Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYC   Type   Machinery gene
Locus tag   ACB350_RS00675 Genome accession   NZ_CP166999
Coordinates   107286..107612 (+) Length   108 a.a.
NCBI ID   WP_002986552.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain Isolate 34     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 102286..112612
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACB350_RS00660 (ACB350_00660) - 104917..105282 (+) 366 WP_002986560.1 DUF1033 family protein -
  ACB350_RS00665 (ACB350_00665) comYA 105376..106314 (+) 939 WP_030127399.1 competence type IV pilus ATPase ComGA Machinery gene
  ACB350_RS00670 (ACB350_00670) comYB 106250..107284 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACB350_RS00675 (ACB350_00675) comYC 107286..107612 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  ACB350_RS00680 (ACB350_00680) comGD 107587..108015 (+) 429 WP_030127397.1 competence type IV pilus minor pilin ComGD -
  ACB350_RS00685 (ACB350_00685) comGE 107972..108256 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  ACB350_RS00690 (ACB350_00690) comYF 108249..108683 (+) 435 WP_002986542.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACB350_RS00695 (ACB350_00695) comGG 108667..108993 (+) 327 WP_002986539.1 competence type IV pilus minor pilin ComGG -
  ACB350_RS00700 (ACB350_00700) comYH 109091..110044 (+) 954 WP_030127396.1 class I SAM-dependent methyltransferase Machinery gene
  ACB350_RS00705 (ACB350_00705) - 110103..111299 (+) 1197 WP_011888536.1 acetate kinase -
  ACB350_RS00710 (ACB350_00710) - 111486..111794 (+) 309 WP_030126458.1 hypothetical protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12376.36 Da        Isoelectric Point: 9.8992

>NTDB_id=1036735 ACB350_RS00675 WP_002986552.1 107286..107612(+) (comYC) [Streptococcus pyogenes strain Isolate 34]
MINQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKA
DGSITEKQEKAYQDYYDKHKNEKARLSN

Nucleotide


Download         Length: 327 bp        

>NTDB_id=1036735 ACB350_RS00675 WP_002986552.1 107286..107612(+) (comYC) [Streptococcus pyogenes strain Isolate 34]
ATGATTAATCAATGGAACAACTTACGACACAAGAAGCTAAAAGGATTTACTCTTCTAGAAATGTTATTGGTGATTCTTGT
CATCAGTGTTTTGATGCTATTATTTGTGCCTAATTTAAGCAAGCAAAAAGACAGGGTTACAGAAACAGGTAATGCCGCTG
TTGTTAAATTAGTGGAGAATCAAGCAGAACTATATGAATTATCTCAAGGCTCAAAACCAAGTTTGAGCCAGTTAAAGGCA
GATGGTAGTATCACTGAGAAACAAGAAAAAGCTTATCAAGACTATTATGACAAACATAAAAATGAAAAAGCCCGTCTTAG
CAATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(12-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

56.19

97.222

0.546
  comGC Lactococcus lactis subsp. cremoris KW2

56.863

94.444

0.537
  comGC/cglC Streptococcus mitis SK321

61.957

85.185

0.528
  comGC/cglC Streptococcus pneumoniae R6

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae TIGR4

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae D39

60.87

85.185

0.519
  comGC/cglC Streptococcus mitis NCTC 12261

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae Rx1

60.87

85.185

0.519
  comYC Streptococcus mutans UA140

55.208

88.889

0.491
  comYC Streptococcus mutans UA159

55.208

88.889

0.491
  comYC Streptococcus suis isolate S10

59.259

75

0.444

Multiple sequence alignment