Detailed information of immunity protein


Summary

Immunity protein ID IMU00326 experimental
Cognate effector EFF01807 experimental
Related T6SS (Type) T6SS00272 experimental (Type i1)
Strain Proteus mirabilis HI4320
Replicon chromosome
Sequence Protein sequence (321 a.a.); Nucleotide sequence (963 bp)
Description PefE2 protects the toxicity of PefD from P. mirabilis strain BA6163
Reference
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed

External database links

Locus tag (Gene) PMI0762 (PefE2)
Coordinates (Strand) 845795..846757 (+)
NCBI ID 194682143
RefSeq NC_010554
Uniprot ID B4EVB5_PROMH
KEGG ID pmr:PMI0762
PDB ID -

Pfam domain hit(s)

Domain Pfam ID E-value Aligned region

Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-320 MEYITNKHWAKYIKGYIFTGCAIRDKNIVYFCLRKDIPYEKARNLWNSEIPSQLLCIYLDTPDDPIDYIRIEGFDNPKVGICLKPKEQGMLASRGDGGFVKCMGSGSKFPLEKVMDGDYANPKNIKCVGGYAYYVGTSREIYKRVDIGKWQRIQHGIPGGETNTDMGFTDLDGFSEQDMYAVGGAGDVWHYNGEIWIPCGFPSNEQLSAVLCAPDGYVYIGGEGGSLWRGREYQWEKLYHGSSAILLNQLRWFEDKVWACDDYRLQCWNGKEMVRPKDGDRNVIASGHMDVRDGILVVADDYNVDLYDGTAWHKIVRPYK



Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.8424 - -



  Protein sequence: 321 a.a.    .

>IMU00326 NC_010554:845795-846757 [Proteus mirabilis HI4320]
MEYITNKHWAKYIKGYIFTGCAIRDKNIVYFCLRKDIPYEKARNLWNSEIPSQLLCIYLDTPDDPIDYIRIEGFDNPKVG
ICLKPKEQGMLASRGDGGFVKCMGSGSKFPLEKVMDGDYANPKNIKCVGGYAYYVGTSREIYKRVDIGKWQRIQHGIPGG
ETNTDMGFTDLDGFSEQDMYAVGGAGDVWHYNGEIWIPCGFPSNEQLSAVLCAPDGYVYIGGEGGSLWRGREYQWEKLYH
GSSAILLNQLRWFEDKVWACDDYRLQCWNGKEMVRPKDGDRNVIASGHMDVRDGILVVADDYNVDLYDGTAWHKIVRPYK
*

  Nucleotide sequence: 963 bp    .

>IMU00326 NC_010554:845795-846757 [Proteus mirabilis HI4320]
ATGGAGTATATAACTAATAAACATTGGGCCAAATATATCAAGGGATATATTTTTACTGGTTGTGCAATCCGAGATAAAAA
TATTGTGTACTTTTGTTTGCGCAAAGATATTCCATACGAAAAGGCTCGAAATTTATGGAACAGCGAAATCCCCTCACAGT
TATTATGTATTTATTTAGACACACCAGATGACCCGATTGATTATATTAGAATTGAAGGGTTCGATAATCCTAAAGTAGGT
ATTTGTTTAAAACCGAAAGAACAAGGGATGCTTGCATCTAGAGGCGATGGTGGGTTTGTCAAGTGTATGGGCAGTGGATC
TAAATTTCCGCTAGAAAAAGTTATGGATGGTGACTATGCAAATCCTAAAAATATTAAATGTGTTGGTGGATATGCTTATT
ATGTTGGTACTTCGCGCGAAATTTATAAACGAGTGGATATTGGAAAATGGCAGAGAATTCAACATGGGATACCAGGAGGA
GAAACCAATACAGATATGGGATTCACTGATCTCGATGGTTTCTCTGAGCAGGATATGTATGCCGTTGGCGGTGCAGGTGA
TGTTTGGCATTATAATGGCGAAATCTGGATCCCTTGTGGTTTTCCCTCTAATGAGCAATTAAGTGCAGTATTGTGTGCCC
CTGATGGTTATGTGTATATCGGCGGTGAAGGGGGCAGTTTATGGCGAGGGCGTGAATACCAATGGGAAAAACTTTATCAC
GGCAGTTCGGCTATTTTACTGAATCAGTTACGCTGGTTTGAAGATAAAGTGTGGGCATGTGATGACTATCGCTTACAGTG
TTGGAATGGTAAAGAAATGGTCCGTCCCAAGGATGGTGATAGAAATGTTATCGCCTCAGGTCATATGGATGTCCGCGATG
GGATTTTAGTTGTAGCTGATGATTATAATGTTGATCTGTATGATGGAACCGCTTGGCATAAGATAGTGAGACCTTATAAA
TAA