Detailed information of regulator


Summary

Regulator ID REG0015 experimental
Regulator type protein
Regulatory pathway (from literatures) Tpp
KEGG pathway (determined by BlastKOALA) -
Related T6SS T6SS00929 experimental (Type i3)
Strain Serratia marcescens subsp. marcescens Db11
Replicon chromosome
Sequence Protein sequence (258 a.a.); Nucleotide sequence (774 bp)
Description PppA-mediated dephosphorylation of Fha is required for partial disassembly and re-assembly of the T6SS at a new location in the cell.
Reference
External database links

Locus tag (Gene) SMDB11_2268 (PppA)
Coordinates (Strand) 2390232..2391005 (+)
NCBI ID 560174111
GenBank HG326223
Uniprot ID UPI000326728F
KEGG ID -
KEGG pathway (determined by BlastKOALA) -
PDB ID -
  Target
Target Regulation (↓/↑) Target sequence
SMDB11_2267 (FHA) ↑ 560174110
Pfam domain hit(s) of regulator

Domain Pfam ID E-value Aligned region
PP2C_2 PF13672.8 3.9e-14 8..198
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-257 MNITIASTSNQGGRASNQDQTGEVLGNRAACFVVCDGIAGFPGGDIAAKLARDTILQNFDGEKHLNAQSIRQHITSANAAIHQQQRQSDEYSKMGTTLVSLFIDRDYQLAYWAHAGDSRLYLFRRGYLHTVTTDHSLIQQMQDAGYQTNGINSNLLYFALGLNEERDATYSDVLQLEDGDVFLLCTDGFWHSFSQAELEQSLHMVNSPSEWIALMQQAWKKNNNSDNYSAIAVWIGSPQETTLLHSLADAERFLSRD


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9029 - -


  Protein sequence of regulator: 258 a.a.    .

>REG0015 HG326223:2390232-2391005 [Serratia marcescens subsp. marcescens Db11]
MNITIASTSNQGGRASNQDQTGEVLGNRAACFVVCDGIAGFPGGDIAAKLARDTILQNFDGEKHLNAQSIRQHITSANAA
IHQQQRQSDEYSKMGTTLVSLFIDRDYQLAYWAHAGDSRLYLFRRGYLHTVTTDHSLIQQMQDAGYQTNGINSNLLYFAL
GLNEERDATYSDVLQLEDGDVFLLCTDGFWHSFSQAELEQSLHMVNSPSEWIALMQQAWKKNNNSDNYSAIAVWIGSPQE
TTLLHSLADAERFLSRD*

  Nucleotide sequence of regulator: 774 bp    .

>REG0015 HG326223:2390232-2391005 [Serratia marcescens subsp. marcescens Db11]
ATGAATATCACCATAGCCTCTACCTCCAACCAGGGCGGCCGCGCCTCCAACCAGGATCAGACCGGCGAGGTGCTCGGCAA
CCGCGCCGCCTGCTTCGTGGTGTGCGACGGCATCGCCGGTTTTCCGGGCGGCGATATCGCCGCCAAACTGGCACGCGACA
CCATTTTGCAAAACTTCGACGGCGAAAAGCACCTGAACGCCCAGAGCATTCGTCAGCACATCACCAGCGCCAACGCCGCC
ATCCACCAGCAGCAGCGGCAGTCGGACGAATACAGCAAGATGGGCACCACGCTGGTCAGTCTGTTTATCGATCGCGATTA
CCAGCTGGCCTACTGGGCGCACGCCGGCGACAGCCGCCTGTACCTGTTCCGCCGCGGCTACCTGCATACCGTCACCACCG
ACCACAGCCTGATCCAACAGATGCAGGACGCCGGCTACCAGACCAACGGCATCAACAGCAACCTGCTGTATTTCGCGCTG
GGGCTCAACGAAGAGCGCGACGCCACCTACAGCGACGTGCTGCAGCTGGAAGACGGCGACGTTTTCCTGCTGTGCACCGA
CGGCTTCTGGCACAGCTTCAGCCAGGCCGAACTGGAACAGTCGCTGCATATGGTCAACTCCCCCAGCGAGTGGATCGCCC
TGATGCAGCAGGCATGGAAGAAAAACAATAACAGCGATAACTACAGCGCTATCGCCGTCTGGATTGGCTCACCGCAGGAA
ACCACCCTGCTGCATTCGCTGGCGGATGCGGAGCGGTTTCTGAGCCGCGACTGA