Detailed information of regulator


Summary

Regulator ID REG0042 experimental
Regulator type protein
Regulatory pathway (from literatures) Tpp
KEGG pathway (determined by BlastKOALA) Bacterial secretion system (map03070); Biofilm formation - Pseudomonas aeruginosa (map02025)
Related T6SS T6SS00003 experimental (Type i3)
Strain Pseudomonas aeruginosa PAO1
Replicon chromosome
Sequence Protein sequence (243 a.a.); Nucleotide sequence (729 bp)
Description Once the environmental signal is removed, PppA would reverse Fha-1 phosphorylation process by dephosphorylating p-Fha1.
Reference
External database links

Locus tag (Gene) PA0075 (PppA)
Coordinates (Strand) 90106..90834 (-)
NCBI ID 15595273
RefSeq NC_002516
Uniprot ID Q9I757_PSEAE
KEGG ID pae:PA0075
KEGG pathway (determined by BlastKOALA) map03070; map02025
PDB ID 6JKV
  Target
Target Regulation (↓/↑) Target sequence
PA0081 (Fha-1/TagH) ↑ 15595279
Pfam domain hit(s) of regulator

Domain Pfam ID E-value Aligned region
PP2C_2 PF13672.8 1.7e-11 21..207
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-242 MVPNSVSYYRSASYSHVGMVRKVNEDASLDAPEAGLWVVADGMGGHAAGDFVSSLIVDTLRRIPAASSLPAYVGALRTGLAQVNERVRQEAGLRGVSVMGSTLVLLAARGNQASCLWAGDSRLYRLRGGVLEAISRDHSYVQELLDNALISEEEARHHPRANVVTRAVGVHEQLELSEAALHVLPGDSFLLCSDGLNKTADDSELRDVLSHSDPYAVVRSLVHLGLTRGAPDNITALVVRAF


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9843 - -


  Protein sequence of regulator: 243 a.a.    .

>REG0042 NC_002516:c90834-90106 [Pseudomonas aeruginosa PAO1]
MVPNSVSYYRSASYSHVGMVRKVNEDASLDAPEAGLWVVADGMGGHAAGDFVSSLIVDTLRRIPAASSLPAYVGALRTGL
AQVNERVRQEAGLRGVSVMGSTLVLLAARGNQASCLWAGDSRLYRLRGGVLEAISRDHSYVQELLDNALISEEEARHHPR
ANVVTRAVGVHEQLELSEAALHVLPGDSFLLCSDGLNKTADDSELRDVLSHSDPYAVVRSLVHLGLTRGAPDNITALVVR
AF*

  Nucleotide sequence of regulator: 729 bp    .

>REG0042 NC_002516:c90834-90106 [Pseudomonas aeruginosa PAO1]
ATGGTGCCCAACTCAGTCAGCTACTACAGGTCGGCCAGCTACAGCCACGTCGGCATGGTCCGCAAGGTCAACGAAGACGC
CAGTCTCGACGCCCCCGAGGCGGGACTCTGGGTGGTCGCCGACGGCATGGGCGGCCACGCCGCCGGCGACTTCGTCAGCA
GCCTGATCGTCGATACCCTGCGGCGCATCCCGGCGGCCTCCTCGCTACCGGCCTATGTCGGCGCGTTGCGCACCGGCCTC
GCCCAGGTCAACGAGCGGGTTCGCCAGGAGGCTGGCCTGCGTGGCGTCAGCGTGATGGGCAGCACCCTGGTACTGCTCGC
CGCGCGCGGCAACCAGGCGAGCTGCCTGTGGGCCGGCGACAGCCGCCTGTACCGCCTGCGCGGCGGCGTGCTGGAAGCCA
TCTCGCGGGACCACAGCTACGTCCAGGAGCTGCTCGACAACGCATTGATCAGCGAGGAAGAGGCGCGCCACCATCCGCGC
GCCAACGTGGTCACCCGCGCGGTCGGCGTGCACGAGCAACTGGAACTGTCGGAAGCCGCGCTGCACGTGCTGCCCGGCGA
CAGCTTCCTGCTCTGCAGCGACGGCCTCAACAAGACCGCCGACGACAGCGAACTGCGCGACGTGCTCAGCCACAGCGATC
CCTATGCGGTGGTCCGCAGCCTGGTCCACCTGGGCCTGACCCGCGGCGCCCCGGACAACATCACGGCCCTGGTGGTCAGG
GCCTTCTGA