Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   V8F66_RS10130 Genome accession   NZ_CP158484
Coordinates   2179795..2181024 (-) Length   409 a.a.
NCBI ID   WP_350359620.1    Uniprot ID   A0AAU7XVX0
Organism   Vreelandella sp. SM1641     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2174795..2186024
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V8F66_RS10095 (V8F66_10050) - 2174912..2175286 (+) 375 WP_008957328.1 histone-like nucleoid-structuring protein, MvaT/MvaU family -
  V8F66_RS10100 (V8F66_10055) - 2175889..2176176 (-) 288 WP_348646964.1 helix-turn-helix transcriptional regulator -
  V8F66_RS10105 (V8F66_10060) - 2176577..2176936 (+) 360 WP_281662048.1 hypothetical protein -
  V8F66_RS10110 (V8F66_10065) - 2176967..2177854 (-) 888 WP_350359617.1 DNA replication terminus site-binding protein -
  V8F66_RS10115 (V8F66_10070) yacG 2177894..2178127 (-) 234 WP_179915176.1 DNA gyrase inhibitor YacG -
  V8F66_RS10120 (V8F66_10075) coaE 2178161..2178763 (-) 603 WP_350359618.1 dephospho-CoA kinase -
  V8F66_RS10125 (V8F66_10080) pilD 2178873..2179718 (-) 846 WP_350359619.1 A24 family peptidase Machinery gene
  V8F66_RS10130 (V8F66_10085) pilC 2179795..2181024 (-) 1230 WP_350359620.1 type II secretion system F family protein Machinery gene
  V8F66_RS10135 (V8F66_10090) pilB 2181028..2182800 (-) 1773 WP_281662052.1 type IV-A pilus assembly ATPase PilB Machinery gene
  V8F66_RS10140 (V8F66_10095) - 2183115..2183486 (+) 372 WP_281662053.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  V8F66_RS10145 (V8F66_10100) - 2183778..2184227 (+) 450 WP_281662054.1 anti-virulence regulator CigR family protein -
  V8F66_RS10150 (V8F66_10105) - 2184321..2185136 (+) 816 WP_281662055.1 inositol monophosphatase family protein -
  V8F66_RS10160 (V8F66_10115) - 2185513..2185725 (-) 213 WP_281662082.1 hypothetical protein -
  V8F66_RS10165 (V8F66_10120) - 2185664..2185864 (-) 201 WP_281662056.1 hypothetical protein -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 44839.60 Da        Isoelectric Point: 10.3024

>NTDB_id=1011502 V8F66_RS10130 WP_350359620.1 2179795..2181024(-) (pilC) [Vreelandella sp. SM1641]
MANARRKRRPSLQLYRWKWAGKGPQDRALSGETLGRNKAEVTAELAGQSINVKRIRKINSLSGAGTIKPTDVMVFARQMA
TMIRAGIPLLQAFQVVGESLKKPAMAMLVEQMRSDVSSGSSFSDALRRHPKHFDQLFVNLIDAGEQAGALDQMLDRVATY
KEKVESLKARVKKALWYPSAVMIVGISVTLLLLIKVVPQFESMFNNFDAELPALTQMTVNLSELAQRYWLVALGSLVATV
LAIKISVQRSPKMAYGMDVLVLRLPVIGDIMHKSSLARFARTLATTFASGVPLMEGLETASGAVGNKVYERAVIQTRKDV
ATGQQLHFAMRMTNRFPPLAIQMVSIGEESGSLDAMLNRVADYYEEEVDNKVDALTSLMEPIIIVVLGVLVGGVVVSIYL
PIFSLGSAL

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=1011502 V8F66_RS10130 WP_350359620.1 2179795..2181024(-) (pilC) [Vreelandella sp. SM1641]
ATGGCAAACGCTCGGCGTAAGCGTCGCCCATCTCTTCAACTTTATCGTTGGAAATGGGCGGGCAAAGGCCCTCAAGACAG
AGCACTGAGCGGCGAAACCCTTGGCCGTAATAAAGCGGAGGTAACGGCTGAACTAGCGGGGCAAAGCATCAATGTTAAGC
GCATTCGCAAAATAAACAGCCTCAGCGGCGCAGGCACTATTAAGCCTACCGACGTGATGGTGTTTGCGCGCCAAATGGCG
ACCATGATTCGCGCCGGCATTCCTTTGTTACAGGCTTTCCAAGTCGTTGGCGAAAGTCTGAAAAAGCCCGCCATGGCGAT
GTTGGTAGAGCAGATGAGGAGCGATGTTTCATCGGGCTCAAGTTTTTCTGATGCGTTACGCCGTCACCCAAAACATTTTG
ATCAATTGTTTGTTAACCTCATCGATGCTGGCGAACAAGCTGGTGCGCTGGATCAGATGCTGGACCGTGTCGCGACTTAT
AAAGAGAAAGTGGAATCGCTAAAAGCGCGCGTTAAGAAAGCCCTTTGGTACCCTAGCGCCGTGATGATCGTCGGCATATC
GGTCACCCTGCTGCTGCTGATTAAAGTCGTCCCCCAGTTTGAAAGCATGTTTAATAATTTTGATGCGGAGCTTCCTGCCC
TGACTCAAATGACCGTTAACTTATCCGAACTTGCTCAGCGCTATTGGCTTGTGGCCCTGGGTAGCCTGGTGGCCACGGTG
CTAGCCATCAAAATCAGCGTTCAACGCTCACCCAAAATGGCTTATGGCATGGACGTTTTGGTGCTTCGCTTACCGGTGAT
CGGCGACATTATGCATAAATCCTCCCTTGCCCGTTTTGCGCGCACCTTAGCAACGACCTTTGCTTCCGGCGTACCGTTGA
TGGAAGGTTTAGAGACCGCCTCTGGGGCCGTGGGCAATAAAGTTTATGAACGCGCCGTCATACAAACCCGTAAAGATGTC
GCGACCGGGCAGCAGCTACACTTTGCCATGCGCATGACCAACCGCTTTCCTCCCCTGGCAATTCAAATGGTCAGCATCGG
CGAAGAGTCGGGGTCGTTGGATGCCATGTTGAACCGCGTCGCTGATTATTACGAAGAAGAAGTCGACAATAAAGTCGACG
CCCTTACCTCCCTAATGGAGCCGATTATTATCGTCGTATTGGGCGTACTGGTGGGCGGCGTCGTTGTGTCTATATACTTG
CCAATCTTCAGCTTAGGCTCGGCTCTCTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(75-198)

Type II secretion system (T2SS), protein F (T2SSF)

(279-401)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

51.908

96.088

0.499
  pilC Acinetobacter baumannii D1279779

52.219

93.643

0.489
  pilC Legionella pneumophila strain ERS1305867

48.03

99.267

0.477
  pilC Acinetobacter baylyi ADP1

50.914

93.643

0.477
  pilC Vibrio campbellii strain DS40M4

43.103

99.267

0.428
  pilC Vibrio cholerae strain A1552

42.118

99.267

0.418
  pilG Neisseria meningitidis 44/76-A

42.172

96.822

0.408
  pilG Neisseria gonorrhoeae MS11

42.172

96.822

0.408

Multiple sequence alignment