Detailed information of immunity protein


Summary

Immunity protein ID IMU00380 experimental
Cognate effector EFF01858 experimental
Related T6SS (Type) T6SS01242 experimental (Type i5)
Strain Agrobacterium tumefaciens strain 1D1108
Replicon chromosome
Sequence Protein sequence (331 a.a.); Nucleotide sequence (993 bp)
Description The direct expression of E11 in the parental 1D1108 strain caused a substantial reduction in growth and co-expression of I11_1, the gene immediately 3' to E11, led to a partial restoration in growth.
Reference
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
External database links

Locus tag (Gene) At1D1108_RS23285 (I11_1)
Coordinates (Strand) 2073146..2074138 (+)
NCBI ID 490566480
RefSeq NZ_CP032922
Uniprot ID UPI00023A48D8
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
DUF3396 PF11876.10 5.6e-23 164..325
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-330 MNLNELVGTMAILEERGELEKLSEIGLPPGNAIQWLFGLTAGFYFAGGETPRIRRAALDLAARYYDVTTGNTNLLTVSERSRRLSSRDDIERHLAQANYLDEKETVGFYIRHMPAQALRSTDPVHDYLTALLPGIGYRGGCGHLMYQTRLSELSLDPVGVVRSFVDACRDLQVFYAVSGMSLFFYSYAAGATEKAYPLFRRFPGLLYEDGIRFGLIISQRTDVIRDVNWLTAVNDELLARVGGLDKAREVLGDEIVLHPYEGGVVFQAGARPVLGDLNKGRVPAAYRAVNDFLKPLRYEAWDYPYLRAPYGVDEMEYTQWWTHRFDDGER


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9823 - -


  Protein sequence: 331 a.a.    .

>IMU00380 NZ_CP032922:2073146-2074138 [Agrobacterium tumefaciens]
MNLNELVGTMAILEERGELEKLSEIGLPPGNAIQWLFGLTAGFYFAGGETPRIRRAALDLAARYYDVTTGNTNLLTVSER
SRRLSSRDDIERHLAQANYLDEKETVGFYIRHMPAQALRSTDPVHDYLTALLPGIGYRGGCGHLMYQTRLSELSLDPVGV
VRSFVDACRDLQVFYAVSGMSLFFYSYAAGATEKAYPLFRRFPGLLYEDGIRFGLIISQRTDVIRDVNWLTAVNDELLAR
VGGLDKAREVLGDEIVLHPYEGGVVFQAGARPVLGDLNKGRVPAAYRAVNDFLKPLRYEAWDYPYLRAPYGVDEMEYTQW
WTHRFDDGER*

  Nucleotide sequence: 993 bp    .

>IMU00380 NZ_CP032922:2073146-2074138 [Agrobacterium tumefaciens]
ATGAATTTAAATGAACTAGTCGGCACGATGGCAATCCTCGAAGAGCGCGGTGAACTCGAGAAATTGAGCGAGATCGGTTT
GCCGCCGGGCAACGCGATTCAATGGCTGTTTGGCCTCACTGCTGGTTTCTATTTTGCAGGTGGTGAAACACCACGGATAC
GACGAGCCGCACTCGATCTGGCCGCGCGTTACTACGATGTGACGACAGGAAACACCAATCTGCTGACGGTCAGTGAACGT
TCGCGCCGTCTGTCTTCGAGAGATGACATTGAGCGACATCTAGCACAAGCCAATTACCTTGATGAGAAGGAGACCGTAGG
CTTCTATATCAGACACATGCCTGCCCAAGCTCTGCGGTCGACCGATCCGGTCCACGACTATTTGACGGCGCTTCTTCCCG
GTATTGGGTATCGTGGCGGCTGTGGGCACCTGATGTACCAGACGAGGTTGTCGGAACTATCGCTAGATCCAGTAGGTGTC
GTGCGTTCCTTCGTTGACGCCTGCCGTGATCTTCAGGTCTTTTATGCCGTTTCGGGGATGTCGCTTTTCTTTTATTCCTA
TGCGGCAGGAGCAACTGAAAAAGCCTATCCCTTGTTCCGTAGATTTCCCGGCCTTCTCTATGAGGATGGCATCCGTTTTG
GGTTAATCATTTCGCAGCGCACCGATGTAATCCGTGATGTGAATTGGCTTACAGCCGTCAACGATGAACTGCTGGCGCGG
GTCGGTGGTCTCGACAAGGCGAGAGAAGTGCTGGGAGACGAGATTGTCCTCCATCCCTACGAAGGAGGCGTCGTTTTCCA
GGCGGGTGCCCGGCCTGTACTCGGCGACTTGAACAAGGGGCGAGTCCCTGCTGCGTATCGCGCAGTCAACGATTTTCTCA
AGCCCCTGCGTTACGAGGCCTGGGATTATCCCTATCTGCGAGCGCCTTACGGTGTCGACGAGATGGAGTATACGCAATGG
TGGACGCATCGATTTGACGATGGTGAACGTTGA