Detailed information of immunity protein
Summary
| Immunity protein ID | IMU00303  |
| Cognate effector | EFF01370 |
| Related T6SS (Type) | T6SS00535 (Type i3) |
| Strain | Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344 |
| Replicon | chromosome |
| Sequence | Protein sequence (128 a.a.); Nucleotide sequence (384 bp) |
| Description | - |
| Reference |
Experimental investigation has been performed.
Bioinformatics investigation has been performedExternal database links
| Locus tag (Gene) | STM0278 (Tai4) |
| Coordinates (Strand) | 318129..318512 (+) |
| NCBI ID | 378698250 |
| RefSeq | NC_016810 |
| Uniprot ID | UPI00000CCE72 |
| KEGG ID | - |
| PDB ID | - |
Pfam domain hit(s)
| Domain | Pfam ID | E-value | Aligned region |
|---|---|---|---|
| Tai4 | PF16695.7 | 5.2e-23 | 39..121 |
Transmembrane helices
- Transmembrane helices are predicted using TMHMM 2.0 software.
| Prediction | Region | Sequence |
|---|---|---|
| Inside | 1-6 | VDTAVK |
| Transmembrane helix | 7-26 | WLILVTFSISGMLVWQPSFA |
| Outside | 27-127 | QEALTTQYSQSELLKNWALSHCLALVYKDDVVKNDARATASAYLEYGKQSVEIYHEIDEIAKKYSGLKYNGSISSDFNTMKCIDFIHDRELNELIKRRVEK |
Signal peptides
- Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
- Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
- Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
| Prediction | Probability | Cleavage site | Signal peptide sequence |
|---|---|---|---|
| SP(Sec/SPI) | 0.9545 | pos: 26-27. SFA-QE. | VDTAVKWLILVTFSISGMLVWQPSFA |
Protein sequence: 128 a.a. .
>IMU00303 NC_016810:318129-318512 [Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344]
VDTAVKWLILVTFSISGMLVWQPSFAQEALTTQYSQSELLKNWALSHCLALVYKDDVVKNDARATASAYLEYGKQSVEIY
HEIDEIAKKYSGLKYNGSISSDFNTMKCIDFIHDRELNELIKRRVEK*
VDTAVKWLILVTFSISGMLVWQPSFAQEALTTQYSQSELLKNWALSHCLALVYKDDVVKNDARATASAYLEYGKQSVEIY
HEIDEIAKKYSGLKYNGSISSDFNTMKCIDFIHDRELNELIKRRVEK*
Nucleotide sequence: 384 bp .
>IMU00303 NC_016810:318129-318512 [Salmonella enterica subsp. enterica serovar Typhimurium str. SL1344]
GTGGATACTGCCGTGAAATGGTTAATATTAGTTACTTTCAGCATAAGTGGAATGCTGGTATGGCAGCCATCCTTTGCACA
AGAAGCATTGACCACACAATATTCACAGTCGGAACTCTTAAAAAATTGGGCGCTGAGTCATTGTCTGGCATTAGTATACA
AAGATGATGTCGTTAAAAACGATGCCAGAGCTACGGCCAGTGCTTACCTTGAATATGGTAAACAATCTGTGGAGATTTAC
CATGAAATTGATGAGATTGCGAAAAAATATTCAGGGTTGAAATATAACGGTTCGATATCATCAGATTTTAATACCATGAA
GTGCATAGATTTTATCCATGACAGGGAATTAAATGAATTAATTAAAAGGCGTGTCGAGAAGTAA
GTGGATACTGCCGTGAAATGGTTAATATTAGTTACTTTCAGCATAAGTGGAATGCTGGTATGGCAGCCATCCTTTGCACA
AGAAGCATTGACCACACAATATTCACAGTCGGAACTCTTAAAAAATTGGGCGCTGAGTCATTGTCTGGCATTAGTATACA
AAGATGATGTCGTTAAAAACGATGCCAGAGCTACGGCCAGTGCTTACCTTGAATATGGTAAACAATCTGTGGAGATTTAC
CATGAAATTGATGAGATTGCGAAAAAATATTCAGGGTTGAAATATAACGGTTCGATATCATCAGATTTTAATACCATGAA
GTGCATAGATTTTATCCATGACAGGGAATTAAATGAATTAATTAAAAGGCGTGTCGAGAAGTAA