Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   AB6M99_RS04165 Genome accession   NZ_CP163513
Coordinates   876659..878881 (+) Length   740 a.a.
NCBI ID   WP_369351117.1    Uniprot ID   -
Organism   Streptococcus hillyeri strain S23-3001-2     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 871659..883881
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AB6M99_RS04135 (AB6M99_04135) - 872132..872560 (-) 429 WP_121834341.1 GtrA family protein -
  AB6M99_RS04140 (AB6M99_04140) - 872721..873287 (+) 567 WP_369351116.1 hypothetical protein -
  AB6M99_RS04145 (AB6M99_04145) - 873428..873937 (+) 510 WP_121834343.1 QueT transporter family protein -
  AB6M99_RS04150 (AB6M99_04150) - 873968..874987 (-) 1020 WP_121834537.1 GIY-YIG nuclease family protein -
  AB6M99_RS04155 (AB6M99_04155) - 875056..875796 (+) 741 WP_121834344.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  AB6M99_RS04160 (AB6M99_04160) comEA/celA/cilE 876034..876666 (+) 633 WP_121834345.1 helix-hairpin-helix domain-containing protein Machinery gene
  AB6M99_RS04165 (AB6M99_04165) comEC/celB 876659..878881 (+) 2223 WP_369351117.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  AB6M99_RS04170 (AB6M99_04170) - 879833..880723 (+) 891 WP_369351118.1 S8 family serine peptidase -

Sequence

Protein


Download         Length: 740 a.a.        Molecular weight: 83766.50 Da        Isoelectric Point: 9.2185

>NTDB_id=1030287 AB6M99_RS04165 WP_369351117.1 876659..878881(+) (comEC/celB) [Streptococcus hillyeri strain S23-3001-2]
MIRRLPLPAIYLAFLLVWLYFAIVSGEKLALLGLVCLLVCCFRFYPLKKVGQLLLILTLFASYISYQEWLQTIKADSAPQ
TIQRIQVLPDTISVNGDKLSFRGHWDNQTYQAFYKLTSEKEQRFFKTLTQSVVLDIEAELTEPEGQRNFKGFDYSTYLKS
QGIYRLVQIDTIKTVHKAKRLSLFEIIRGWRRKALVHIYDHFPSPMKHYMTGLLFGHLSKEFEEMSDLYSSLGIIHLFAL
SGMQVGFFAGAFRYLFLWLGLRKDWVDWLTVPFSLVYAGMTGFSVSVIRSLIQLNLSSLGFRGLDNFAATVMVMFLIMPN
FLLTTGGVLSFAYSFILAMTDFKEMKHPRLAEMLTINLGILPLLMWYFASFQPLAILLTAVVSIAFDSLILPLLSLIFIC
SPLVRIDFVNFLFVFLEKGLTLIGQFFNRPVIFGSPSLIVLVLVLVCLGLLYDVLRCKKWAIGLSLMVALLFIITKHPIE
NEVTVVDIGQGDSIFLRDMTGKTLLIDVGGKADFAPKEAWRKGKSDANAERTLIPYLKSRGVHQIDQLLLTHTDTDHIGD
MEVVAKAFSIGEIIVSQGSLTVPSFVERLKALHVPVKAMAAGDKISIMGSQLQVLYPATVGNGENNDSLVLYGKLLDKRF
LFTGDLEEGELDLIKRYPNLPVDILKAGHHGSKGSSYPEFLNHIGAEVALVSAGKNNRYKHPHQETLERFKKENMTVYRT
DQQGAIRFHGWQKWQVETVR

Nucleotide


Download         Length: 2223 bp        

>NTDB_id=1030287 AB6M99_RS04165 WP_369351117.1 876659..878881(+) (comEC/celB) [Streptococcus hillyeri strain S23-3001-2]
TTGATTAGGCGCCTCCCTCTTCCAGCTATCTATCTCGCCTTTCTACTGGTGTGGCTTTATTTTGCTATCGTCTCTGGTGA
AAAGCTGGCGCTGTTGGGTTTGGTATGCTTATTGGTATGTTGCTTTCGGTTTTATCCTTTGAAAAAAGTGGGGCAGTTGC
TCCTTATCCTAACTCTCTTTGCTTCATATATCAGTTATCAAGAATGGCTACAGACTATAAAAGCCGATAGCGCTCCGCAG
ACGATTCAGAGGATACAGGTACTTCCAGATACCATTTCTGTAAATGGCGATAAGCTGTCTTTTAGAGGTCATTGGGATAA
TCAGACCTACCAAGCCTTTTACAAACTGACTTCTGAAAAGGAGCAGCGCTTTTTCAAAACATTAACTCAGAGTGTCGTTT
TGGATATAGAGGCTGAATTGACAGAACCAGAGGGACAACGAAATTTCAAAGGATTTGACTACTCGACTTATTTAAAAAGT
CAGGGAATTTATCGCTTAGTACAGATTGATACGATTAAAACAGTTCATAAGGCGAAGCGGTTAAGTTTGTTTGAAATCAT
CAGGGGATGGCGACGAAAGGCTCTGGTGCATATCTATGACCATTTTCCGTCCCCAATGAAACATTACATGACTGGTCTTC
TTTTTGGACATCTTAGTAAGGAATTTGAGGAAATGAGTGATCTCTATAGCAGTCTTGGGATTATTCATCTTTTTGCCTTA
TCTGGTATGCAAGTCGGCTTTTTTGCGGGCGCTTTTCGTTATCTCTTTTTATGGCTGGGACTACGAAAGGACTGGGTTGA
TTGGCTGACGGTTCCTTTTTCGCTAGTCTATGCAGGCATGACAGGTTTTTCAGTTTCTGTTATTCGTAGCCTAATTCAGC
TTAATCTATCTAGCTTAGGATTTAGAGGGCTTGACAATTTTGCGGCTACCGTTATGGTGATGTTTCTCATCATGCCAAAT
TTTTTATTGACCACAGGTGGTGTTCTAAGTTTCGCCTATTCTTTTATTCTAGCCATGACAGATTTTAAGGAAATGAAGCA
CCCGCGCTTAGCTGAGATGCTGACCATTAATCTTGGCATTTTACCGCTATTGATGTGGTATTTTGCCAGTTTTCAACCTC
TCGCCATCTTGCTGACAGCGGTAGTTTCGATTGCTTTTGATAGCTTGATTTTACCCTTGCTGAGCCTAATATTCATCTGC
TCGCCCTTGGTTAGGATTGACTTTGTTAATTTTCTCTTTGTATTTTTGGAAAAAGGGCTGACGCTGATTGGACAGTTTTT
TAACAGACCAGTTATTTTTGGCAGTCCTAGTTTAATTGTCTTAGTGCTCGTCTTAGTCTGTCTAGGCTTGCTGTACGATG
TTCTCCGTTGTAAGAAATGGGCTATAGGACTGAGTCTCATGGTAGCTCTGCTATTTATCATCACCAAACACCCTATTGAA
AATGAAGTGACGGTTGTTGATATTGGTCAGGGGGACAGTATTTTTCTACGCGATATGACTGGGAAGACTTTGCTGATTGA
TGTTGGTGGCAAGGCTGATTTTGCGCCTAAGGAGGCTTGGAGAAAGGGAAAAAGTGATGCCAATGCGGAGCGGACCCTAA
TTCCATATTTGAAAAGCCGTGGGGTTCATCAGATTGATCAGCTTTTATTGACCCATACCGACACAGACCATATTGGAGAT
ATGGAAGTAGTTGCTAAAGCTTTTTCTATTGGAGAAATTATTGTCAGTCAGGGGAGTTTGACTGTTCCTAGTTTTGTGGA
GAGACTGAAAGCCTTACATGTTCCTGTTAAGGCGATGGCTGCTGGTGATAAAATTTCCATCATGGGAAGTCAGCTACAAG
TGCTTTACCCAGCTACCGTTGGAAATGGTGAAAATAATGATTCCTTGGTCTTGTATGGAAAACTCTTGGACAAACGATTT
TTATTTACAGGAGACCTTGAAGAGGGGGAGCTAGACTTGATTAAAAGGTACCCAAACTTACCTGTTGATATTTTAAAAGC
AGGGCACCATGGCTCAAAAGGATCATCCTATCCTGAATTTTTAAACCACATTGGAGCGGAAGTAGCGCTTGTCTCTGCTG
GTAAAAATAACCGGTACAAACACCCTCATCAAGAAACCTTAGAACGATTTAAAAAAGAAAATATGACAGTCTATCGCACA
GACCAACAAGGTGCCATCCGTTTCCACGGTTGGCAGAAGTGGCAAGTCGAGACAGTGAGGTGA

Domains

Predicted by InterproScan.

Competence protein (Competence)

(213-454)

Domain of unknown function (DUF4131) (DUF4131)

(31-172)

Metallo-beta-lactamase superfamily (Lactamase_B)

(489-694)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

54.521

100

0.546
  comEC/celB Streptococcus mitis NCTC 12261

54.251

100

0.543
  comEC/celB Streptococcus pneumoniae TIGR4

53.504

100

0.536
  comEC/celB Streptococcus pneumoniae Rx1

52.965

100

0.531
  comEC/celB Streptococcus pneumoniae D39

52.965

100

0.531
  comEC/celB Streptococcus pneumoniae R6

52.965

100

0.531
  comEC Lactococcus lactis subsp. cremoris KW2

45.794

100

0.464

Multiple sequence alignment