Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   AB6M99_RS04160 Genome accession   NZ_CP163513
Coordinates   876034..876666 (+) Length   210 a.a.
NCBI ID   WP_121834345.1    Uniprot ID   A0A3L9DUP9
Organism   Streptococcus hillyeri strain S23-3001-2     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 871034..881666
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB6M99_RS04130 (AB6M99_04130) smpB 871600..872070 (+) 471 WP_369351199.1 SsrA-binding protein SmpB -
  AB6M99_RS04135 (AB6M99_04135) - 872132..872560 (-) 429 WP_121834341.1 GtrA family protein -
  AB6M99_RS04140 (AB6M99_04140) - 872721..873287 (+) 567 WP_369351116.1 hypothetical protein -
  AB6M99_RS04145 (AB6M99_04145) - 873428..873937 (+) 510 WP_121834343.1 QueT transporter family protein -
  AB6M99_RS04150 (AB6M99_04150) - 873968..874987 (-) 1020 WP_121834537.1 GIY-YIG nuclease family protein -
  AB6M99_RS04155 (AB6M99_04155) - 875056..875796 (+) 741 WP_121834344.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  AB6M99_RS04160 (AB6M99_04160) comEA/celA/cilE 876034..876666 (+) 633 WP_121834345.1 helix-hairpin-helix domain-containing protein Machinery gene
  AB6M99_RS04165 (AB6M99_04165) comEC/celB 876659..878881 (+) 2223 WP_369351117.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  AB6M99_RS04170 (AB6M99_04170) - 879833..880723 (+) 891 WP_369351118.1 S8 family serine peptidase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 22263.26 Da        Isoelectric Point: 4.3919

>NTDB_id=1030286 AB6M99_RS04160 WP_121834345.1 876034..876666(+) (comEA/celA/cilE) [Streptococcus hillyeri strain S23-3001-2]
METIIEKVREHAILSGVGGGLLILVCIIGFLMLKPKEEAPAFPVVEEVTQVVTEKEEESSSAFSQESEKILVDVKGAVVS
EGVYELSLGDRVRDAIELAGGLSPQADKQSVNFAQKLTDEAVVYVAKIGEVEHSAPAVAGDPQAASGKVNINKATAAELT
TVSGIGEKRAQDIIAYREEHGKFSSLDDLTNVSGIGAKTLEKLKSELTID

Nucleotide


Download         Length: 633 bp        

>NTDB_id=1030286 AB6M99_RS04160 WP_121834345.1 876034..876666(+) (comEA/celA/cilE) [Streptococcus hillyeri strain S23-3001-2]
ATGGAAACAATCATTGAAAAGGTAAGAGAACACGCTATTCTCTCTGGTGTGGGTGGAGGCTTGCTCATTTTGGTGTGTAT
CATTGGGTTTCTGATGTTGAAACCAAAGGAGGAAGCGCCAGCCTTTCCAGTCGTAGAAGAAGTCACACAAGTGGTCACAG
AAAAGGAAGAGGAGAGTAGCTCTGCCTTTTCTCAGGAAAGTGAAAAAATCCTTGTCGATGTCAAAGGTGCTGTCGTATCT
GAAGGAGTCTATGAATTGTCGCTGGGAGACCGTGTGCGTGATGCGATTGAACTGGCAGGTGGTCTGTCTCCTCAAGCTGA
TAAGCAGTCGGTCAATTTTGCGCAGAAACTAACTGATGAAGCTGTTGTTTATGTGGCCAAGATTGGCGAAGTTGAACACT
CAGCACCTGCAGTTGCTGGGGACCCACAGGCAGCGTCTGGCAAAGTCAATATCAATAAAGCGACCGCGGCAGAATTAACA
ACTGTCTCTGGTATTGGTGAAAAGAGGGCTCAAGATATTATCGCTTATCGTGAAGAGCACGGGAAATTTTCTAGTCTTGA
TGACTTGACCAATGTTTCTGGTATTGGTGCTAAGACTCTTGAAAAGCTGAAATCGGAGCTGACCATTGATTAG

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(72-125)

Helix-hairpin-helix motif (HHH_3)

(146-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3L9DUP9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis NCTC 12261

48.649

100

0.514
  comEA/celA/cilE Streptococcus mitis SK321

48.198

100

0.51
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

47.748

100

0.505
  comEA/celA/cilE Streptococcus pneumoniae D39

46.847

100

0.495
  comEA/celA/cilE Streptococcus pneumoniae Rx1

46.847

100

0.495
  comEA/celA/cilE Streptococcus pneumoniae R6

46.847

100

0.495
  comEA Lactococcus lactis subsp. cremoris KW2

39.732

100

0.424
  comEA Bacillus subtilis subsp. subtilis str. 168

43.158

90.476

0.39
  comEA Streptococcus thermophilus LMD-9

52.349

70.952

0.371

Multiple sequence alignment