Detailed information of regulator


Summary

Regulator ID REG0349 experimental
Regulator type protein
Regulatory pathway (from literatures) Tpp
KEGG pathway (determined by BlastKOALA) -
Related T6SS T6SS00929 experimental (Type i3)
Strain Serratia marcescens subsp. marcescens Db11
Replicon chromosome
Sequence Protein sequence (581 a.a.); Nucleotide sequence (1743 bp)
Description Deletion of the Fha homolog SMA2267 in S. marcescens abolished Hcp secretion.
Reference
External database links

Locus tag (Gene) SMDB11_2267 (Fha)
Coordinates (Strand) 2388490..2390232 (+)
NCBI ID 560174110
GenBank HG326223
Uniprot ID UPI00032409C0
KEGG ID -
KEGG pathway (determined by BlastKOALA) -
PDB ID -
  Target
Target Regulation (↓/↑) Target sequence
Unknown ↓ -
Pfam domain hit(s) of regulator

Domain Pfam ID E-value Aligned region
FHA PF00498.28 3.8e-07 27..93
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-580 MRFSIVKNKSGQVPPQSSCDFLPPGGTIGRSVDNNLVLPDEERAISRLQAIVHISADGECRITNRGNVTRVLLNDIPLERGRQVELQDGDVLGIDDYQIEVSALHQHAAPQAQPVAKAAAVAAAAAPTAAAKEKSAAPIPNEIWDSLVEEFTPNAPAAVTPPPVANPDSHPLLETPARELNPADPLAQLAGDVDLRQLQQQQTDPAALFNTDTTFEREHILADTTPSALLAEQAAPPRPAPPVQNAQQPEQELDPLALFGGSSAPASPETLNSNDPLGLLMGGAVPLAQPEEPVQPPAPPSPSPAPIAAQPAAPRPQPTPPPMQTPEPQPQPAPQFSQQEPPAQPPRPRQGNRLGIDPVAYQSAQRQHAAAPSGDALEGPLLAALLQGIGLDDLQPQPHFDEQQIRQAGRLLSLFSQGTVALLSSRSILKRGVKAEMTMILDEANNPFKLLPSGKTVLMQMFGSQMPGFMPPEQAVRDALIDLQAHQLGMIAGIRAIIAAMLQSFNPERLEEEARKEGVAPRLSLPANRKAALWDYFVKNYQQTSGEIEDDFHTLFGEAFLHAYDVEVNQYKDSQTKPDA


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9486 - -


  Protein sequence of regulator: 581 a.a.    .

>REG0349 HG326223:2388490-2390232 [Serratia marcescens subsp. marcescens Db11]
MRFSIVKNKSGQVPPQSSCDFLPPGGTIGRSVDNNLVLPDEERAISRLQAIVHISADGECRITNRGNVTRVLLNDIPLER
GRQVELQDGDVLGIDDYQIEVSALHQHAAPQAQPVAKAAAVAAAAAPTAAAKEKSAAPIPNEIWDSLVEEFTPNAPAAVT
PPPVANPDSHPLLETPARELNPADPLAQLAGDVDLRQLQQQQTDPAALFNTDTTFEREHILADTTPSALLAEQAAPPRPA
PPVQNAQQPEQELDPLALFGGSSAPASPETLNSNDPLGLLMGGAVPLAQPEEPVQPPAPPSPSPAPIAAQPAAPRPQPTP
PPMQTPEPQPQPAPQFSQQEPPAQPPRPRQGNRLGIDPVAYQSAQRQHAAAPSGDALEGPLLAALLQGIGLDDLQPQPHF
DEQQIRQAGRLLSLFSQGTVALLSSRSILKRGVKAEMTMILDEANNPFKLLPSGKTVLMQMFGSQMPGFMPPEQAVRDAL
IDLQAHQLGMIAGIRAIIAAMLQSFNPERLEEEARKEGVAPRLSLPANRKAALWDYFVKNYQQTSGEIEDDFHTLFGEAF
LHAYDVEVNQYKDSQTKPDA*

  Nucleotide sequence of regulator: 1743 bp    .

>REG0349 HG326223:2388490-2390232 [Serratia marcescens subsp. marcescens Db11]
ATGCGATTTTCCATTGTAAAAAATAAAAGCGGCCAGGTTCCGCCGCAGAGCAGTTGCGATTTTCTGCCGCCGGGCGGCAC
CATCGGCCGCAGCGTGGACAACAACCTGGTGCTGCCGGACGAAGAGCGCGCCATTTCCCGCCTGCAGGCGATCGTGCACA
TTTCCGCTGACGGCGAATGCCGCATCACCAACCGCGGCAACGTTACCCGCGTGCTGCTGAACGACATTCCGCTGGAACGC
GGCCGCCAGGTTGAACTGCAGGATGGCGACGTACTCGGCATCGACGATTACCAGATTGAAGTCAGCGCGCTGCACCAGCA
CGCCGCGCCACAGGCTCAACCGGTGGCCAAGGCCGCCGCCGTTGCCGCTGCTGCGGCCCCAACAGCCGCCGCCAAAGAAA
AATCTGCTGCGCCAATCCCCAACGAAATCTGGGACAGCCTGGTGGAAGAATTTACGCCGAATGCGCCGGCCGCCGTCACG
CCGCCGCCAGTCGCCAATCCAGACAGCCATCCACTGCTGGAGACCCCCGCTCGCGAGCTGAACCCGGCCGATCCGCTGGC
GCAGCTGGCGGGCGATGTCGATCTGCGCCAATTGCAGCAACAGCAAACCGATCCGGCGGCGCTGTTCAACACCGACACCA
CCTTTGAGCGTGAGCATATCCTGGCCGACACCACCCCCAGCGCGCTGCTGGCGGAGCAGGCTGCGCCACCGCGCCCTGCT
CCCCCCGTCCAGAATGCGCAGCAACCGGAACAAGAGCTGGATCCACTGGCGCTGTTCGGCGGTTCATCCGCGCCCGCTTC
GCCAGAGACGTTAAACAGCAACGATCCGCTGGGGCTGCTGATGGGCGGCGCCGTGCCGCTGGCCCAGCCGGAGGAGCCGG
TACAGCCGCCCGCACCGCCGTCGCCGTCACCGGCGCCGATCGCCGCACAACCGGCGGCGCCGCGCCCACAGCCGACGCCG
CCGCCCATGCAGACGCCTGAGCCACAGCCCCAACCTGCGCCGCAGTTCAGCCAGCAGGAACCGCCTGCACAGCCGCCGCG
CCCGCGCCAGGGCAACCGCCTGGGCATCGATCCAGTTGCCTACCAGTCTGCCCAGCGGCAGCACGCCGCCGCGCCAAGTG
GCGACGCATTGGAAGGGCCGTTGCTGGCGGCGCTGCTGCAAGGCATCGGTCTCGACGATCTGCAACCGCAGCCGCACTTT
GACGAACAACAGATCCGCCAGGCCGGTCGCCTGCTGAGCCTGTTCTCGCAAGGCACCGTCGCCCTGCTCTCATCCCGCTC
GATCCTCAAGCGCGGCGTGAAGGCAGAGATGACCATGATCCTCGACGAAGCCAACAACCCGTTCAAGCTGCTGCCTTCGG
GAAAAACGGTGCTGATGCAGATGTTCGGTAGCCAGATGCCGGGCTTTATGCCGCCGGAACAGGCGGTGCGTGACGCGCTG
ATCGACCTGCAGGCGCACCAGCTGGGGATGATCGCCGGTATTCGCGCCATCATCGCCGCCATGCTGCAGTCGTTCAACCC
GGAGCGCCTCGAAGAGGAAGCGCGCAAGGAAGGCGTGGCGCCGCGTCTGTCGCTGCCCGCCAACCGCAAGGCCGCGCTGT
GGGACTACTTCGTGAAGAACTATCAGCAAACCTCCGGCGAGATCGAGGACGATTTCCACACCCTGTTCGGCGAAGCCTTC
CTGCACGCCTATGACGTTGAAGTGAATCAATACAAAGACTCACAGACCAAACCGGACGCGTAA