Detailed information of immunity protein
Summary
| Immunity protein ID | IMU00377  |
| Cognate effector | EFF01808 |
| Related T6SS (Type) | T6SS00127 (Type i1) |
| Strain | Myxococcus xanthus DK 1622 |
| Replicon | chromosome |
| Sequence | Protein sequence (154 a.a.); Nucleotide sequence (462 bp) |
| Description | MXAN_RS24590 protein was able to bind to the MXAN_RS36995 protein, and the nuclease activity of MXAN_RS36995 was blocked by the presence of the His6-tagged MXAN_RS24590 protein. |
| Reference |
Experimental investigation has been performed.
Bioinformatics investigation has been performedExternal database links
| Locus tag (Gene) | MXAN_RS24590 |
| Coordinates (Strand) | 6337957..6338418 (-) |
| NCBI ID | 521967099 |
| RefSeq | NC_008095 |
| Uniprot ID | UPI000370DA7A |
| KEGG ID | - |
| PDB ID | - |
Pfam domain hit(s)
| Domain | Pfam ID | E-value | Aligned region |
|---|
Transmembrane helices
- Transmembrane helices are predicted using TMHMM 2.0 software.
| Prediction | Region | Sequence |
|---|---|---|
| Outside | 1-153 | MMPLHLFYDFDAPVRDDALVTERYANGGELHDRFETLGEMLAWGALLKFRVNTMPQRCEGMLSCDDPDLLSQLDPVMFSLGFTKPITTGPRCGLYERNDAVLICERTPREELLGNQAFTLGGRDAGVLRRLLGRLTTESSLEVEVDEWTPALG |
Signal peptides
- Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
- Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
- Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
| Prediction | Probability | Cleavage site | Signal peptide sequence |
|---|---|---|---|
| Other | 0.9927 | - | - |
Protein sequence: 154 a.a. .
>IMU00377 NC_008095:c6338418-6337957 [Myxococcus xanthus DK 1622]
MMPLHLFYDFDAPVRDDALVTERYANGGELHDRFETLGEMLAWGALLKFRVNTMPQRCEGMLSCDDPDLLSQLDPVMFSL
GFTKPITTGPRCGLYERNDAVLICERTPREELLGNQAFTLGGRDAGVLRRLLGRLTTESSLEVEVDEWTPALG*
MMPLHLFYDFDAPVRDDALVTERYANGGELHDRFETLGEMLAWGALLKFRVNTMPQRCEGMLSCDDPDLLSQLDPVMFSL
GFTKPITTGPRCGLYERNDAVLICERTPREELLGNQAFTLGGRDAGVLRRLLGRLTTESSLEVEVDEWTPALG*
Nucleotide sequence: 462 bp .
>IMU00377 NC_008095:c6338418-6337957 [Myxococcus xanthus DK 1622]
ATGATGCCACTGCATCTCTTCTACGATTTTGACGCACCGGTACGGGACGATGCGCTGGTGACGGAGCGGTACGCCAATGG
CGGCGAGCTTCATGACAGGTTCGAAACTCTGGGTGAAATGTTGGCTTGGGGGGCGCTCCTGAAGTTCAGGGTCAACACGA
TGCCTCAGCGATGTGAAGGAATGCTCTCTTGTGACGATCCAGACCTCCTCTCTCAACTCGATCCAGTGATGTTCAGTCTG
GGGTTCACCAAGCCGATTACAACCGGTCCTCGCTGTGGACTGTATGAACGGAACGATGCGGTCTTGATATGCGAGCGCAC
GCCCCGAGAAGAACTCCTGGGGAACCAGGCCTTCACTCTGGGCGGCCGTGATGCCGGAGTACTTAGAAGGCTCCTGGGAA
GGCTCACCACCGAGTCCTCGTTGGAGGTCGAAGTCGACGAATGGACCCCAGCGCTTGGATGA
ATGATGCCACTGCATCTCTTCTACGATTTTGACGCACCGGTACGGGACGATGCGCTGGTGACGGAGCGGTACGCCAATGG
CGGCGAGCTTCATGACAGGTTCGAAACTCTGGGTGAAATGTTGGCTTGGGGGGCGCTCCTGAAGTTCAGGGTCAACACGA
TGCCTCAGCGATGTGAAGGAATGCTCTCTTGTGACGATCCAGACCTCCTCTCTCAACTCGATCCAGTGATGTTCAGTCTG
GGGTTCACCAAGCCGATTACAACCGGTCCTCGCTGTGGACTGTATGAACGGAACGATGCGGTCTTGATATGCGAGCGCAC
GCCCCGAGAAGAACTCCTGGGGAACCAGGCCTTCACTCTGGGCGGCCGTGATGCCGGAGTACTTAGAAGGCTCCTGGGAA
GGCTCACCACCGAGTCCTCGTTGGAGGTCGAAGTCGACGAATGGACCCCAGCGCTTGGATGA