Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   ABC804_RS01970 Genome accession   NZ_CP155536
Coordinates   362261..363517 (+) Length   418 a.a.
NCBI ID   WP_363860669.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain M264-3     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 357261..368517
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABC804_RS01940 (ABC804_01940) - 357890..358060 (-) 171 WP_000742180.1 PhrA family quorum-sensing system peptide -
  ABC804_RS01945 (ABC804_01945) - 358249..359112 (+) 864 WP_001093620.1 helix-turn-helix transcriptional regulator -
  ABC804_RS01950 (ABC804_01950) comM 359495..360115 (+) 621 WP_000839908.1 hypothetical protein Regulator
  ABC804_RS01955 (ABC804_01955) tsaE 360201..360644 (+) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  ABC804_RS01960 (ABC804_01960) - 360634..361152 (+) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  ABC804_RS01965 (ABC804_01965) - 361160..362176 (+) 1017 WP_000239282.1 LCP family protein -
  ABC804_RS01970 (ABC804_01970) cinA 362261..363517 (+) 1257 WP_363860669.1 competence/damage-inducible protein A Machinery gene
  ABC804_RS01975 (ABC804_01975) recA 363572..364738 (+) 1167 WP_001085463.1 recombinase RecA Machinery gene
  ABC804_RS01980 (ABC804_01980) - 365045..366415 (+) 1371 WP_001036293.1 MATE family efflux transporter -
  ABC804_RS01985 (ABC804_01985) lytA 366791..367747 (+) 957 WP_000405240.1 N-acetylmuramoyl-L-alanine amidase LytA -
  ABC804_RS01990 (ABC804_01990) - 368106..368267 (+) 162 WP_000289348.1 helix-turn-helix transcriptional regulator -
  ABC804_RS01995 (ABC804_01995) - 368254..368460 (+) 207 WP_000366087.1 hypothetical protein -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45123.57 Da        Isoelectric Point: 4.6498

>NTDB_id=997409 ABC804_RS01970 WP_363860669.1 362261..363517(+) (cinA) [Streptococcus pneumoniae strain M264-3]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQT
LAKFLGKALVFDPQAQEKLDIFFALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLRLSTKASSQEEANQALYILENQI
LDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQGKTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRML
DIPAKNLEEHGVVSEFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIGGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=997409 ABC804_RS01970 WP_363860669.1 362261..363517(+) (cinA) [Streptococcus pneumoniae strain M264-3]
ATGAAAGCAGAAATCATTGCTGTTGGAACAGAGATTTTGACAGGACAGATTGTCAACACCAATGCCCAGTTTTTGTCGGA
AAAACTAGCTGAGATTGGGGTAGATGTATATTTTCAGACGGCTGTAGGAGACAATGAAGTTCGTCTCTTGTCTTTGCTTG
AGATTGCCAGTCAACGTAGCAGTCTGGTGATTTTGACAGGCGGTTTGGGGCCAACTGAGGACGACCTAACCAAACAAACC
CTAGCTAAATTTTTAGGGAAAGCATTAGTCTTTGATCCTCAGGCTCAGGAGAAGTTGGATATCTTTTTTGCCCTGCGACC
AGACTATGCCCGAACACCGAATAACGAAAGACAAGCTCAAATTGTAGAAGGAGCGATTCCACTGCCAAACGAAACAGGAC
TGGCTGTTGGAGGAAAATTAGAAGTAGACGGAGTGACCTATGTCGTCCTTCCAGGTCCGCCAAGTGAATTGAAACCCATG
GTCTTAAACCAACTTCTACCCAAGTTGATGACAGGGAGCAAGCTGTATTCCCGAGTTCTTCGTTTCTTTGGGATTGGCGA
GAGCCAGCTGGTTACGATTTTGGCTGATTTAATTGATAATCAGATCGATCCTACCTTGGCCCCTTATGCCAAGACAGGAG
AAGTCACTCTACGTCTGTCAACAAAGGCTAGCAGTCAAGAAGAGGCGAATCAAGCGCTGTATATCTTGGAAAATCAAATC
TTGGACTGCCAGACTTTCGAAGGAATTTCTTTACGAGACTTTTGCTATGGTTATGGGGAAGAAACTAGTTTAGCCAGCAT
TGTGGTAGAAGAACTGAAAAGGCAAGGGAAAACCATCGCGGCTGCAGAGAGTTTGACGGCAGGTCTTTTCCAAGCTACCG
TGGCGAATTTTTCTGGAGTTTCAAGTATATTTAAGGGTGGTTTTGTGACCTATAGCTTGGAGGAAAAATCAAGGATGTTG
GATATTCCTGCCAAGAATTTGGAAGAACATGGTGTGGTGTCTGAATTTACAGCTCAGAAGATGGCTGAGCAGGCACGAAG
CAAGACCCAGTCTGATTTTGGAATTAGTTTGACCGGAGTGGCAGGACCAGATAGCCTAGAAGGACACCCAGTTGGGACAG
TCTTCATAGGCTTGGCGCAAGAGCAAGGAACTGAGGTTATCAAGGTTAATATTGGAGGCAGAAGCCGAGCAGATGTACGT
CATATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(262-414)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus pneumoniae TIGR4

99.282

100

0.993
  cinA Streptococcus pneumoniae Rx1

99.043

100

0.99
  cinA Streptococcus pneumoniae R6

99.043

100

0.99
  cinA Streptococcus pneumoniae D39

98.804

100

0.988
  cinA Streptococcus mitis SK321

93.78

100

0.938
  cinA Streptococcus mitis NCTC 12261

93.541

100

0.935
  cinA Streptococcus mutans UA159

70.813

100

0.708
  cinA Streptococcus suis isolate S10

55.048

99.522

0.548
  cinA Bacillus subtilis subsp. subtilis str. 168

45.455

100

0.455

Multiple sequence alignment