Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ACD269_RS09290 Genome accession   NZ_CP168260
Coordinates   1801919..1803175 (-) Length   418 a.a.
NCBI ID   WP_050118943.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain FC2     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1796919..1808175
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACD269_RS09270 (ACD269_09270) - 1797182..1797343 (-) 162 WP_001055999.1 helix-turn-helix domain-containing protein -
  ACD269_RS09275 (ACD269_09275) lytA 1797689..1798645 (-) 957 WP_373380536.1 N-acetylmuramoyl-L-alanine amidase LytA -
  ACD269_RS09280 (ACD269_09280) - 1799021..1800391 (-) 1371 WP_001036270.1 MATE family efflux transporter -
  ACD269_RS09285 (ACD269_09285) recA 1800698..1801864 (-) 1167 WP_001085463.1 recombinase RecA Machinery gene
  ACD269_RS09290 (ACD269_09290) cinA 1801919..1803175 (-) 1257 WP_050118943.1 competence/damage-inducible protein A Machinery gene
  ACD269_RS09295 (ACD269_09295) - 1803260..1804276 (-) 1017 WP_000239278.1 LCP family protein -
  ACD269_RS09300 (ACD269_09300) - 1804284..1804802 (-) 519 WP_000455530.1 GNAT family N-acetyltransferase -
  ACD269_RS09305 (ACD269_09305) tsaE 1804792..1805235 (-) 444 WP_000275588.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  ACD269_RS09310 (ACD269_09310) comM 1805321..1805941 (-) 621 WP_000839908.1 hypothetical protein Regulator
  ACD269_RS09315 (ACD269_09315) - 1806324..1807187 (-) 864 Protein_1823 helix-turn-helix domain-containing protein -
  ACD269_RS09320 (ACD269_09320) - 1807376..1807546 (+) 171 WP_000742180.1 PhrA family quorum-sensing system peptide -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45077.46 Da        Isoelectric Point: 4.6027

>NTDB_id=1043520 ACD269_RS09290 WP_050118943.1 1801919..1803175(-) (cinA) [Streptococcus pneumoniae strain FC2]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQT
LAKFLGKALVFDPQSQEKLDIFFALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQVDPTLAPYAKTGEVTLRLSTKASSQEEANQALDILENQI
LDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQGKTIAAAESLTAGLFQATVANFSGISSIFKGGFVTYSLEEKSRML
DIPAKNLEEHGVVSEFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIGGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=1043520 ACD269_RS09290 WP_050118943.1 1801919..1803175(-) (cinA) [Streptococcus pneumoniae strain FC2]
ATGAAAGCAGAAATCATTGCTGTTGGAACAGAGATTTTGACAGGACAGATTGTCAACACCAATGCCCAGTTTTTGTCGGA
AAAACTAGCTGAGATTGGGGTAGATGTATATTTTCAGACGGCTGTAGGAGACAATGAAGTTCGTCTCTTGTCTTTGCTTG
AGATTGCCAGTCAACGTAGCAGTCTGGTGATTTTGACAGGCGGTTTGGGGCCAACTGAGGACGACCTAACCAAACAAACC
CTAGCTAAATTTTTAGGGAAAGCATTAGTCTTTGATCCTCAGTCTCAGGAGAAGTTGGATATCTTTTTTGCCCTGCGACC
AGACTATGCCCGAACACCGAATAACGAAAGACAAGCTCAAATTGTAGAAGGAGCGATTCCACTGCCAAACGAAACAGGAC
TGGCTGTTGGAGGAAAATTAGAAGTAGACGGAGTGACCTATGTCGTCCTTCCAGGTCCGCCAAGTGAATTGAAACCCATG
GTCTTAAACCAACTTCTACCCAAGTTGATGACAGGGAGCAAGCTGTATTCCCGAGTTCTTCGTTTCTTTGGGATTGGCGA
GAGCCAGCTGGTTACGATTTTGGCTGATTTAATTGATAATCAGGTCGATCCTACCTTGGCCCCTTATGCCAAGACAGGAG
AAGTCACTCTACGTCTGTCAACAAAGGCTAGCAGTCAAGAAGAGGCGAATCAAGCGCTGGATATCTTGGAAAATCAAATC
TTGGACTGCCAGACTTTCGAAGGAATTTCTTTACGAGACTTTTGCTATGGTTATGGGGAAGAAACTAGTTTAGCCAGCAT
TGTGGTAGAAGAACTGAAAAGGCAAGGGAAAACCATCGCGGCTGCAGAGAGTTTGACGGCAGGTCTTTTCCAAGCTACCG
TGGCGAATTTTTCTGGAATTTCAAGTATATTTAAGGGTGGTTTTGTGACCTATAGCTTGGAGGAAAAATCAAGGATGTTG
GATATTCCTGCCAAGAATTTGGAAGAACATGGTGTGGTGTCTGAATTTACAGCTCAGAAGATGGCTGAGCAGGCACGAAG
CAAGACCCAGTCTGATTTTGGAATTAGTTTGACTGGAGTGGCAGGACCAGATAGCCTAGAAGGACACCCAGTTGGGACAG
TCTTCATAGGCTTGGCGCAAGATCAAGGAACTGAGGTTATCAAGGTTAATATTGGAGGCAGAAGCCGAGCAGATGTACGT
CACATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Competence-damaged protein (CinA)

(262-414)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus pneumoniae TIGR4

99.043

100

0.99
  cinA Streptococcus pneumoniae Rx1

98.804

100

0.988
  cinA Streptococcus pneumoniae R6

98.804

100

0.988
  cinA Streptococcus pneumoniae D39

98.565

100

0.986
  cinA Streptococcus mitis SK321

93.541

100

0.935
  cinA Streptococcus mitis NCTC 12261

93.301

100

0.933
  cinA Streptococcus mutans UA159

70.813

100

0.708
  cinA Streptococcus suis isolate S10

54.808

99.522

0.545
  cinA Bacillus subtilis subsp. subtilis str. 168

45.215

100

0.452

Multiple sequence alignment