Detailed information of regulator


Summary

Regulator ID REG0052 experimental
Regulator type protein
Regulatory pathway (from literatures) Tpp
KEGG pathway (determined by BlastKOALA) -
Related T6SS T6SS00003 experimental (Type i3)
Strain Pseudomonas aeruginosa PAO1
Replicon chromosome
Sequence Protein sequence (571 a.a.); Nucleotide sequence (1713 bp)
Description TagR functions upstream of PpkA and TagR could function independently of PpkA, or it could act in conjunction with the C-terminal domains of the kinase to efficiently recognize and signal in response to H1-T6SS activation cue(s).
Reference
External database links

Locus tag (Gene) PA0071 (tagR)
Coordinates (Strand) 83380..85092 (-)
NCBI ID 15595269
RefSeq NC_002516
Uniprot ID Q9I761_PSEAE
KEGG ID pae:PA0071
KEGG pathway (determined by BlastKOALA) -
PDB ID -
  Target
Target Regulation (↓/↑) Target sequence
PA0074 (PpkA) ↓ 15595272
Pfam domain hit(s) of regulator

Domain Pfam ID E-value Aligned region
FGE-sulfatase PF03781.18 4.5e-30 127..359
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-570 MFEKAILPLALGACLAFAAPAWAEGDSPDNPKPLADDVALPLPCGGEMVFRHVYVLAEGALDDREVNLGYAFNEGEAGYQQSFISGYRRDYVNGQFSLADLAPAWQQKLSASLPKPAAGTPLKPMLYFIGKYEVTARQYAAVMSQAAALSGQGEAPACDVPDGMAARLPKVNLSRFDAERFGAVYSAWLLKNHPELLPVSGRGKNPEDGGIGFVRLPTEVEWEFAARGGQAVSRQELEGRLFPRKVEGSDQEGPLGDWAVYNQVAGGTGQAARLLPVGMKRPNPLGLFDVIGNAAEMVQESFQLVHAGRRQGTYGGFVVKGGNYLEGEMTLFTGMRREYPLFAADGSEQRNETTGFRVAIGALSAPRSRYPELFAQWQKEGRLAALTDAIDDAQDPTKQLDGIIAATRDPQMQAQLAQINEELKRNVSLIARQREEAAGNLIQSAALVAETINNYNIRLTNLKKDREKAVAARDQATAQLYAGAIANGRSALDGALAIYIDNLATGTRYTDAVIQAQFQRIQEELNRNPVLGKSLVKRATLFVKHVGDYRQQHRAEPEAVLKELLASSGR


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
SP(Sec/SPI) 0.9958 pos: 23-24. AWA-EG. MFEKAILPLALGACLAFAAPAWA


  Protein sequence of regulator: 571 a.a.    .

>REG0052 NC_002516:c85092-83380 [Pseudomonas aeruginosa PAO1]
MFEKAILPLALGACLAFAAPAWAEGDSPDNPKPLADDVALPLPCGGEMVFRHVYVLAEGALDDREVNLGYAFNEGEAGYQ
QSFISGYRRDYVNGQFSLADLAPAWQQKLSASLPKPAAGTPLKPMLYFIGKYEVTARQYAAVMSQAAALSGQGEAPACDV
PDGMAARLPKVNLSRFDAERFGAVYSAWLLKNHPELLPVSGRGKNPEDGGIGFVRLPTEVEWEFAARGGQAVSRQELEGR
LFPRKVEGSDQEGPLGDWAVYNQVAGGTGQAARLLPVGMKRPNPLGLFDVIGNAAEMVQESFQLVHAGRRQGTYGGFVVK
GGNYLEGEMTLFTGMRREYPLFAADGSEQRNETTGFRVAIGALSAPRSRYPELFAQWQKEGRLAALTDAIDDAQDPTKQL
DGIIAATRDPQMQAQLAQINEELKRNVSLIARQREEAAGNLIQSAALVAETINNYNIRLTNLKKDREKAVAARDQATAQL
YAGAIANGRSALDGALAIYIDNLATGTRYTDAVIQAQFQRIQEELNRNPVLGKSLVKRATLFVKHVGDYRQQHRAEPEAV
LKELLASSGR*

  Nucleotide sequence of regulator: 1713 bp    .

>REG0052 NC_002516:c85092-83380 [Pseudomonas aeruginosa PAO1]
ATGTTTGAGAAAGCCATTCTTCCGCTCGCCCTCGGCGCCTGCCTGGCATTTGCCGCGCCGGCCTGGGCCGAAGGCGACTC
GCCGGACAATCCCAAGCCGCTGGCCGACGACGTCGCCCTGCCGCTGCCGTGTGGCGGCGAGATGGTCTTCCGGCATGTCT
ACGTACTCGCCGAAGGCGCCCTCGACGATCGCGAGGTCAACCTCGGCTACGCCTTCAACGAAGGCGAGGCGGGCTACCAG
CAGTCGTTCATCTCCGGCTACCGGCGCGACTACGTGAACGGCCAGTTCAGCCTCGCCGACCTGGCACCGGCCTGGCAGCA
GAAGCTCTCCGCCAGCCTGCCGAAGCCTGCCGCCGGCACCCCGCTGAAGCCGATGCTGTACTTCATCGGCAAGTACGAGG
TGACCGCCCGCCAGTACGCCGCGGTGATGAGCCAGGCGGCCGCGCTCTCCGGCCAGGGCGAGGCGCCGGCCTGCGACGTG
CCGGACGGAATGGCCGCGCGGCTGCCCAAGGTCAACCTCTCGCGCTTCGACGCCGAACGCTTCGGCGCGGTGTACAGCGC
CTGGCTGCTGAAGAACCACCCGGAACTGCTGCCGGTCAGCGGCCGCGGCAAGAATCCCGAGGACGGCGGCATCGGCTTCG
TCCGCCTGCCCACCGAGGTCGAGTGGGAGTTCGCCGCGCGCGGCGGCCAGGCGGTAAGCCGCCAGGAACTGGAAGGCCGG
CTGTTCCCGCGCAAGGTCGAGGGCAGCGACCAGGAAGGCCCGCTGGGCGACTGGGCGGTGTACAACCAGGTCGCCGGCGG
CACCGGGCAGGCCGCGCGACTGTTGCCGGTAGGGATGAAGCGGCCGAACCCGCTGGGCCTGTTCGACGTGATCGGCAATG
CCGCGGAGATGGTCCAGGAGTCCTTCCAACTGGTCCACGCCGGTCGCCGGCAGGGCACATATGGCGGTTTCGTGGTGAAG
GGCGGGAACTATCTCGAAGGCGAGATGACTCTATTCACCGGGATGCGCCGCGAATACCCGCTGTTCGCCGCCGACGGCAG
CGAACAGCGCAACGAGACCACCGGTTTCCGTGTCGCCATCGGCGCGCTGTCCGCGCCGCGCTCGCGCTATCCCGAGCTGT
TCGCCCAATGGCAGAAGGAAGGCCGACTAGCGGCATTGACCGATGCCATCGATGACGCTCAAGATCCCACCAAGCAATTG
GACGGAATCATTGCCGCCACCCGCGACCCGCAGATGCAGGCGCAGTTGGCCCAGATAAACGAGGAACTCAAGCGTAACGT
TTCGTTGATCGCCCGGCAGCGCGAAGAGGCCGCCGGAAACCTGATACAGTCGGCGGCACTGGTCGCCGAGACGATCAACA
ACTACAACATACGCCTGACCAACCTCAAGAAGGACAGGGAGAAAGCCGTGGCAGCCAGGGATCAGGCGACCGCCCAGCTC
TATGCCGGCGCCATCGCCAACGGGCGCAGCGCCCTCGATGGCGCATTGGCCATCTACATCGACAACCTCGCCACCGGCAC
CCGTTACACCGACGCGGTGATCCAGGCGCAGTTCCAGCGCATCCAGGAAGAACTCAATCGCAACCCGGTTCTGGGCAAGA
GCCTGGTCAAGCGCGCGACCCTGTTCGTCAAACACGTCGGAGATTATCGCCAGCAGCACCGGGCCGAGCCGGAGGCGGTA
TTGAAGGAATTGCTCGCGTCCAGCGGGCGTTGA