTT
AACTTAATGAGTGTATTGGGCTAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(72-195)

Type II secretion system (T2SS), protein F (T2SSF)

(276-398)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Vibrio campbellii strain DS40M4

87.224

100

0.872
  pilC Vibrio cholerae strain A1552

73.775

100

0.74
  pilC Acinetobacter baylyi ADP1

43

98.28

0.423
  pilC Acinetobacter baumannii D1279779

41.439

99.017

0.41
  pilG Neisseria gonorrhoeae MS11

40.494

99.509

0.403
  pilC Legionella pneumophila strain ERS1305867

40.295

100

0.403
  pilG Neisseria meningitidis 44/76-A

40.247

99.509

0.4
  pilC Pseudomonas stutzeri DSM 10701

40.909

97.297

0.398

Multiple sequence alignment