Detailed information of immunity protein


Summary

Immunity protein ID IMU00345 experimental
Cognate effector EFF01521 experimental
Related T6SS (Type) T6SS01200 experimental (Type i2)
Strain Escherichia coli KTE165
Replicon chromosome
Sequence Protein sequence (667 a.a.); Nucleotide sequence (2001 bp)
Description -
Reference
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
External database links

Locus tag (Gene) A31K_02347 (Hcp-ET2)
Coordinates (Strand) 2548806..2550806 (+)
NCBI ID 486402833
RefSeq NZ_KB733141
Uniprot ID UPI0002A1EBC4
KEGG ID -
PDB ID -
Pfam domain hit(s)

Domain Pfam ID E-value Aligned region
T6SS_HCP PF05638.14 6.6e-13 6..137
DUF2235 PF09994.11 6.7e-12 368..460
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-666 MGDIIYLRITGEQQGDISAGCGTQVSVGNRYQQGHEDEIFVFSFQGGVSNTGFGINHQAIQFCKILDKSSPLLMNCINNNERCRFEFYFYRINKYGKWERYYYIEVRGATLTQNQIIIKENELDYQYITIHYEYIYCKHLTANTEFSYLLTPENYNRLFPPTLLPVEEKPEIPPEREIILTIGVFFDGTGNNLTNTNLRMSFCQPETYGLDVQDLASFNKQCMSKQGKTGSGVQSYLNYYTNIHWLNKLYHKDSEINAKSAKIQREIYIEGIGTENNKADSLVGMGLGNNDTGVIAKTDRAISLLRETLAKIIVDLKDAKLVIKRLQFDVFGFSRGAAAARHFTNRVFERDPVLIKTIATAFQSVEYLGKPSGEVQFLGIFDTVAAIGGLMDGFDPHDGNNFPVKVKLPPGVAKHVFQLTAMNECRYNFCLNSIKESWPELSFPGSHADIGGGYDPLEDEYLFLSRPAIETVLGNVPVEATSAYQKAAQQAELLWRHSTLAPILPSGVLKIESNIDEIASPDHLGNVRKRVAAAVTFRRTITNDWSKIALRVMYEVAKEAGVVFDEIPDDDYYKYPEELSKICDKSISQAKDSLKKSTPQPFSSEELLVAGKYLHCSSNWNTVDYRLKNKVSAEVSAFKTFSFVNRPDENWTRTIYDMQGNKQNGI


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9683 - -


  Protein sequence: 667 a.a.    .

>IMU00345 NZ_KB733141:2548806-2550806 [Escherichia coli KTE165]
MGDIIYLRITGEQQGDISAGCGTQVSVGNRYQQGHEDEIFVFSFQGGVSNTGFGINHQAIQFCKILDKSSPLLMNCINNN
ERCRFEFYFYRINKYGKWERYYYIEVRGATLTQNQIIIKENELDYQYITIHYEYIYCKHLTANTEFSYLLTPENYNRLFP
PTLLPVEEKPEIPPEREIILTIGVFFDGTGNNLTNTNLRMSFCQPETYGLDVQDLASFNKQCMSKQGKTGSGVQSYLNYY
TNIHWLNKLYHKDSEINAKSAKIQREIYIEGIGTENNKADSLVGMGLGNNDTGVIAKTDRAISLLRETLAKIIVDLKDAK
LVIKRLQFDVFGFSRGAAAARHFTNRVFERDPVLIKTIATAFQSVEYLGKPSGEVQFLGIFDTVAAIGGLMDGFDPHDGN
NFPVKVKLPPGVAKHVFQLTAMNECRYNFCLNSIKESWPELSFPGSHADIGGGYDPLEDEYLFLSRPAIETVLGNVPVEA
TSAYQKAAQQAELLWRHSTLAPILPSGVLKIESNIDEIASPDHLGNVRKRVAAAVTFRRTITNDWSKIALRVMYEVAKEA
GVVFDEIPDDDYYKYPEELSKICDKSISQAKDSLKKSTPQPFSSEELLVAGKYLHCSSNWNTVDYRLKNKVSAEVSAFKT
FSFVNRPDENWTRTIYDMQGNKQNGI*

  Nucleotide sequence: 2001 bp    .

>IMU00345 NZ_KB733141:2548806-2550806 [Escherichia coli KTE165]
ATGGGTGACATTATATATTTACGCATTACAGGGGAGCAACAAGGGGATATTTCTGCAGGATGCGGGACGCAAGTCTCTGT
CGGGAATCGGTATCAACAGGGACATGAGGATGAAATATTTGTTTTTAGTTTTCAGGGAGGAGTAAGTAACACAGGATTTG
GCATTAATCATCAAGCGATACAATTTTGTAAAATTCTCGATAAAAGCTCACCGCTGCTGATGAATTGCATTAATAATAAC
GAACGATGCCGTTTTGAGTTTTATTTTTATCGTATTAATAAATATGGAAAATGGGAAAGGTATTATTATATTGAAGTCCG
TGGTGCCACGTTAACTCAGAATCAGATTATAATAAAAGAAAATGAACTCGACTATCAGTATATAACAATACACTACGAAT
ATATCTACTGTAAGCATCTTACAGCCAATACAGAATTTAGTTATTTACTCACACCTGAAAATTATAATCGCCTTTTCCCA
CCGACGCTCTTACCTGTCGAGGAAAAACCAGAAATACCGCCTGAACGAGAAATTATCCTCACCATTGGCGTATTCTTTGA
TGGCACAGGAAACAATTTAACCAATACGAATTTACGTATGAGTTTTTGCCAACCAGAAACCTATGGTCTGGATGTCCAGG
ATTTGGCCTCATTTAATAAACAATGTATGAGCAAGCAGGGTAAAACGGGATCCGGAGTACAGAGCTATTTGAATTACTAT
ACGAATATTCATTGGTTGAATAAGTTGTACCATAAAGACTCAGAAATAAATGCGAAGTCAGCTAAAATCCAACGTGAAAT
TTATATTGAAGGAATAGGCACTGAAAATAATAAAGCAGACTCTCTGGTAGGAATGGGGCTAGGAAATAATGATACTGGGG
TAATTGCCAAAACTGACCGTGCGATATCACTGCTTCGTGAGACACTGGCAAAGATTATTGTTGATTTAAAGGATGCTAAA
CTAGTAATTAAGCGTCTACAGTTTGACGTATTTGGCTTTAGTCGTGGGGCGGCAGCCGCACGGCACTTTACTAATCGCGT
ATTTGAACGTGATCCCGTACTGATTAAAACCATTGCGACGGCATTTCAGTCAGTTGAATATTTAGGTAAACCTTCCGGGG
AAGTGCAATTTTTAGGTATTTTTGACACAGTTGCAGCCATCGGAGGGCTGATGGATGGTTTTGACCCTCATGATGGTAAT
AACTTTCCGGTAAAAGTGAAGTTACCGCCAGGTGTGGCCAAACATGTATTCCAGCTCACAGCAATGAACGAATGTCGCTA
TAACTTTTGCCTCAACAGCATAAAGGAAAGCTGGCCAGAATTAAGTTTCCCTGGATCACATGCTGATATTGGTGGCGGCT
ATGACCCACTGGAAGATGAGTACCTGTTTTTAAGTCGCCCGGCGATTGAAACGGTACTGGGAAATGTGCCGGTGGAAGCG
ACAAGCGCTTACCAAAAAGCAGCACAGCAGGCAGAGTTATTGTGGCGCCATTCAACGCTGGCTCCGATTCTGCCTTCTGG
TGTCCTAAAAATTGAATCCAATATTGATGAAATAGCGTCGCCTGACCACTTAGGTAATGTGAGAAAACGGGTCGCTGCAG
CGGTGACATTTCGCAGAACGATCACCAATGACTGGTCAAAGATTGCGTTAAGAGTAATGTATGAAGTCGCTAAAGAGGCA
GGGGTAGTATTTGATGAAATACCAGATGATGATTATTATAAATATCCAGAGGAGTTAAGTAAAATATGTGATAAATCAAT
ATCACAAGCTAAAGATTCATTGAAAAAATCTACGCCACAACCTTTTTCTTCAGAAGAGTTACTCGTTGCCGGAAAATATT
TACACTGTTCTTCCAACTGGAATACCGTCGATTATCGATTAAAAAATAAGGTGTCTGCTGAAGTATCAGCGTTTAAGACG
TTTAGTTTTGTTAATCGGCCGGATGAAAATTGGACCAGAACTATATACGATATGCAAGGGAATAAACAAAATGGAATTTA
A