Detailed information of regulator


Summary

Regulator ID REG0016 experimental
Regulator type protein
Regulatory pathway (from literatures) Tpp
KEGG pathway (determined by BlastKOALA) -
Related T6SS T6SS00929 experimental (Type i3)
Strain Serratia marcescens subsp. marcescens Db11
Replicon chromosome
Sequence Protein sequence (329 a.a.); Nucleotide sequence (987 bp)
Description RtkS is an upstream activator of PpkA which stabilises the kinase through a direct interaction.
Reference

External database links

Locus tag (Gene) SMDB11_2269 (RtkS)
Coordinates (Strand) 2391034..2392020 (+)
NCBI ID 560174112
GenBank HG326223
Uniprot ID UPI000321F8FA
KEGG ID -
KEGG pathway (determined by BlastKOALA) -
PDB ID -

  Target
Target Regulation (↓/↑) Target sequence
SMDB11_2275 (PpKA) 560174118

Pfam domain hit(s) of regulator

Domain Pfam ID E-value Aligned region

Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-328 MKYWMPGLVALMAVPTAQAMNYRLVYSPSQKLEVFIDDVKNSNPASWCGKSIPLRIVSAQSQDPAVLNDFLPRVGNLLEKQCPKAGHLPWTLTDKRGEKLASGEAAKARGWKPVVKQEAVEQPETPPQPAIPAAVAVTSPQADTAPPQRFSLPQGCHFRTFWGDEANGGALFIPAGEALRCGEDGWLQGSGAVTLQQGGQTLSPTLWFLQGYPLAKVNGGDRALTVVSANAQRLVLGGNPQAPGSFLLLSFEPKLHAWAFNGEAIVEMPRVDAADENKVKQHVQQAQTAWQPLLSAPAPLTFKLVEKLAADRVDPASGSYLSVNGATH



Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
SP(Sec/SPI) 0.9963 pos: 19-20. AQA-MN. MKYWMPGLVALMAVPTAQA



  Protein sequence of regulator: 329 a.a.    .

>REG0016 HG326223:2391034-2392020 [Serratia marcescens subsp. marcescens Db11]
MKYWMPGLVALMAVPTAQAMNYRLVYSPSQKLEVFIDDVKNSNPASWCGKSIPLRIVSAQSQDPAVLNDFLPRVGNLLEK
QCPKAGHLPWTLTDKRGEKLASGEAAKARGWKPVVKQEAVEQPETPPQPAIPAAVAVTSPQADTAPPQRFSLPQGCHFRT
FWGDEANGGALFIPAGEALRCGEDGWLQGSGAVTLQQGGQTLSPTLWFLQGYPLAKVNGGDRALTVVSANAQRLVLGGNP
QAPGSFLLLSFEPKLHAWAFNGEAIVEMPRVDAADENKVKQHVQQAQTAWQPLLSAPAPLTFKLVEKLAADRVDPASGSY
LSVNGATH*

  Nucleotide sequence of regulator: 987 bp    .

>REG0016 HG326223:2391034-2392020 [Serratia marcescens subsp. marcescens Db11]
ATGAAATATTGGATGCCGGGGCTCGTCGCCCTGATGGCGGTGCCGACCGCGCAGGCGATGAACTATCGCCTGGTTTACTC
CCCCAGCCAGAAGCTGGAAGTGTTTATCGATGACGTCAAAAACAGCAATCCGGCAAGCTGGTGCGGCAAGAGCATCCCGC
TGCGCATCGTCTCGGCGCAAAGCCAGGATCCGGCGGTGCTGAACGACTTCCTGCCGCGCGTCGGCAATCTGTTGGAAAAG
CAGTGCCCGAAAGCCGGCCACCTGCCCTGGACGCTGACCGACAAGCGCGGTGAGAAGCTGGCCAGCGGCGAAGCCGCCAA
AGCGCGCGGCTGGAAACCGGTGGTCAAACAGGAGGCCGTCGAGCAGCCGGAAACCCCGCCGCAGCCGGCTATCCCTGCTG
CAGTGGCCGTGACTTCTCCGCAGGCGGACACCGCGCCGCCTCAGCGTTTCAGCCTGCCGCAGGGCTGCCACTTCCGCACC
TTCTGGGGTGACGAAGCCAACGGCGGCGCGCTATTCATTCCCGCTGGTGAGGCGCTGCGCTGCGGCGAGGACGGCTGGCT
GCAGGGCAGCGGCGCGGTCACGCTGCAACAGGGCGGCCAAACCCTCTCGCCGACGCTGTGGTTCCTGCAAGGTTACCCGC
TGGCGAAGGTGAACGGCGGCGATCGCGCGCTGACCGTCGTCAGCGCCAACGCCCAACGGCTGGTTTTGGGCGGCAACCCG
CAGGCGCCGGGCAGCTTCCTGCTGCTGAGCTTCGAACCGAAGCTGCACGCCTGGGCGTTCAACGGTGAAGCGATCGTTGA
AATGCCGCGCGTCGATGCCGCCGACGAGAACAAGGTCAAACAGCACGTACAGCAGGCGCAAACCGCCTGGCAGCCGCTGC
TAAGCGCCCCCGCCCCGCTGACCTTCAAGCTGGTGGAAAAGCTGGCCGCAGACCGCGTCGATCCTGCCAGCGGCAGCTAC
CTGTCGGTTAACGGCGCCACTCACTGA