Detailed information of immunity protein
Summary
| Immunity protein ID | IMU17296  |
| Cognate effector | EFF18620 |
| Related T6SS (Type) | T6SS00050 (Type i1) |
| Strain | Photorhabdus laumondii subsp. laumondii TTO1 |
| Replicon | chromosome |
| Sequence | Protein sequence (140 a.a.); Nucleotide sequence (420 bp) |
| Description | The Plu0352 protein conferred protection against Tre23, suggesting that Plu0352 acts as an immunity protein against the Tre23 toxin. |
| Reference |
Experimental investigation has been performed.
Bioinformatics investigation has been performedExternal database links
| Locus tag (Gene) | Plu0352 (Tri23) |
| Coordinates (Strand) | 377114..377533 (-) |
| NCBI ID | WP_011144746.1 |
| RefSeq | NC_005126 |
| Uniprot ID | A0A6L9JS13_PHOLM, Q7N9H9_PHOLL |
| KEGG ID | plu:plu0354, plum:A4R40_01725 |
| PDB ID | - |
Pfam domain hit(s)
| Domain | Pfam ID | E-value | Aligned region |
|---|---|---|---|
| DcrB | PF08786.13 | 6.3e-40 | 10..135 |
Transmembrane helices
- Transmembrane helices are predicted using TMHMM 2.0 software.
| Prediction | Region | Sequence |
|---|---|---|
| Outside | 1-139 | MENTTYQMNEGSLAIPGNWRDESMNVFVLPDDSGINLVVSRTPVPAGMDNPAYYEQTLEQFCTHLPGYQEHQRSEITLSQQPARRLDYQWTSPEGDMYQTVILQIRGPLLLTFNLTSPAPFEAGQRDTLLAIVHSFQAA |
Signal peptides
- Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
- Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
- Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
| Prediction | Probability | Cleavage site | Signal peptide sequence |
|---|---|---|---|
| Other | 0.9844 | - | - |
Protein sequence: 140 a.a. .
>IMU17296 NC_005126:c377533-377114 [Photorhabdus laumondii subsp. laumondii TTO1]
MENTTYQMNEGSLAIPGNWRDESMNVFVLPDDSGINLVVSRTPVPAGMDNPAYYEQTLEQFCTHLPGYQEHQRSEITLSQ
QPARRLDYQWTSPEGDMYQTVILQIRGPLLLTFNLTSPAPFEAGQRDTLLAIVHSFQAA*
MENTTYQMNEGSLAIPGNWRDESMNVFVLPDDSGINLVVSRTPVPAGMDNPAYYEQTLEQFCTHLPGYQEHQRSEITLSQ
QPARRLDYQWTSPEGDMYQTVILQIRGPLLLTFNLTSPAPFEAGQRDTLLAIVHSFQAA*
Nucleotide sequence: 420 bp .
>IMU17296 NC_005126:c377533-377114 [Photorhabdus laumondii subsp. laumondii TTO1]
ATGGAAAACACAACCTATCAGATGAATGAAGGCTCACTGGCTATCCCGGGCAACTGGCGGGATGAATCCATGAATGTATT
TGTGCTGCCGGACGACAGCGGCATCAATCTGGTGGTCAGCCGCACCCCGGTCCCCGCCGGCATGGATAACCCCGCTTACT
ATGAACAGACCCTGGAGCAGTTCTGCACCCATCTGCCCGGGTACCAGGAGCATCAGCGCAGCGAAATCACCCTCAGCCAG
CAACCCGCCCGCCGTCTGGATTACCAGTGGACAAGCCCGGAAGGCGACATGTACCAGACCGTGATACTGCAAATCCGGGG
CCCGCTGCTGCTGACCTTCAACCTGACCTCCCCCGCGCCTTTTGAAGCCGGCCAGCGTGATACCCTGCTGGCAATTGTCC
ACAGTTTTCAGGCAGCCTGA
ATGGAAAACACAACCTATCAGATGAATGAAGGCTCACTGGCTATCCCGGGCAACTGGCGGGATGAATCCATGAATGTATT
TGTGCTGCCGGACGACAGCGGCATCAATCTGGTGGTCAGCCGCACCCCGGTCCCCGCCGGCATGGATAACCCCGCTTACT
ATGAACAGACCCTGGAGCAGTTCTGCACCCATCTGCCCGGGTACCAGGAGCATCAGCGCAGCGAAATCACCCTCAGCCAG
CAACCCGCCCGCCGTCTGGATTACCAGTGGACAAGCCCGGAAGGCGACATGTACCAGACCGTGATACTGCAAATCCGGGG
CCCGCTGCTGCTGACCTTCAACCTGACCTCCCCCGCGCCTTTTGAAGCCGGCCAGCGTGATACCCTGCTGGCAATTGTCC
ACAGTTTTCAGGCAGCCTGA