Detailed information of regulator


Summary

Regulator ID REG0037 experimental
Regulator type protein
Regulatory pathway (from literatures) c-di-GMP regulatory pathway
KEGG pathway (determined by BlastKOALA) Cell cycle - Caulobacter (map04112)
Related T6SS T6SS01211 experimental (Type i1); T6SS01212 experimental (Type i4a); T6SS01213 experimental (Type i3)
Strain Pseudomonas aeruginosa PAK
Replicon chromosome
Sequence Protein sequence (672 a.a.); Nucleotide sequence (2016 bp)
Description The DgcP‐mediated modulation of c‐di‐GMP levels plays a role in the regulation of T6SS‐related genes in both P. aeruginosa PAK and P. savastanoi pv. savastanoi NCPPB 3335.
Reference
External database links

Locus tag (Gene) Y880_05519 (dgcP)
Coordinates (Strand) 5487251..5489266 (-)
NCBI ID 489205065
RefSeq NZ_CP020659
Uniprot ID S0JAX7_PSEAW, DGCP_PSEAE, A0A0C7AR28_PSEAI
KEGG ID pae:PA5487
KEGG pathway (determined by BlastKOALA) map04112
PDB ID -
  Target
Target Regulation (↓/↑) Target sequence
the levels of c-di-GMP ↓ -
Pfam domain hit(s) of regulator

Domain Pfam ID E-value Aligned region
GGDEF PF00990.23 9.7e-47 511..667
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-671 MSRDDVQRWKDKYLENIEQQERLQRRWDARIDLLRRGLVRSSLAAEGSDKAVDQCMKELREILRRDDMDAGLSGLIPRLEKAVLDSEQRRQQRTQQNIDALGELAQQLLALDLPRELRKPLKQFARDIEERARQSREIPILLSELSRLQRQALAERKGGDAEDGRPSLLQRLFGGKESETTAEPSASVPSVVAASNTPIQPAAAAPSLPVAEHDEAPGGPPQPLPARTVAAIESAPAGWVGVAERGEPNQILLDEPREIWLDSLPLPAGLSFSETLEEAGAEPSPAMPADVESAPEAPATPVDNLDGQAVDEAYELPPPIPEPGYSAVAPHIEASLLRLLDGLSLPSSHQPQAEALRERIDGSLNWYELVPVLDDLAVLVLSLADSGQRDFEEYLRQLNERLESFLGHLGDAHAGYTDVLDNARGFDQSLREQVSGLQASVQQATDLNSLKLAVDSRLNGLLASMDEHQREQAEHEQEVSGRLQALMERVNSMEQDAKAFHSHLEDQRQKALTDPLTGLPNRAALSERLEQEVARRHRDGGDLLLAVLDIDHFKRINDDFGHLAGDKVLKIIAGELRKRLRQADFIARFGGEEFVVLLPATSLEAGRQLLERLRAAIAACPFHFKGEPLSITCSAGITAFEGNEAGEAVFERADQALYRAKRAGRDRLEVA


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9729 - -


  Protein sequence of regulator: 672 a.a.    .

>REG0037 NZ_CP020659:c5489266-5487251 [Pseudomonas aeruginosa PAK]
MSRDDVQRWKDKYLENIEQQERLQRRWDARIDLLRRGLVRSSLAAEGSDKAVDQCMKELREILRRDDMDAGLSGLIPRLE
KAVLDSEQRRQQRTQQNIDALGELAQQLLALDLPRELRKPLKQFARDIEERARQSREIPILLSELSRLQRQALAERKGGD
AEDGRPSLLQRLFGGKESETTAEPSASVPSVVAASNTPIQPAAAAPSLPVAEHDEAPGGPPQPLPARTVAAIESAPAGWV
GVAERGEPNQILLDEPREIWLDSLPLPAGLSFSETLEEAGAEPSPAMPADVESAPEAPATPVDNLDGQAVDEAYELPPPI
PEPGYSAVAPHIEASLLRLLDGLSLPSSHQPQAEALRERIDGSLNWYELVPVLDDLAVLVLSLADSGQRDFEEYLRQLNE
RLESFLGHLGDAHAGYTDVLDNARGFDQSLREQVSGLQASVQQATDLNSLKLAVDSRLNGLLASMDEHQREQAEHEQEVS
GRLQALMERVNSMEQDAKAFHSHLEDQRQKALTDPLTGLPNRAALSERLEQEVARRHRDGGDLLLAVLDIDHFKRINDDF
GHLAGDKVLKIIAGELRKRLRQADFIARFGGEEFVVLLPATSLEAGRQLLERLRAAIAACPFHFKGEPLSITCSAGITAF
EGNEAGEAVFERADQALYRAKRAGRDRLEVA*

  Nucleotide sequence of regulator: 2016 bp    .

>REG0037 NZ_CP020659:c5489266-5487251 [Pseudomonas aeruginosa PAK]
ATGAGTCGCGACGACGTCCAGCGCTGGAAAGACAAGTACCTGGAGAACATCGAGCAGCAGGAGCGCCTGCAACGGCGCTG
GGATGCCCGGATCGACCTGCTGCGTCGCGGCCTGGTGCGTAGCAGTCTGGCGGCCGAAGGCAGCGACAAGGCGGTCGACC
AGTGCATGAAGGAGCTGCGCGAGATCCTCCGTCGCGACGACATGGACGCCGGCCTGTCGGGCCTGATTCCGCGCCTGGAA
AAGGCCGTGCTCGACTCCGAACAGCGCCGCCAGCAACGCACCCAGCAGAACATCGATGCCCTCGGCGAACTGGCCCAGCA
GTTGCTGGCCCTGGACCTGCCGCGGGAACTGCGCAAGCCGCTGAAGCAGTTCGCCCGCGATATCGAGGAGCGCGCCCGGC
AGTCGCGCGAGATTCCGATCCTGCTCAGCGAGCTGAGCAGGCTGCAACGCCAGGCGCTGGCCGAGCGCAAGGGCGGCGAT
GCCGAAGACGGTCGCCCGAGCCTGTTGCAACGCCTGTTCGGCGGCAAGGAGTCGGAAACCACCGCGGAGCCGAGCGCATC
GGTGCCGTCCGTTGTGGCGGCAAGCAATACACCGATCCAACCGGCGGCGGCCGCGCCGTCCCTGCCGGTCGCCGAGCACG
ACGAGGCGCCAGGCGGTCCGCCGCAGCCGTTGCCCGCCCGCACGGTCGCCGCCATCGAAAGCGCGCCAGCGGGTTGGGTC
GGGGTCGCCGAGCGTGGCGAGCCGAACCAGATCCTGCTGGATGAGCCCCGGGAAATCTGGCTCGACAGCCTGCCGCTACC
GGCCGGCCTGAGCTTTAGCGAGACGCTGGAAGAAGCGGGTGCGGAGCCGTCGCCCGCAATGCCGGCGGACGTTGAAAGCG
CGCCCGAAGCTCCGGCCACTCCTGTGGATAACCTCGACGGGCAGGCGGTAGACGAGGCCTACGAACTGCCGCCGCCGATA
CCGGAGCCCGGCTACAGCGCGGTGGCGCCGCACATCGAGGCCAGCCTGCTGCGGCTGCTCGACGGCCTGTCCCTGCCGAG
CAGCCACCAGCCCCAGGCCGAGGCGCTGCGGGAGCGGATCGATGGCAGCCTGAACTGGTATGAGCTGGTGCCGGTACTCG
ACGACCTGGCGGTGCTGGTGCTGTCCCTGGCGGACAGTGGCCAGCGCGACTTCGAGGAATACCTGCGGCAACTCAACGAG
CGCCTGGAAAGCTTCCTCGGCCACCTGGGCGACGCCCACGCCGGCTATACCGACGTGCTGGACAACGCGCGCGGCTTCGA
CCAATCGCTGCGTGAGCAGGTCAGTGGCCTGCAGGCCAGCGTGCAGCAGGCGACCGACCTGAACAGCCTCAAGCTGGCGG
TGGACAGCCGGCTGAACGGCCTGCTTGCCTCCATGGACGAACACCAGCGCGAACAGGCCGAGCACGAACAGGAGGTGTCC
GGCCGCCTGCAGGCGCTGATGGAGCGGGTCAACAGCATGGAGCAGGATGCCAAGGCGTTCCACAGCCACCTGGAGGACCA
GCGACAGAAAGCCCTGACCGATCCGCTGACCGGCCTGCCCAACCGCGCGGCGCTCAGCGAGCGCCTGGAACAGGAAGTGG
CGCGCCGGCACCGGGACGGCGGCGATCTGCTGCTGGCGGTGCTGGACATCGACCACTTCAAGCGGATCAACGACGACTTC
GGCCACCTGGCCGGGGACAAGGTGCTGAAGATCATTGCCGGCGAATTGCGCAAACGGTTGCGCCAGGCCGATTTCATCGC
CCGTTTCGGCGGCGAGGAGTTCGTCGTCCTGCTCCCGGCCACGTCCCTGGAAGCCGGCCGGCAACTGCTCGAACGGCTGC
GCGCGGCGATCGCCGCCTGTCCGTTCCATTTCAAGGGCGAGCCCCTGAGCATCACCTGTTCCGCCGGCATCACCGCGTTC
GAAGGCAACGAGGCCGGCGAAGCGGTTTTCGAGCGTGCCGACCAGGCGCTGTATCGAGCCAAGCGCGCCGGCCGGGACCG
CCTGGAAGTGGCCTGA