Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS01210  |
| T6SS type | Type Unknown |
| Strain | Escherichia coli strain O157 zh165 |
| Replicon (GenBank) | chromosome (KX118286) |
| Location | 1..6820 |
| Function | anti-bacterial |
| Comment | Neighborless Rhs-CT5 mediates interbacterial antagonism via Hcp2B and VgrG2 of T6SS2. |
| References | [1] Ma J, Sun M, Dong W, Pan Z, Lu C, Yao H et al (2017) PAAR-Rhs proteins harbor various C-terminal toxins to diversify the antibacterial pathways of type VI secretion systems. Environ Microbiol. (1):345-360. [PudMed:27871130] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | Ct5A | Ct5B | Ct5C | Ct5D |
| Number | 1 | 1 | 1 | 1 |
| Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| T6CP016167 | Ct5A | Locus_01 (ct5A) | 1..609 | - | 609 | 1062685042 | putative glutathione S-transferase |
| T6CP016168 | Ct5B | Locus_02 (ct5B) | 838..4971 | + | 4134 | 1062685043 | Rhs core protein |
| T6CP016169 | Ct5C | Locus_03 (ct5C) | 4992..5834 | + | 843 | 1062685044 | HEAT-like repeat immunity protein of toxin_55 RNase toxin |
| T6CP016170 | Ct5D | Locus_04 (ct5D) | 5882..6820 | + | 939 | 1062685045 | hypothetical protein |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.| Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.| Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
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Experimental investigation has been performed.| Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
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